ID   A0A1D8RRY5_9GAMM        Unreviewed;       834 AA.
AC   A0A1D8RRY5;
DT   15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT   15-FEB-2017, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Peptidase S8 {ECO:0000313|EMBL:AOW75864.1};
GN   ORFNames=A3Q34_02745 {ECO:0000313|EMBL:AOW75864.1};
OS   Colwellia sp. PAMC 20917.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC   Colwelliaceae; Colwellia.
OX   NCBI_TaxID=1816218 {ECO:0000313|EMBL:AOW75864.1, ECO:0000313|Proteomes:UP000177820};
RN   [1] {ECO:0000313|EMBL:AOW75864.1, ECO:0000313|Proteomes:UP000177820}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PAMC 20917 {ECO:0000313|EMBL:AOW75864.1,
RC   ECO:0000313|Proteomes:UP000177820};
RA   Kim H.-W.;
RT   "Complete genome sequence of Colwellia sp. PAMC 20917.";
RL   Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase S8 family.
CC       {ECO:0000256|ARBA:ARBA00011073, ECO:0000256|PROSITE-ProRule:PRU01240}.
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DR   EMBL; CP014944; AOW75864.1; -; Genomic_DNA.
DR   RefSeq; WP_070373949.1; NZ_CP014944.1.
DR   AlphaFoldDB; A0A1D8RRY5; -.
DR   STRING; 1816218.A3Q34_02745; -.
DR   KEGG; coz:A3Q34_02745; -.
DR   OrthoDB; 9790784at2; -.
DR   Proteomes; UP000177820; Chromosome.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR   InterPro; IPR000209; Peptidase_S8/S53_dom.
DR   InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR   InterPro; IPR022398; Peptidase_S8_His-AS.
DR   InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR   InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR   InterPro; IPR001119; SLH_dom.
DR   PANTHER; PTHR43806:SF59; CEREVISIN-RELATED; 1.
DR   PANTHER; PTHR43806; PEPTIDASE S8; 1.
DR   Pfam; PF00082; Peptidase_S8; 1.
DR   Pfam; PF00395; SLH; 1.
DR   PRINTS; PR00723; SUBTILISIN.
DR   SUPFAM; SSF52743; Subtilisin-like; 1.
DR   PROSITE; PS51892; SUBTILASE; 1.
DR   PROSITE; PS00137; SUBTILASE_HIS; 1.
DR   PROSITE; PS00138; SUBTILASE_SER; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW   ProRule:PRU01240};
KW   Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW   ProRule:PRU01240}; Reference proteome {ECO:0000313|Proteomes:UP000177820};
KW   Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW   ProRule:PRU01240}; Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           25..834
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5009437168"
FT   DOMAIN          140..450
FT                   /note="Peptidase S8/S53"
FT                   /evidence="ECO:0000259|Pfam:PF00082"
FT   DOMAIN          618..658
FT                   /note="SLH"
FT                   /evidence="ECO:0000259|Pfam:PF00395"
FT   ACT_SITE        149
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT                   ECO:0000256|PROSITE-ProRule:PRU01240"
FT   ACT_SITE        201
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT                   ECO:0000256|PROSITE-ProRule:PRU01240"
FT   ACT_SITE        403
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT                   ECO:0000256|PROSITE-ProRule:PRU01240"
SQ   SEQUENCE   834 AA;  89109 MW;  4635FBF5B5D1B0A5 CRC64;
     MKKFTLSAIA AATMALTMPS QVFANAAIGE QLAEFLPTMV GSQTVMAVVT YNQLEPVSTT
     QLEHLSGLGI SQAVQFASVP VIGVVANLDQ IKAIAQRSDV RSVWLNRELE YFNSDARQIT
     GVDAVQGDEF FKQNGIEYTG KGVTVMVNDS GIDATHQDLF FGDKVIDNVQ GLTHASLLSI
     TGVTEGLILK NQPNTDTNSG HGTHCAGTIA GYGTMSDGKY PGAAPDAKLV GYGSGGVILI
     LDTIGAYDYA ITKGDSYENP LRVMSNSWGS SGKFDPTGPV SLASYKAHKM GILSVFAAGN
     SGSGEDTHNP YAQIPWGMSI GAGEKDGTLA GFSSRGYKYE SGEFTMPGGE KWTYNNEITI
     VAPGVDVIST RAVTNAGANG GEADVDAMDP THLPFYTMIS GTSMATPHVA GIVALMLEAN
     PDLDNMAIKK LLQESATNMP GYERFEVGAG FVNARAAVAA AKNYDMNHSV TVNNLRGKVF
     NANTLVEISE KSPEGSIWST PNGVTEPLGL QNSFDFQVHS EALWVKGSAS SLANTAKLVL
     IDPDGTEYFG NLTLPVLETG MRVTAPAMAG TWTVRVDGLT SLSGVNPDPL DLTNGPMAPE
     NFDVKINFED LIGFEGVSDI AAHRYENAIK YAVSKRLMDG LKNDNFNPDA KLKRKDLAKY
     LVMGGAVRQY RTLDSEPEPT LNEVPSGYKA IIESVSVVGG ALKDSLRTQQ PVMLSENGEF
     AHNGRVSKVD LAYSLVQILG LESMAKAFDP EKDNITVDYK GQTIVLADQD SIADNMKGYV
     QLAIQLSLLN VHFDVTQGTY DLTPQLNASF GGNYKVTRAE YALTAGRLFG QYFQ
//