ID A0A1D8PTP5_CANAL Unreviewed; 417 AA.
AC A0A1D8PTP5;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 24-JAN-2024, entry version 37.
DE RecName: Full=Arf-GAP domain-containing protein {ECO:0008006|Google:ProtNLM};
GN OrderedLocusNames=CAALFM_CR08290WA {ECO:0000313|EMBL:AOW31510.1},
GN orf19.13751 {ECO:0000313|CGD:CAL0000185294};
OS Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=237561 {ECO:0000313|EMBL:AOW31510.1, ECO:0000313|Proteomes:UP000000559};
RN [1] {ECO:0000313|EMBL:AOW31510.1, ECO:0000313|Proteomes:UP000000559}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SC5314 / ATCC MYA-2876 {ECO:0000313|Proteomes:UP000000559};
RX PubMed=15123810; DOI=10.1073/pnas.0401648101;
RA Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B.,
RA Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W.,
RA Scherer S.;
RT "The diploid genome sequence of Candida albicans.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004).
RN [2] {ECO:0000313|EMBL:AOW31510.1, ECO:0000313|Proteomes:UP000000559}
RP GENOME REANNOTATION.
RC STRAIN=SC5314 / ATCC MYA-2876 {ECO:0000313|Proteomes:UP000000559};
RX PubMed=17419877; DOI=.1186/gb-2007-8-4-r52;
RA van het Hoog M., Rast T.J., Martchenko M., Grindle S., Dignard D.,
RA Hogues H., Cuomo C., Berriman M., Scherer S., Magee B.B., Whiteway M.,
RA Chibana H., Nantel A., Magee P.T.;
RT "Assembly of the Candida albicans genome into sixteen supercontigs aligned
RT on the eight chromosomes.";
RL Genome Biol. 8:RESEARCH52.1-RESEARCH52.12(2007).
RN [3] {ECO:0000313|EMBL:AOW31510.1, ECO:0000313|Proteomes:UP000000559}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SC5314 / ATCC MYA-2876 {ECO:0000313|Proteomes:UP000000559};
RX PubMed=24025428; DOI=.1186/gb-2013-14-9-r97;
RA Muzzey D., Schwartz K., Weissman J.S., Sherlock G.;
RT "Assembly of a phased diploid Candida albicans genome facilitates allele-
RT specific measurements and provides a simple model for repeat and indel
RT structure.";
RL Genome Biol. 14:RESEARCH97.1-RESEARCH97.14(2013).
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DR EMBL; CP017630; AOW31510.1; -; Genomic_DNA.
DR RefSeq; XP_716233.2; XM_711140.2.
DR AlphaFoldDB; A0A1D8PTP5; -.
DR SMR; A0A1D8PTP5; -.
DR EnsemblFungi; CR_08290W_A-T; CR_08290W_A-T-p1; CR_08290W_A.
DR GeneID; 3642103; -.
DR KEGG; cal:CAALFM_CR08290WA; -.
DR CGD; CAL0000185294; orf19.13751.
DR VEuPathDB; FungiDB:CR_08290W_A; -.
DR eggNOG; KOG0703; Eukaryota.
DR InParanoid; A0A1D8PTP5; -.
DR OMA; FQNLQVS; -.
DR OrthoDB; 1022106at2759; -.
DR Proteomes; UP000000559; Chromosome R.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005096; F:GTPase activator activity; IBA:GO_Central.
DR CDD; cd08204; ArfGap; 1.
DR Gene3D; 1.10.220.150; Arf GTPase activating protein; 1.
DR InterPro; IPR037278; ARFGAP/RecO.
DR InterPro; IPR001164; ArfGAP_dom.
DR InterPro; IPR038508; ArfGAP_dom_sf.
DR InterPro; IPR015940; UBA.
DR InterPro; IPR009060; UBA-like_sf.
DR PANTHER; PTHR45705; FI20236P1; 1.
DR PANTHER; PTHR45705:SF9; PROTEIN GTS1; 1.
DR Pfam; PF01412; ArfGap; 1.
DR PRINTS; PR00405; REVINTRACTNG.
DR SMART; SM00105; ArfGap; 1.
DR SUPFAM; SSF57863; ArfGap/RecO-like zinc finger; 1.
DR SUPFAM; SSF46934; UBA-like; 1.
DR PROSITE; PS50115; ARFGAP; 1.
DR PROSITE; PS50030; UBA; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00288};
KW Reference proteome {ECO:0000313|Proteomes:UP000000559};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00288};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00288}.
FT DOMAIN 12..139
FT /note="Arf-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50115"
FT DOMAIN 185..228
FT /note="UBA"
FT /evidence="ECO:0000259|PROSITE:PS50030"
FT REGION 137..174
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 236..268
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 373..417
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 146..174
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 246..268
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 417 AA; 47703 MW; E1A8EE355AFF8893 CRC64;
MFSKKQQKEK ERQLIEAVNS RGNDNKCGEC GASHPTWASY TLGILLCGRC ASVHKRVLGP
PNHNISKVKS LTLDNWTEEQ INQLRRIGNK KAKRKWNSKR IPFPYDGDDD VSAVEQYLRD
KYIAGKFRDD GIDNSEYDDR SSKFSDADQG SSYSQRASTR SRSNSARSQS ASIPRLTHRK
LTTFEYTQYY TQAMKIRSYG YNDRDAVLES LLLSNGNIEL ALDILEQDSK INPTKEEIAP
ELPRRPQPSS ANTNEKTQVS SDEWWNGNTT ASPQVPAITG AQTTGMPQIY QYTDPVTGQI
SYIDSNGQEY LDPNNPQHQN QLMQMSNPQL IAQQTNKQNI LSLYNQPTGQ AFTQQQQPQQ
QQQQQPQYTN TVYLQQQQQQ QPQQPQQQPQ FTGFGQTQQT GYMFGQYPQQ QNGYWRQ
//
