ID A0A1D9P0Y1_9FIRM Unreviewed; 408 AA.
AC A0A1D9P0Y1;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=threonine ammonia-lyase {ECO:0000256|ARBA:ARBA00012096};
DE EC=4.3.1.19 {ECO:0000256|ARBA:ARBA00012096};
GN ORFNames=bhn_I1252 {ECO:0000313|EMBL:AOZ96286.1};
OS Butyrivibrio hungatei.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC Butyrivibrio.
OX NCBI_TaxID=185008 {ECO:0000313|EMBL:AOZ96286.1, ECO:0000313|Proteomes:UP000179284};
RN [1] {ECO:0000313|Proteomes:UP000179284}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MB2003 {ECO:0000313|Proteomes:UP000179284};
RA Palevich N., Kelly W.J., Leahy S.C., Altermann E., Rakonjac J.,
RA Attwood G.T.;
RT "The complete genome sequence of the rumen bacterium Butyrivibrio hungatei
RT MB2003.";
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
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DR EMBL; CP017831; AOZ96286.1; -; Genomic_DNA.
DR RefSeq; WP_071175988.1; NZ_CP017831.1.
DR AlphaFoldDB; A0A1D9P0Y1; -.
DR KEGG; bhu:bhn_I1252; -.
DR OrthoDB; 9811476at2; -.
DR Proteomes; UP000179284; Chromosome i.
DR GO; GO:0004794; F:L-threonine ammonia-lyase activity; IEA:UniProtKB-EC.
DR GO; GO:0009097; P:isoleucine biosynthetic process; IEA:UniProtKB-KW.
DR GO; GO:0006567; P:threonine catabolic process; IEA:InterPro.
DR CDD; cd04886; ACT_ThrD-II-like; 1.
DR CDD; cd01562; Thr-dehyd; 1.
DR Gene3D; 3.40.50.1100; -; 2.
DR InterPro; IPR045865; ACT-like_dom_sf.
DR InterPro; IPR002912; ACT_dom.
DR InterPro; IPR044561; ACT_ThrD-II-like.
DR InterPro; IPR005789; Thr_deHydtase_catblc.
DR InterPro; IPR001926; TrpB-like_PALP.
DR InterPro; IPR036052; TrpB-like_PALP_sf.
DR NCBIfam; TIGR01127; ilvA_1Cterm; 1.
DR PANTHER; PTHR48078:SF6; ACT DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR48078; THREONINE DEHYDRATASE, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF00291; PALP; 1.
DR SUPFAM; SSF55021; ACT-like; 1.
DR SUPFAM; SSF53686; Tryptophan synthase beta subunit-like PLP-dependent enzymes; 1.
DR PROSITE; PS51671; ACT; 1.
PE 4: Predicted;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00023304};
KW Branched-chain amino acid biosynthesis {ECO:0000256|ARBA:ARBA00023304};
KW Isoleucine biosynthesis {ECO:0000256|ARBA:ARBA00022624};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Reference proteome {ECO:0000313|Proteomes:UP000179284}.
FT DOMAIN 330..408
FT /note="ACT"
FT /evidence="ECO:0000259|PROSITE:PS51671"
SQ SEQUENCE 408 AA; 44327 MW; D22F3BEA4C2954E5 CRC64;
MADDSKMTLD KFEEAYEDVK KVTLETKLIY SDYFSNLSGN KVYLKPENLQ RTGAYKVRGA
YYKITTLSDE ERKKGLITAS AGNHAQGVAY AAKAYGVKAT IVMPTSTPLI KVNRTKALGA
EVVLHGNVFD EAYEHACKLA EENGYTMVHP FDDLDVATGQ GTIAMEIIKE LPTVDYILVP
IGGGGLATGV STLAKLLNPK IKVIGVEPAG ANCMQESLKA GHVVTLPTVN TIADGTAVKK
PGEKIFPYIS KNIDEIITVP DEDLVVSFLD MVENHKMVVE NSGLLSVAAL KQLDVKDKKV
ACVLSGGNMD IITMSSVVQQ GLIMRDRIFT VSVLLPDKPG ELSRVSGIIA DVNGNVIKLE
HNQFVSINRS AAVELRITLE AFGTEHKEQI MNALNENGYQ PRIVRTNI
//
