ID A0A1D8T4Y5_9NOCA Unreviewed; 394 AA.
AC A0A1D8T4Y5;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=Thiamine pyrophosphokinase {ECO:0000313|EMBL:AOW92751.1};
GN ORFNames=BFN03_08755 {ECO:0000313|EMBL:AOW92751.1};
OS Rhodococcus sp. WMMA185.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Rhodococcus.
OX NCBI_TaxID=679318 {ECO:0000313|EMBL:AOW92751.1, ECO:0000313|Proteomes:UP000178767};
RN [1] {ECO:0000313|EMBL:AOW92751.1, ECO:0000313|Proteomes:UP000178767}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WMMA185 {ECO:0000313|EMBL:AOW92751.1,
RC ECO:0000313|Proteomes:UP000178767};
RA Bugni T.S., Adnani N., Braun D., Chevrette M., McDonald B., Rajski S.;
RT "Draft Genome of Rhodococcus sp. WMMA185.";
RL Submitted (AUG-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP017014; AOW92751.1; -; Genomic_DNA.
DR RefSeq; WP_070378690.1; NZ_CP017014.1.
DR AlphaFoldDB; A0A1D8T4Y5; -.
DR STRING; 679318.BFN03_08755; -.
DR KEGG; rhw:BFN03_08755; -.
DR OrthoDB; 5169996at2; -.
DR Proteomes; UP000178767; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0004788; F:thiamine diphosphokinase activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0009229; P:thiamine diphosphate biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.10240; Thiamin pyrophosphokinase, catalytic domain; 1.
DR InterPro; IPR047795; Put_SteA-like.
DR InterPro; IPR022215; SteA-like_C.
DR InterPro; IPR036759; TPK_catalytic_sf.
DR NCBIfam; NF040608; division_SteA; 1.
DR Pfam; PF12555; SteA-like_C; 1.
DR SUPFAM; SSF63999; Thiamin pyrophosphokinase, catalytic domain; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:AOW92751.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000178767};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 349..368
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 335..386
FT /note="SteA-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF12555"
SQ SEQUENCE 394 AA; 41631 MW; 016D017BC0110D36 CRC64;
MKLPALRSRN TQPLPGVSGI ARVDRNTDKL LRRVGPGDVV VLDELDLDRR TADALVKAGV
LAVINASPSI SGRYPNLGPE VIVSNGIALV DSVGTEVFKN IKDGGKVRVH EGAVYSGERR
IAKGDAQTEA EISDRMIEAK TGLVDHLEAF SGNTIEFIRT ESPLLIDSVG VPDVDVDMKE
RHVVIVSDGP DHVSDLKNLK PFIKEYSPIL IGVGTGADAL KTAGYRPDLI VGDPEAISSA
TLKSGAEVVL PADQDGHAPG LSRIQDLGIG AMTFPASGSP SDLALLLADH HGAALIVTVG
STVSLDEFFD RGRRDINPSA FMTRLKVGPK LVDAKAVATL YRSRVSGGAI ALLILAALVA
VIVALAMSNV GGEVLDWAVA TWDSFVLWVQ GFFK
//
