ID   A0A1D8T242_9NOCA        Unreviewed;       781 AA.
AC   A0A1D8T242;
DT   15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT   15-FEB-2017, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=Glycosyl hydrolase {ECO:0000313|EMBL:AOW91758.1};
GN   ORFNames=BFN03_01115 {ECO:0000313|EMBL:AOW91758.1};
OS   Rhodococcus sp. WMMA185.
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC   Rhodococcus.
OX   NCBI_TaxID=679318 {ECO:0000313|EMBL:AOW91758.1, ECO:0000313|Proteomes:UP000178767};
RN   [1] {ECO:0000313|EMBL:AOW91758.1, ECO:0000313|Proteomes:UP000178767}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WMMA185 {ECO:0000313|EMBL:AOW91758.1,
RC   ECO:0000313|Proteomes:UP000178767};
RA   Bugni T.S., Adnani N., Braun D., Chevrette M., McDonald B., Rajski S.;
RT   "Draft Genome of Rhodococcus sp. WMMA185.";
RL   Submitted (AUG-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 65 family.
CC       {ECO:0000256|ARBA:ARBA00006768}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP017014; AOW91758.1; -; Genomic_DNA.
DR   RefSeq; WP_070377460.1; NZ_CP017014.1.
DR   AlphaFoldDB; A0A1D8T242; -.
DR   STRING; 679318.BFN03_01115; -.
DR   KEGG; rhw:BFN03_01115; -.
DR   OrthoDB; 9816160at2; -.
DR   Proteomes; UP000178767; Chromosome.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0016798; F:hydrolase activity, acting on glycosyl bonds; IEA:UniProtKB-KW.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 1.50.10.10; -; 1.
DR   Gene3D; 2.70.98.40; Glycoside hydrolase, family 65, N-terminal domain; 1.
DR   Gene3D; 2.60.420.10; Maltose phosphorylase, domain 3; 1.
DR   InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR   InterPro; IPR012341; 6hp_glycosidase-like_sf.
DR   InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR   InterPro; IPR005194; Glyco_hydro_65_C.
DR   InterPro; IPR005195; Glyco_hydro_65_M.
DR   InterPro; IPR005196; Glyco_hydro_65_N.
DR   InterPro; IPR037018; Glyco_hydro_65_N_sf.
DR   InterPro; IPR017045; Malt_Pase/Glycosyl_Hdrlase.
DR   PANTHER; PTHR11051; GLYCOSYL HYDROLASE-RELATED; 1.
DR   PANTHER; PTHR11051:SF13; GLYCOSYL TRANSFERASE-RELATED; 1.
DR   Pfam; PF03633; Glyco_hydro_65C; 1.
DR   Pfam; PF03632; Glyco_hydro_65m; 1.
DR   Pfam; PF03636; Glyco_hydro_65N; 1.
DR   PIRSF; PIRSF036289; Glycosyl_hydrolase_malt_phosph; 1.
DR   SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR   SUPFAM; SSF48208; Six-hairpin glycosidases; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW   Hydrolase {ECO:0000313|EMBL:AOW91758.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000178767}.
FT   DOMAIN          16..269
FT                   /note="Glycoside hydrolase family 65 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF03636"
FT   DOMAIN          326..679
FT                   /note="Glycoside hydrolase family 65 central catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF03632"
FT   DOMAIN          688..749
FT                   /note="Glycoside hydrolase family 65 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF03633"
FT   ACT_SITE        487
FT                   /note="Proton donor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR036289-50"
FT   BINDING         360..361
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR036289-51"
FT   BINDING         591..592
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR036289-51"
SQ   SEQUENCE   781 AA;  86257 MW;  B05642AB15C0218C CRC64;
     MSELGYQISP WQLCWSGLDL EALRFTESTF ALSNGHIGIR GTFEEGEPRG LPGTYLNGYY
     EQRPLPYAEA GYGYPEDGQT VVNVTDGSII RLLVADEPLD MRYGSATAHE RVLDFRSGTL
     RRTTDWTSPT GRKVRIRSER LVSFTSRAIA AIRYEVEPLD DDIELVLQSD LLANERLPVR
     TDDPRVAAAL HHPLVADFAA SHDFRAVLAH HTRASGLRMA AGMDHEIELP TNGRCSIETE
     EDLARLTVAV NVPKGQRLKM TKFLAYGWSA HRSTPALRGQ VEGALAGALE IGWATLLRRQ
     REYLDLFWET ADIEIAGDAE LQQAVRFGLF HVLQAGARGE TRAISAKGLT GPGYDGHAFW
     DTEAFVLPLL TYTVPDSARD ALRWRHSTLD KAKNRAAQLG QAGAVFPWRS INGDECSGYW
     PAGTAAFHVG AAVAAATSRY LAATGDEEFE SECGATLLIE TARLWTSLGH HNSRGEFRID
     GVTGPDEYTA VADNNVYTNL MAQKNMHDAA AVCERRPDLA REHGVDDEES SRWRDAGARM
     RIPFDEALGV HQQSEGFTHH AEWDFEGTPP ENYPLLLNYP YFDLYRKQVV KQADLVLAMY
     FRGDAFTDEQ KMANFAYYEA LTVRDSSLSA CAQSVMAAEV GQLQLAYDYL AEAALTDLHD
     LHSNVENGLH IASLAGTWMA CVAGFGGMRD HGGNITFAPR IPPQLANMNF RMTVRGSQIH
     VDIRANSATY RLRSGRPVKL AHHGKTFTLG SSPVTKPIPE LPTIPPVRQP YGRAPVRRGG
     S
//