ID A0A1E1KCX7_9HELO Unreviewed; 488 AA.
AC A0A1E1KCX7;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=poly(A)-specific ribonuclease {ECO:0000256|ARBA:ARBA00012161};
DE EC=3.1.13.4 {ECO:0000256|ARBA:ARBA00012161};
GN ORFNames=RCO7_08804 {ECO:0000313|EMBL:CZS95851.1};
OS Rhynchosporium commune.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Helotiales; Ploettnerulaceae; Rhynchosporium.
OX NCBI_TaxID=914237 {ECO:0000313|EMBL:CZS95851.1, ECO:0000313|Proteomes:UP000178129};
RN [1] {ECO:0000313|EMBL:CZS95851.1, ECO:0000313|Proteomes:UP000178129}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UK7 {ECO:0000313|EMBL:CZS95851.1,
RC ECO:0000313|Proteomes:UP000178129};
RA Ploux O.;
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Exonucleolytic cleavage of poly(A) to 5'-AMP.; EC=3.1.13.4;
CC Evidence={ECO:0000256|ARBA:ARBA00001663};
CC -!- SIMILARITY: Belongs to the CAF1 family.
CC {ECO:0000256|ARBA:ARBA00008372}.
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DR EMBL; FJUW01000011; CZS95851.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1E1KCX7; -.
DR STRING; 914237.A0A1E1KCX7; -.
DR InParanoid; A0A1E1KCX7; -.
DR OrthoDB; 341493at2759; -.
DR Proteomes; UP000178129; Unassembled WGS sequence.
DR GO; GO:0030014; C:CCR4-NOT complex; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0004535; F:poly(A)-specific ribonuclease activity; IEA:UniProtKB-EC.
DR GO; GO:0006402; P:mRNA catabolic process; IEA:UniProt.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR039637; CNOT7/CNOT8/Pop2.
DR InterPro; IPR006941; RNase_CAF1.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR10797; CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT; 1.
DR PANTHER; PTHR10797:SF0; CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 7; 1.
DR Pfam; PF04857; CAF1; 2.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000178129};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT REGION 1..44
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 428..488
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 13..44
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 428..472
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 488 AA; 53329 MW; 62D59262E3C2B429 CRC64;
MPPPMQRFGG APNNLASHYQ QYPSHSQSHN AGLPPPSLTS NPGFMNANSM SNAFSMNGNA
MSLSGGFGGA GLGIPGGTGL ASQAAQMGFA NANNQGHNGM DHQVRVTGNK TRTRDVWAGN
LKEEMAILRC LVDKFPYIAM DTEFPGLVAR PMGSFNGKSD YHYQCLRCNV DLLKILQLGI
SLFTEDGDSP PATMSAANLG LDTTQDETRK YANAMVQLPT TWQFNFKFSL EEDMYSEQHI
KAAELTGVDF PRLSTEGIEP DDFGSLFMSS GLVCDEDVYW VSFHGGYDFG YLMKLFLIDP
LPDDEFEFDR LMKKFFPSIY DIKFLMKYAI RQHAMGHATP LDGQSSEVLQ KFEQKSTLDI
LAESLKVKRQ GVAHQAGSDS LWTGKVFFKM RERIFNGELS EEHIGKVWGL GFTEYPIPNA
HIHSAPTYQH QQENVTPGQN GYTNGGPSTP NTGNAGLATP GHNSNGGSMG PQTPGATGAF
GAFQYSSR
//
