ID A0A1D8PTF1_CANAL Unreviewed; 465 AA.
AC A0A1D8PTF1;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 28-JUN-2023, entry version 27.
DE SubName: Full=Emp46p {ECO:0000313|EMBL:AOW31413.1};
GN Name=EMP46 {ECO:0000313|CGD:CAL0000179572,
GN ECO:0000313|EMBL:AOW31413.1};
GN OrderedLocusNames=CAALFM_CR07180WA {ECO:0000313|EMBL:AOW31413.1},
GN orf19.8350 {ECO:0000313|CGD:CAL0000179572};
OS Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=237561 {ECO:0000313|EMBL:AOW31413.1, ECO:0000313|Proteomes:UP000000559};
RN [1] {ECO:0000313|EMBL:AOW31413.1, ECO:0000313|Proteomes:UP000000559}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SC5314 / ATCC MYA-2876 {ECO:0000313|Proteomes:UP000000559};
RX PubMed=15123810; DOI=10.1073/pnas.0401648101;
RA Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B.,
RA Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W.,
RA Scherer S.;
RT "The diploid genome sequence of Candida albicans.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004).
RN [2] {ECO:0000313|EMBL:AOW31413.1, ECO:0000313|Proteomes:UP000000559}
RP GENOME REANNOTATION.
RC STRAIN=SC5314 / ATCC MYA-2876 {ECO:0000313|Proteomes:UP000000559};
RX PubMed=17419877; DOI=.1186/gb-2007-8-4-r52;
RA van het Hoog M., Rast T.J., Martchenko M., Grindle S., Dignard D.,
RA Hogues H., Cuomo C., Berriman M., Scherer S., Magee B.B., Whiteway M.,
RA Chibana H., Nantel A., Magee P.T.;
RT "Assembly of the Candida albicans genome into sixteen supercontigs aligned
RT on the eight chromosomes.";
RL Genome Biol. 8:RESEARCH52.1-RESEARCH52.12(2007).
RN [3] {ECO:0000313|EMBL:AOW31413.1, ECO:0000313|Proteomes:UP000000559}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SC5314 / ATCC MYA-2876 {ECO:0000313|Proteomes:UP000000559};
RX PubMed=24025428; DOI=.1186/gb-2013-14-9-r97;
RA Muzzey D., Schwartz K., Weissman J.S., Sherlock G.;
RT "Assembly of a phased diploid Candida albicans genome facilitates allele-
RT specific measurements and provides a simple model for repeat and indel
RT structure.";
RL Genome Biol. 14:RESEARCH97.1-RESEARCH97.14(2013).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP017630; AOW31413.1; -; Genomic_DNA.
DR RefSeq; XP_713090.2; XM_707997.2.
DR AlphaFoldDB; A0A1D8PTF1; -.
DR SMR; A0A1D8PTF1; -.
DR STRING; 237561.A0A1D8PTF1; -.
DR EnsemblFungi; CR_07180W_A-T; CR_07180W_A-T-p1; CR_07180W_A.
DR GeneID; 3645270; -.
DR KEGG; cal:CAALFM_CR07180WA; -.
DR CGD; CAL0000179572; EMP46.
DR VEuPathDB; FungiDB:CR_07180W_A; -.
DR eggNOG; ENOG502RYE9; Eukaryota.
DR InParanoid; A0A1D8PTF1; -.
DR OMA; VMAYYTF; -.
DR OrthoDB; 1332687at2759; -.
DR Proteomes; UP000000559; Chromosome R.
DR GO; GO:0030134; C:COPII-coated ER to Golgi transport vesicle; IBA:GO_Central.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IBA:GO_Central.
DR GO; GO:0005793; C:endoplasmic reticulum-Golgi intermediate compartment; IBA:GO_Central.
DR GO; GO:0000139; C:Golgi membrane; IBA:GO_Central.
DR GO; GO:0005537; F:mannose binding; IBA:GO_Central.
DR GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IBA:GO_Central.
DR Gene3D; 2.60.120.200; -; 1.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR005052; Lectin_leg.
DR PANTHER; PTHR12223:SF40; PROTEIN EMP46-RELATED; 1.
DR PANTHER; PTHR12223; VESICULAR MANNOSE-BINDING LECTIN; 1.
DR Pfam; PF03388; Lectin_leg-like; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR PROSITE; PS51328; L_LECTIN_LIKE; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000559};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 433..453
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 24..231
FT /note="L-type lectin-like"
FT /evidence="ECO:0000259|PROSITE:PS51328"
SQ SEQUENCE 465 AA; 53235 MW; 830B26CEBF7632C4 CRC64;
MLYHILLLIH VALAVVPNIP KISSQLSPNP HYSLPNLLSI ESKEDINNFD ISNNIQFDNG
RLLLGELGSI WGKYKIPTLN KPWTIELIFR STGTKEDRKY EDNSLNVWLL NEDNNNLPFD
SFDGFEISIN NEGQIPGVKL YNNDGSQNII HDASHVLGTC KFQYLDSDVP FTLRISYDAN
SWFKIQLDNN LCFKTNQISI PFQELKLGIT SKINQQSNEK FEILSLKTWE LLTADAIDDH
GLMIGDEIKI DVETEVKNDN QVKPNHIRES LMERAQRLRK EAIDSERQNL KNQDSNTNSQ
LDLILSKLNY LEVSLTGLNG GEDDSQILSI NKEITGLNNV FAELKSTVTD TKQAVVDLQN
VLVKQYSQML DSIAQLNQKV IGEVREQHYG MEELSRKVDL LMNNHKEIAY QYEKTRQDTQ
GEASKSGNVI DKLLKWILFP LVLILLVLVI FVYRLRHDIK HSKLL
//
