ID A0A1D9H7I5_9BURK Unreviewed; 231 AA.
AC A0A1D9H7I5;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=D-lactate dehydratase {ECO:0000256|ARBA:ARBA00013134};
DE EC=4.2.1.130 {ECO:0000256|ARBA:ARBA00013134};
GN ORFNames=BKK79_29500 {ECO:0000313|EMBL:AOY95822.1};
OS Cupriavidus sp. USMAA2-4.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Cupriavidus.
OX NCBI_TaxID=876364 {ECO:0000313|EMBL:AOY95822.1, ECO:0000313|Proteomes:UP000178101};
RN [1] {ECO:0000313|EMBL:AOY95822.1, ECO:0000313|Proteomes:UP000178101}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=USMAA2-4 {ECO:0000313|EMBL:AOY95822.1,
RC ECO:0000313|Proteomes:UP000178101};
RA Abdullah A.A.-A., Shafie N.A.H., Lau N.S.;
RT "Complete genome sequences of three Cupriavidus strains isolated from
RT various Malaysian environments.";
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + methylglyoxal = (R)-lactate + H(+);
CC Xref=Rhea:RHEA:27754, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:16004, ChEBI:CHEBI:17158; EC=4.2.1.130;
CC Evidence={ECO:0000256|ARBA:ARBA00001524};
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DR EMBL; CP017749; AOY95822.1; -; Genomic_DNA.
DR RefSeq; WP_071039585.1; NZ_CP017749.1.
DR AlphaFoldDB; A0A1D9H7I5; -.
DR STRING; 876364.BKK79_29500; -.
DR KEGG; cuu:BKK79_29500; -.
DR Proteomes; UP000178101; Chromosome 2.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.
DR CDD; cd03141; GATase1_Hsp31_like; 1.
DR Gene3D; 3.40.50.880; -; 1.
DR InterPro; IPR029062; Class_I_gatase-like.
DR InterPro; IPR002818; DJ-1/PfpI.
DR PANTHER; PTHR48094:SF11; GLUTATHIONE-INDEPENDENT GLYOXALASE HSP31-RELATED; 1.
DR PANTHER; PTHR48094; PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED; 1.
DR Pfam; PF01965; DJ-1_PfpI; 1.
DR SUPFAM; SSF52317; Class I glutamine amidotransferase-like; 1.
PE 4: Predicted;
KW Glutamine amidotransferase {ECO:0000313|EMBL:AOY95822.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000178101};
KW Stress response {ECO:0000256|ARBA:ARBA00023016};
KW Transferase {ECO:0000313|EMBL:AOY95822.1}.
FT DOMAIN 28..225
FT /note="DJ-1/PfpI"
FT /evidence="ECO:0000259|Pfam:PF01965"
SQ SEQUENCE 231 AA; 24478 MW; D3F76F512BE97D1E CRC64;
MSQRILMIVT SNHRMGAYDK PTGLWAEELA TPWYALVDAG VAIELASPAG GPAPIDPGSI
QPEGRNEAAV ARFLADPDLR ARVAATSKTA DLDMAGFDAV FFPGGHGTMW DLPGDAGVKR
LVEQAEAAGK IISSVCHGAA GLVSARRADG RPLVADRTVN AFTNAEEIEV GLQEVVPFLL
ESRLRELGGR FECAPNWHPF AVRDGNLITG QNPQSSERVA REVLQALGLA A
//
