ID A0A1D9FNU2_9CLOT Unreviewed; 453 AA.
AC A0A1D9FNU2;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Thioether cross-link-forming SCIFF peptide maturase {ECO:0000313|EMBL:AOY76945.1};
GN ORFNames=BJL90_14410 {ECO:0000313|EMBL:AOY76945.1};
OS Clostridium formicaceticum.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1497 {ECO:0000313|EMBL:AOY76945.1, ECO:0000313|Proteomes:UP000177894};
RN [1] {ECO:0000313|EMBL:AOY76945.1, ECO:0000313|Proteomes:UP000177894}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 27076 {ECO:0000313|EMBL:AOY76945.1,
RC ECO:0000313|Proteomes:UP000177894};
RA Bao T., Cheng C., Zhao J., Yang S.-T., Wang J., Wang M.;
RT "Complete Genome Sequence of Acetogen Clostridium formicoaceticum ATCC
RT 27076.";
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- SIMILARITY: Belongs to the radical SAM superfamily. Anaerobic
CC sulfatase-maturating enzyme family. {ECO:0000256|ARBA:ARBA00023601}.
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DR EMBL; CP017603; AOY76945.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1D9FNU2; -.
DR STRING; 1497.BJL90_14410; -.
DR KEGG; cfm:BJL90_14410; -.
DR Proteomes; UP000177894; Chromosome.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR CDD; cd01335; Radical_SAM; 1.
DR CDD; cd21124; SPASM_CteB-like; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR023885; 4Fe4S-binding_SPASM_dom.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR000385; MoaA_NifB_PqqE_Fe-S-bd_CS.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR024025; SCIFF_rSAM_maturase.
DR InterPro; IPR047602; SPASM_CteB-like.
DR InterPro; IPR023867; Sulphatase_maturase_rSAM.
DR NCBIfam; TIGR04085; rSAM_more_4Fe4S; 1.
DR NCBIfam; TIGR03974; rSAM_six_Cys; 1.
DR PANTHER; PTHR43273; ANAEROBIC SULFATASE-MATURATING ENZYME HOMOLOG ASLB-RELATED; 1.
DR PANTHER; PTHR43273:SF8; RADICAL SAM PROTEIN-RELATED; 1.
DR Pfam; PF13353; Fer4_12; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR Pfam; PF13186; SPASM; 1.
DR SFLD; SFLDG01072; dehydrogenase_like; 1.
DR SFLD; SFLDG01384; thioether_bond_formation_requi; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS01305; MOAA_NIFB_PQQE; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 90..320
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 453 AA; 51947 MW; 48239C86AFE1CF6B CRC64;
MVMIHKFSQG NVNIVLDVNS GAVHVVDQLV YDVLDYYPEN TKEKIMPLLK DKYSDEKISE
AVDEIDSLIS NGLLFSKENY LQHEAFQSRE TVVKALCLHI AHDCNIRCKY CFASQGDFKG
ERSLMTPEVG KKALDFLLEN SGRRRNLEVD FFGGEPLMNF EVIKEIVDYG RQQEKKYEKN
IRFTITTNGV LLNKDTMDYI NKNMHNVVLS IDGRKEINDY MRYTINGGGT YDIIIPKLLE
MAALRNHENY YVRGTFTSHN LDFAADVLHL ADLGFKHISV EPVVATEEND YAINEEDLPQ
VLKEYEYLAE ECIKRNKAGK GFNFFHFMID LNQGPCVIKR LLGCGAGAEY LAVTPEGELY
PCHQFVGDEN FKLGDVNDNS LDMSMYKEFS NAHVYHKEAC QQCWAKFYCS GGCHANAYNF
NKSIYTPYKV GCEMEKKRIE CALMIQARLM EEV
//
