ID A0A1D8RW36_9GAMM Unreviewed; 696 AA.
AC A0A1D8RW36;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=ATP-dependent DNA helicase RecG {ECO:0000256|ARBA:ARBA00017846, ECO:0000256|RuleBase:RU363016};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551, ECO:0000256|RuleBase:RU363016};
GN Name=recG {ECO:0000256|RuleBase:RU363016};
GN ORFNames=A3Q34_10955 {ECO:0000313|EMBL:AOW77331.1};
OS Colwellia sp. PAMC 20917.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Colwelliaceae; Colwellia.
OX NCBI_TaxID=1816218 {ECO:0000313|EMBL:AOW77331.1, ECO:0000313|Proteomes:UP000177820};
RN [1] {ECO:0000313|EMBL:AOW77331.1, ECO:0000313|Proteomes:UP000177820}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PAMC 20917 {ECO:0000313|EMBL:AOW77331.1,
RC ECO:0000313|Proteomes:UP000177820};
RA Kim H.-W.;
RT "Complete genome sequence of Colwellia sp. PAMC 20917.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Critical role in recombination and DNA repair. Helps process
CC Holliday junction intermediates to mature products by catalyzing branch
CC migration. Has a DNA unwinding activity characteristic of a DNA
CC helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-
CC DNA). {ECO:0000256|RuleBase:RU363016}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|RuleBase:RU363016};
CC -!- SIMILARITY: Belongs to the helicase family. RecG subfamily.
CC {ECO:0000256|ARBA:ARBA00007504, ECO:0000256|RuleBase:RU363016}.
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DR EMBL; CP014944; AOW77331.1; -; Genomic_DNA.
DR RefSeq; WP_070375398.1; NZ_CP014944.1.
DR AlphaFoldDB; A0A1D8RW36; -.
DR STRING; 1816218.A3Q34_10955; -.
DR KEGG; coz:A3Q34_10955; -.
DR Proteomes; UP000177820; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-UniRule.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-UniRule.
DR CDD; cd17992; DEXHc_RecG; 1.
DR CDD; cd04488; RecG_wedge_OBF; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR004609; ATP-dep_DNA_helicase_RecG.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR047112; RecG/Mfd.
DR InterPro; IPR045562; RecG_dom3_C.
DR InterPro; IPR033454; RecG_wedge.
DR NCBIfam; TIGR00643; recG; 1.
DR PANTHER; PTHR47964; ATP-DEPENDENT DNA HELICASE HOMOLOG RECG, CHLOROPLASTIC; 1.
DR PANTHER; PTHR47964:SF1; ATP-DEPENDENT DNA HELICASE HOMOLOG RECG, CHLOROPLASTIC; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF19833; RecG_dom3_C; 1.
DR Pfam; PF17191; RecG_wedge; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU363016};
KW DNA damage {ECO:0000256|RuleBase:RU363016};
KW DNA recombination {ECO:0000256|RuleBase:RU363016};
KW DNA repair {ECO:0000256|RuleBase:RU363016};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|RuleBase:RU363016};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU363016};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU363016};
KW Reference proteome {ECO:0000313|Proteomes:UP000177820}.
FT DOMAIN 286..451
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 485..631
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 696 AA; 77846 MW; 0A52F1025E84D399 CRC64;
MSKGLAKLAQ IAITSLKGVG PSMAEKLEKV GLRSLQDLLF HLPNRYEDRT RVTAIRDCFP
GVFTNIIGEI TGSQIINGKG RMLLVTVQDA SGTVTLRFFR FSAAQKNSLA LGLNIRCYGE
IKRGARGFEI IHPEYKSLDE DQHLTEVEET LTPVYPTTEG LRQITLRNLT EQALIRLERG
QVEELLPDEF NLQNYSLAQA LALIHRPPPE TSVIQLEEGK HPAQLRLIKE ELLAHNLSML
KLRQSSDAHR SISLIDDQVL SDKFLASLPF SPTNAQVRVV KEIRQDLMKT QPMMRLVQGD
VGSGKTLVAA LAALTAISKG FQVALMAPTE ILAEQHALNF KNWFEPLDIS VGWLAGKTKA
KARRSALEHI ENGSMQMIVG THALFQDKVI FHNLTLIIID EQHRFGVHQR LSLREKGAFE
GNYPHQLIMT ATPIPRTLAM TAYADLDTSI IDELPPGRTP INTIALPDTR REDVVERIRK
GCVEDNRQAY WVCTLIEESE VLQCQAAEDT AVYLQEQLTE LKIGLIHGRM KAVEKQSVME
TFKKGELDLL VATTVIEVGV DVPNSSLMVI ENPERLGLAQ LHQLRGRVGR GTVASHCVLM
YKSPLSKTAT KRLAVLRESN DGFVIAQKDL EIRGPGEFLG TKQTGLADLK IADLLRDAHL
IPEVQQHAYL IWKKHPQNAQ AIIQRWMGDR EYFTNA
//
