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Database: UniProt
Entry: A0A1D9PCU8_9FLAO
LinkDB: A0A1D9PCU8_9FLAO
Original site: A0A1D9PCU8_9FLAO 
ID   A0A1D9PCU8_9FLAO        Unreviewed;       475 AA.
AC   A0A1D9PCU8;
DT   15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT   15-FEB-2017, sequence version 1.
DT   13-FEB-2019, entry version 19.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01081161};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=BIW12_11140 {ECO:0000313|EMBL:AOZ99935.1};
OS   Flavobacterium commune.
OC   Bacteria; Bacteroidetes; Flavobacteriia; Flavobacteriales;
OC   Flavobacteriaceae; Flavobacterium.
OX   NCBI_TaxID=1306519 {ECO:0000313|EMBL:AOZ99935.1, ECO:0000313|Proteomes:UP000178198};
RN   [1] {ECO:0000313|EMBL:AOZ99935.1, ECO:0000313|Proteomes:UP000178198}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PK15 {ECO:0000313|EMBL:AOZ99935.1,
RC   ECO:0000313|Proteomes:UP000178198};
RA   Ekwe A., Kim S.B.;
RT   "Complete Genome Sequence of Flavobacterium sp. PK15.";
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756121}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS01082709}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; CP017774; AOZ99935.1; -; Genomic_DNA.
DR   RefSeq; WP_071185176.1; NZ_CP017774.1.
DR   KEGG; fcm:BIW12_11140; -.
DR   KO; K02313; -.
DR   OrthoDB; 219876at2; -.
DR   BioCyc; GCF_001857965:G1FBC-2250-MONOMER; -.
DR   Proteomes; UP000178198; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   Gene3D; 3.30.300.180; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR038454; DnaA_N_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756129};
KW   Complete proteome {ECO:0000313|Proteomes:UP000178198};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS01082702};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00756116};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01082706};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756117};
KW   Reference proteome {ECO:0000313|Proteomes:UP000178198}.
FT   DOMAIN      172    302       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      383    452       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     180    187       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   475 AA;  54408 MW;  ECBF197E43BCC125 CRC64;
     MNKTAQSVWD NCLSFIKDNI QDQAYKTWFE PIKSVELTDN ALYIQVPSKF FYEWLEEHYV
     KLLKVALTKE LGKNAKLLYK IKMENTYGNK QPFTEQLPSA NRSPVKPQNV DAPLKNLDPE
     LKNPFVIPGI RNLKIESQLN ANYSFDNFLE GDSNRLARSA GMAVANKPGG TSFNPLLIFG
     GVGLGKTHLA HAIGVEIKDK YPEKTVLYIS AEIFTQQYID SVKKNNRNDF IHFYQLIDVL
     IIDDVQFLSG KSGTQDVFFH IFNYLHQNGK QVILTSDKAP VDMQDIEQRL LSRFKWGLSA
     ELHQPDYETR ISILKNILYR DGVEMPDEII EYVARNIKSN VRELEGAIIS LIAQSSFNKK
     EVTIELAKSV VEKFVKNVKR EISIDYIQKI VSDYFQLDVE TLQSKTRKRH VVQARQLAMF
     FAKKFTKSSL ANIGSQIGDR DHATVLHACK TVDNLVATDK QFKKFVEDIH KKLTL
//
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