ID A0A1D8S5R8_9EURY Unreviewed; 623 AA.
AC A0A1D8S5R8; A0A1J1ADR1;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=Bacterio-opsin activator HTH domain-containing protein {ECO:0000313|EMBL:AOW80699.1};
GN ORFNames=HSR6_1596 {ECO:0000313|EMBL:APE96037.1}, HTSR_1525
GN {ECO:0000313|EMBL:AOW80699.1};
OS Halodesulfurarchaeum formicicum.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC Halobacteriaceae; Halodesulfurarchaeum.
OX NCBI_TaxID=1873524 {ECO:0000313|EMBL:AOW80699.1, ECO:0000313|Proteomes:UP000185608};
RN [1] {ECO:0000313|EMBL:AOW80699.1, ECO:0000313|Proteomes:UP000185608}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HTSR1 {ECO:0000313|EMBL:AOW80699.1,
RC ECO:0000313|Proteomes:UP000185608};
RA Sorokin D.Y., Kublanov I.V., Roman P., Sinninghe Damste J.S.,
RA Golyshin P.N., Rojo D., Ciordia S., Mena Md.C., Ferrer M., Smedile F.,
RA Messina E., La Cono V., Yakimov M.M.;
RT "Discovery of anaerobic lithoheterotrophic haloarchaeon capable of sulfur
RT respiration by hydrogen and formate.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000186165}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HSR6 {ECO:0000313|Proteomes:UP000186165};
RA Sorokin D.Y., Kublanov I.V., Roman P., Sinninghe Damste J.S.,
RA Golyshin P.N., Rojo D., Ciordia S., Mena Md.C., Ferrer M., Smedile F.,
RA Messina E., La Cono V., Yakimov M.M.;
RT "Discovery of first anaerobic lithoheterotrophic haloarchae widely
RT represented in hypersaline habitats.";
RL Submitted (AUG-2016) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:APE96037.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HSR6 {ECO:0000313|EMBL:APE96037.1};
RX PubMed=28106880; DOI=10.1038/ismej.2016.203;
RA Sorokin D.Y., Messina E., Smedile F., Roman P., Damste J.S.S., Ciordia S.,
RA Mena M.C., Ferrer M., Golyshin P.N., Kublanov I.V., Samarov N.I.,
RA Toshchakov S.V., La Cono V., Yakimov M.M.;
RT "Discovery of anaerobic lithoheterotrophic haloarchaea, ubiquitous in
RT hypersaline habitats.";
RL ISME J. 11:1245-1260(2017).
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DR EMBL; CP016070; AOW80699.1; -; Genomic_DNA.
DR EMBL; CP016804; APE96037.1; -; Genomic_DNA.
DR RefSeq; WP_070365374.1; NZ_CP016804.1.
DR AlphaFoldDB; A0A1D8S5R8; -.
DR STRING; 1873524.HSR6_1596; -.
DR GeneID; 30418124; -.
DR KEGG; halh:HTSR_1525; -.
DR KEGG; hhsr:HSR6_1596; -.
DR PATRIC; fig|1855411.3.peg.1528; -.
DR OrthoDB; 106505at2157; -.
DR Proteomes; UP000185608; Chromosome.
DR Proteomes; UP000186165; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR031803; BAT_GAF/HTH-assoc.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR007050; HTH_bacterioopsin.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR34236; DIMETHYL SULFOXIDE REDUCTASE TRANSCRIPTIONAL ACTIVATOR; 1.
DR PANTHER; PTHR34236:SF1; DIMETHYL SULFOXIDE REDUCTASE TRANSCRIPTIONAL ACTIVATOR; 1.
DR Pfam; PF15915; BAT; 1.
DR Pfam; PF13185; GAF_2; 1.
DR Pfam; PF04967; HTH_10; 1.
DR Pfam; PF13426; PAS_9; 1.
DR SMART; SM00086; PAC; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000186165};
KW Transcription {ECO:0000256|ARBA:ARBA00023015};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..28
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 99..144
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 170..224
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT COILED 215..252
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 623 AA; 69075 MW; E775A81EBD3634EA CRC64;
MFPLDGLVIL TSIGLRLIGL GYSVYLLYQV EDRRFGFFTL MLGLMASRQI LSYQTGTSGI
DELPGLVVSV LAVLTVYYLS EYVEQEQTIR ETIEATNDRL RTFEKAIEHA GHAIFITEPD
GTVTYANRAV ESVTGYTRGE VIGRDPSMWK SGYHDPAFYR EMWETIEAGS IWEGQIVNET
KSGAEVWVDM TIAPIVGDSG AVEKYVAVDT DITDRRERKE QITEQKERLA TLNRTNEVLR
DINRELVEAD SRADIETAVV EQFANSDQYA FACLSDQAVD AEMIRPRAKA GIDDTDMEEL
IAAINDLEGA DPLRTAARTG TVQISSCADP EAEWCDPWLD RGYRATVAIP LTYGDRQYGV
LCIGTEAGDA FEDIETAVFA ELGETIGYAI NAVESKEALL TDSVTEIEFQ VTDPSYFPVA
LTADGGSMEL TWMTPGTGDT LVQYFTVTGL QPEAIREYVA GTPSLTAVDI LTEDDAELQV
RFEVQESTLA RPIGEAGGDL RHIEAADGRA RLTVHLSPNA NVRAVIEGLQ TDHPSIELRA
RRETERPAPT AEEVRTTIEE SLTDRQREAL HTAFIAGFFD WPRENSGEEI AETMAISQST
FLQHLRTAQK KVFAVLLRDE PVR
//
