ID A0A1D8S4Z3_9EURY Unreviewed; 449 AA.
AC A0A1D8S4Z3; A0A1J1ACZ3;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=PBS lyase HEAT-like repeat domain-containing protein {ECO:0000313|EMBL:AOW80419.1};
GN ORFNames=HSR6_1313 {ECO:0000313|EMBL:APE95757.1}, HTSR_1241
GN {ECO:0000313|EMBL:AOW80419.1};
OS Halodesulfurarchaeum formicicum.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC Halobacteriaceae; Halodesulfurarchaeum.
OX NCBI_TaxID=1873524 {ECO:0000313|EMBL:AOW80419.1, ECO:0000313|Proteomes:UP000185608};
RN [1] {ECO:0000313|EMBL:AOW80419.1, ECO:0000313|Proteomes:UP000185608}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HTSR1 {ECO:0000313|EMBL:AOW80419.1,
RC ECO:0000313|Proteomes:UP000185608};
RA Sorokin D.Y., Kublanov I.V., Roman P., Sinninghe Damste J.S.,
RA Golyshin P.N., Rojo D., Ciordia S., Mena Md.C., Ferrer M., Smedile F.,
RA Messina E., La Cono V., Yakimov M.M.;
RT "Discovery of anaerobic lithoheterotrophic haloarchaeon capable of sulfur
RT respiration by hydrogen and formate.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000186165}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HSR6 {ECO:0000313|Proteomes:UP000186165};
RA Sorokin D.Y., Kublanov I.V., Roman P., Sinninghe Damste J.S.,
RA Golyshin P.N., Rojo D., Ciordia S., Mena Md.C., Ferrer M., Smedile F.,
RA Messina E., La Cono V., Yakimov M.M.;
RT "Discovery of first anaerobic lithoheterotrophic haloarchae widely
RT represented in hypersaline habitats.";
RL Submitted (AUG-2016) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:APE95757.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HSR6 {ECO:0000313|EMBL:APE95757.1};
RX PubMed=28106880; DOI=10.1038/ismej.2016.203;
RA Sorokin D.Y., Messina E., Smedile F., Roman P., Damste J.S.S., Ciordia S.,
RA Mena M.C., Ferrer M., Golyshin P.N., Kublanov I.V., Samarov N.I.,
RA Toshchakov S.V., La Cono V., Yakimov M.M.;
RT "Discovery of anaerobic lithoheterotrophic haloarchaea, ubiquitous in
RT hypersaline habitats.";
RL ISME J. 11:1245-1260(2017).
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DR EMBL; CP016070; AOW80419.1; -; Genomic_DNA.
DR EMBL; CP016804; APE95757.1; -; Genomic_DNA.
DR RefSeq; WP_070365108.1; NZ_CP016804.1.
DR AlphaFoldDB; A0A1D8S4Z3; -.
DR STRING; 1873524.HSR6_1313; -.
DR GeneID; 30417842; -.
DR KEGG; halh:HTSR_1241; -.
DR KEGG; hhsr:HSR6_1313; -.
DR PATRIC; fig|1855411.3.peg.1241; -.
DR OrthoDB; 293146at2157; -.
DR Proteomes; UP000185608; Chromosome.
DR Proteomes; UP000186165; Chromosome.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR004155; PBS_lyase_HEAT.
DR PANTHER; PTHR12697:SF5; DEOXYHYPUSINE HYDROXYLASE; 1.
DR PANTHER; PTHR12697; PBS LYASE HEAT-LIKE PROTEIN; 1.
DR Pfam; PF13646; HEAT_2; 1.
DR Pfam; PF03130; HEAT_PBS; 1.
DR SMART; SM00567; EZ_HEAT; 4.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 4: Predicted;
KW Lyase {ECO:0000313|EMBL:AOW80419.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000186165}.
FT REGION 1..83
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 419..449
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..15
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 35..51
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 58..83
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 423..449
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 449 AA; 47764 MW; E3A414AB674FA3CC CRC64;
MSDGDEEPAE TEADSIVTEF EERLESASQA VEAAETEADL DEVEATLEAI GADLEDADIP
VPEPEDEDEE PTDPTEELED ELSDLEDAVA DKRGPYGEDV IEAIEDVQST ITDTRWAEEG
ENELVPGVQD FLDTTAEILD ADFGKAVPDP EELSVTLGTV ADAVAEAEYD ADEDAETIAS
LLDATDTLAS AVDSATAWTD LEIRERLDRE GFYEPLEGAK HKDFPPEWSA LKTWQQRGNV
EMVVLLLDLM GDTDYITRHC IEALEYMGDE AGVDALTDLA NRRNLNAIDA IGKIGAESGV
SAVEGHAESG RTPELQARAI TALGAIGDES TTGTVADQLV ADSERVRTAA TRALGMIGDT
RAIDPLADVL GDVDEENSVR ASAAWALCQI GTEDALSAAA EYADASSYLI EAEAAKAADA
LGLEDEDDSE DPDDAEQAAA EEDSDEAAA
//
