ID A0A1E1K900_9HELO Unreviewed; 553 AA.
AC A0A1E1K900;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Importin subunit alpha {ECO:0000256|PIRNR:PIRNR005673};
GN ORFNames=RCO7_10095 {ECO:0000313|EMBL:CZS94472.1};
OS Rhynchosporium commune.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Helotiales; Ploettnerulaceae; Rhynchosporium.
OX NCBI_TaxID=914237 {ECO:0000313|EMBL:CZS94472.1, ECO:0000313|Proteomes:UP000178129};
RN [1] {ECO:0000313|EMBL:CZS94472.1, ECO:0000313|Proteomes:UP000178129}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UK7 {ECO:0000313|EMBL:CZS94472.1,
RC ECO:0000313|Proteomes:UP000178129};
RA Ploux O.;
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the importin alpha family.
CC {ECO:0000256|ARBA:ARBA00010394, ECO:0000256|PIRNR:PIRNR005673}.
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DR EMBL; FJUW01000008; CZS94472.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1E1K900; -.
DR STRING; 914237.A0A1E1K900; -.
DR InParanoid; A0A1E1K900; -.
DR OrthoDB; 916229at2759; -.
DR Proteomes; UP000178129; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0061608; F:nuclear import signal receptor activity; IEA:InterPro.
DR GO; GO:0006606; P:protein import into nucleus; IEA:InterPro.
DR Gene3D; 1.20.5.690; Importin-alpha, importin-beta-binding domain; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR032413; Arm_3.
DR InterPro; IPR000225; Armadillo.
DR InterPro; IPR002652; Importin-a_IBB.
DR InterPro; IPR036975; Importin-a_IBB_sf.
DR InterPro; IPR024931; Importin_alpha.
DR PANTHER; PTHR23316; IMPORTIN ALPHA; 1.
DR PANTHER; PTHR23316:SF71; IMPORTIN SUBUNIT ALPHA; 1.
DR Pfam; PF00514; Arm; 8.
DR Pfam; PF16186; Arm_3; 1.
DR Pfam; PF01749; IBB; 1.
DR PIRSF; PIRSF005673; Importin_alpha; 1.
DR SMART; SM00185; ARM; 8.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50176; ARM_REPEAT; 3.
DR PROSITE; PS51214; IBB; 1.
PE 3: Inferred from homology;
KW Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW ECO:0000256|PIRNR:PIRNR005673};
KW Reference proteome {ECO:0000313|Proteomes:UP000178129};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR005673}.
FT DOMAIN 1..58
FT /note="IBB"
FT /evidence="ECO:0000259|PROSITE:PS51214"
FT REPEAT 125..167
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 167..209
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 337..369
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REGION 1..79
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 523..553
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..49
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 527..544
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 553 AA; 60458 MW; 5424E3F6CC826F9F CRC64;
MAERYIPEHR RTTFKAKNTF KPEELRRRRE EQQVEIRKAK REENLAKRRG ITGGDGSRPG
ASLGAEPDSD DDTAPTESQL NEDLPQMVAG VFSEQIDLQI QATTKFRKLL SKERNPPIEE
VIKTGVVSRF VVFLRSPHTL VQFEAAWALT NIASGSAQQT QVVIEAGAVP IFVELLGSHE
PDVREQAVWA LGNIAGDSPS CRDYVLSCGA LKPLLNLLGD SRKLSMLRNA TWTLSNFCRG
KTPQPDWNTQ ILPALPVLAK LVYSLDDEVL IDACWAISYL SDGANDKIQA VIEAGIPRRL
VELLMHASTS VQTPALRSVG NIVTGDDVQT QVIINCGALP ALLSLLSSGK DGIRKEACWT
ISNVTAGNST QIQAVIDANI IPPLIHLLSN GDLKTRKEAC WAISNATSGG LQKPEQIRYL
VNQGCIKPLC DLLACPDNKI IQVALDGLEN ILKVGEMDKD AAGEGQESIN RYALFIEECQ
GMEKIHDCQT NANEEIYMKA YNMIEKYFSD EDDVAEVEEG VTKPDGTFGF GNSTAPQGSG
FSFAGPNGDS MDM
//
