ID   A0A1E1KYF6_9HELO        Unreviewed;       846 AA.
AC   A0A1E1KYF6;
DT   15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT   15-FEB-2017, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE            EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN   ORFNames=RCO7_11091 {ECO:0000313|EMBL:CZT02160.1};
OS   Rhynchosporium commune.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Helotiales; Ploettnerulaceae; Rhynchosporium.
OX   NCBI_TaxID=914237 {ECO:0000313|EMBL:CZT02160.1, ECO:0000313|Proteomes:UP000178129};
RN   [1] {ECO:0000313|EMBL:CZT02160.1, ECO:0000313|Proteomes:UP000178129}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UK7 {ECO:0000313|EMBL:CZT02160.1,
RC   ECO:0000313|Proteomes:UP000178129};
RA   Ploux O.;
RL   Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC         Evidence={ECO:0000256|ARBA:ARBA00001665};
CC   -!- SIMILARITY: Belongs to the helicase family. RAD25/XPB subfamily.
CC       {ECO:0000256|ARBA:ARBA00006637}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FJUW01000024; CZT02160.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1E1KYF6; -.
DR   STRING; 914237.A0A1E1KYF6; -.
DR   InParanoid; A0A1E1KYF6; -.
DR   OrthoDB; 1360679at2759; -.
DR   Proteomes; UP000178129; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR   GO; GO:0006367; P:transcription initiation at RNA polymerase II promoter; IEA:InterPro.
DR   CDD; cd18029; DEXHc_XPB; 1.
DR   CDD; cd18789; SF2_C_XPB; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR032438; ERCC3_RAD25_C.
DR   InterPro; IPR006935; Helicase/UvrB_N.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR001161; XPB/Ssl2.
DR   InterPro; IPR032830; XPB/Ssl2_N.
DR   NCBIfam; TIGR00603; rad25; 1.
DR   PANTHER; PTHR11274:SF0; GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE SUBUNIT XPB; 1.
DR   PANTHER; PTHR11274; RAD25/XP-B DNA REPAIR HELICASE; 1.
DR   Pfam; PF16203; ERCC3_RAD25_C; 1.
DR   Pfam; PF13625; Helicase_C_3; 1.
DR   Pfam; PF04851; ResIII; 1.
DR   PRINTS; PR00851; XRODRMPGMNTB.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:CZT02160.1};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:CZT02160.1};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022806,
KW   ECO:0000313|EMBL:CZT02160.1}; Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000178129}.
FT   DOMAIN          358..520
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          574..728
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
FT   REGION          1..56
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          258..277
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          774..795
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          810..846
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        10..45
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   846 AA;  95252 MW;  77C868C8EA4ED034 CRC64;
     MPPKRKAVSS VKGSNKTGKE SASSTPGPAT PRSIDDGGNS DNYVSAEESD ETEEETEIVK
     NAKSNLTVAK YHKKSATTQG RDSASYRFDG GNTDFSYLSL KPDHDNRPLW IDPLKGRIIC
     ESFSPLAAQA QDFLTTVAEP LSRPQYLHEY KLTPHSLYAA VSVGMTPNDI INVLNRLSKV
     PVPQEIREYI LGCTTSYGKV KLVLKNTKHY VESTDPEMLQ RLLRDEVIGP LRVQGTEELT
     TTSAPKMGAL VIPGTKNAAG VNQTTDQTKK PQDGENADQE DIFATLNEDD DEEELDAVHA
     FEIADDGVET IQKRCLELGL PVLEEYDFRN DEANATLDID LRPTAQIRDY QEKSLSKMFG
     NGRAKSGLIV LPCGAGKTLV GITAACTIKK GVIVLCTSSM SVVQWRQEFL KWSNINPNDV
     AVFTSDNKDK FSGNTGIIVT TYNMVAQKGK RSYDSQKMMD FLTKREWGLM ILDEVHVAPA
     HMFRRVTSII KTHSKLGLTA TLLREDDKIS DLNFLIGPKL YEANWMELAE QGHIARVQCA
     EVWCPMTTEF YSEYLKQSSK NKSLLWIMNP RKFQACQFLI DYHEKRGDKI IVFSDNVYAL
     KMYAQKLNKV FIYGETGNAE RLRILENFQH NENINTLFLS KIGDTSLDLP EATCLIQISS
     HFGSRRQEAQ RLGRILRAKR RNDEGFNAFF YSLVSKDTLE MVYSSKRQAF LVDQGYAFKV
     ITHLQGIESL PELAFTTAIE RRELLQNVMI HNETDESKYD YDDGDDLFHH VDKQGTKGVA
     KKGRKKAGAR RTAGTLSELA GGQDMAYVEM NKSKNRELKK PKESNPFFRK LQRENAKKKL
     AMEEDN
//