ID   A0A1E1F3M8_9SPHN        Unreviewed;      1054 AA.
AC   A0A1E1F3M8;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Hydrophobic/amphiphilic exporter-1 {ECO:0000313|EMBL:BAV65125.1};
GN   ORFNames=SCLO_1020850 {ECO:0000313|EMBL:BAV65125.1};
OS   Sphingobium cloacae.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC   Sphingomonadaceae; Sphingobium.
OX   NCBI_TaxID=120107 {ECO:0000313|EMBL:BAV65125.1, ECO:0000313|Proteomes:UP000218272};
RN   [1] {ECO:0000313|EMBL:BAV65125.1, ECO:0000313|Proteomes:UP000218272}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 10874 {ECO:0000313|EMBL:BAV65125.1,
RC   ECO:0000313|Proteomes:UP000218272};
RA   Ootsuka M., Nishizawa T., Ohta H.;
RT   "Complete Genome Sequence of the Nonylphenol-Degrading Bacterium
RT   Sphingobium cloacae JCM 10874T.";
RL   Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; AP017655; BAV65125.1; -; Genomic_DNA.
DR   RefSeq; WP_066520378.1; NZ_AP017655.1.
DR   AlphaFoldDB; A0A1E1F3M8; -.
DR   KEGG; sclo:SCLO_1020850; -.
DR   OrthoDB; 9806532at2; -.
DR   Proteomes; UP000218272; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR   Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR   Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   InterPro; IPR027463; AcrB_DN_DC_subdom.
DR   InterPro; IPR001036; Acrflvin-R.
DR   PANTHER; PTHR32063; -; 1.
DR   PANTHER; PTHR32063:SF77; ACR FAMILY TRANSPORT PROTEIN; 1.
DR   Pfam; PF00873; ACR_tran; 1.
DR   PRINTS; PR00702; ACRIFLAVINRP.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000218272};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        335..354
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        361..378
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        390..412
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        432..452
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        464..491
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        542..566
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        865..884
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        891..911
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        917..942
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        963..982
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        994..1023
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   1054 AA;  113544 MW;  736AA903019E52FC CRC64;
     MSFRNISAWA IRNPTSPLVL FAALLLAGLA SFGRMDVNQQ PDVSFPMASV TVLQPGAAPP
     ELETQVTQRV EAAVRAISGV DEITSFVSEG QSLTNVQFEI GTPVDRAVND VKNAVDQIRS
     DLPEGILEPQ VKRVDIDGGP IAYFGAEATD MTLEELSWYV DNTVAKRLLA VPGMAAVARG
     GGVSREIRVI LDPAKLQSHG VTAAQVNQQL QQVNLNAAGG RTEIAGSEQA IRVLGNAKNA
     HALGQTQISI PGDRTVKLAD LAEVRDMYAE QRSLALMNGR QVTSFRLEKA KGASDVTVYD
     EAMKVLDTLR QENPKVHFKQ LYTSVDYTKS QYHSAMQAMI EGAVLAVVIV FLFLRDWRAT
     MISALAIPLS AIPAFWFMDM MGFTLNMTSL LALSLVAGVL VDDAIVEIEN IVRHMRMGKT
     AYQASIDAAD EIGLAVLATT MAIVAVFLPV GLMPGLTGQF FKQFGLTVVV AVLLSLAVAR
     LITPMVAAYF LKAHGEEKHG EGWLMDRYMG VLHWSLDQRR AIAHRAKGGI ARYTAWLRDH
     RIWTVGLGLL AFLSTIVAFG TLPMSFQPTI DTDFSQVQIE TVPGSTLQQT TAITRRVADM
     LAADKDVVEA AFASINPTEA QIFLTLRKDR PISSVEWERK VAPQFQQVAD ARVNFQSQSG
     GGFGRDIVIM LGSDDPELLE HTANKLVSEM AGVREIRGAR VHGDMQRPEI VIKPRFDLAA
     SMGVTTAALS NTIRVATIGE IDQNTAKFSL SDRQIPIRVA VQEGSRRDMA TIANMPVPTI
     SGGSVPLKVV ADIEFGSGPT EIRRYNQIRR VVVGADLAPG IVTSQAMAKI NALPTMKAIL
     GGKIQGLQKI NAGDSKFEAE MLQNFVVAVV SGVLLVLAVL VLLYKRVMPP FVNLGSLLLA
     PLGGALALHL TGNPLSMPVF IGLLMLLGIV AKNSILVIDF ALEEMDKGVP KFEAIVDAGH
     KRAQPIVMTT VAMVAGMMPT ALSLGGDGAW RAPMGITVIG GLLLSTLLTL VIVPATFSLA
     LGVEEWIGPR LSRRLLTYKP GDDKAHAGQT QPAE
//