ID A0A1E2WH24_9NOSO Unreviewed; 323 AA.
AC A0A1E2WH24;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Cobalamin biosynthesis protein CobW {ECO:0000313|EMBL:ODG97710.1};
GN ORFNames=A4S05_12125 {ECO:0000313|EMBL:ODG97710.1};
OS Nostoc sp. KVJ20.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Nostocaceae; Nostoc.
OX NCBI_TaxID=457944 {ECO:0000313|EMBL:ODG97710.1, ECO:0000313|Proteomes:UP000094607};
RN [1] {ECO:0000313|EMBL:ODG97710.1, ECO:0000313|Proteomes:UP000094607}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KVJ20 {ECO:0000313|EMBL:ODG97710.1,
RC ECO:0000313|Proteomes:UP000094607};
RA Wen L., He K., Yang H.;
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. ZNG1
CC subfamily. {ECO:0000256|ARBA:ARBA00034320}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ODG97710.1}.
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DR EMBL; LSSA01000372; ODG97710.1; -; Genomic_DNA.
DR RefSeq; WP_069070079.1; NZ_KV757603.1.
DR AlphaFoldDB; A0A1E2WH24; -.
DR OrthoDB; 504781at2; -.
DR Proteomes; UP000094607; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd03112; CobW-like; 1.
DR Gene3D; 3.30.1220.10; CobW-like, C-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR036627; CobW-likC_sf.
DR InterPro; IPR011629; CobW-like_C.
DR InterPro; IPR003495; CobW/HypB/UreG_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13748:SF62; COBW DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR13748; COBW-RELATED; 1.
DR Pfam; PF02492; cobW; 1.
DR Pfam; PF07683; CobW_C; 1.
DR SMART; SM00833; CobW_C; 1.
DR SUPFAM; SSF90002; Hypothetical protein YjiA, C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT DOMAIN 228..322
FT /note="CobW C-terminal"
FT /evidence="ECO:0000259|SMART:SM00833"
SQ SEQUENCE 323 AA; 35762 MW; E3F3223C4E3F7C35 CRC64;
MVADVINNSV PVTVLTGYLG AGKTTLLNHI LTYEHGKKVA VIVNEFGEVG IDNQLIIDAD
EEIFEMNNGC ICCTVRGDLI RIIGNLMKRR DKFDHLVIET TGLADPAPVI QTFFVDEDLQ
SQLSLDAVVT VVDAKHISQH WDADEAQEQI AFADVILLNK TDLVAPEELN ELEKRIRAMN
AIAKIYRTQN SELGMDALLG VKAFDLDHAL EIDPDFLGED AHVHDESVFS VALVEAGAVD
GEKLNAWLSE LLRTQGPDIF RMKGILNIAG EDNRFVFQGV HMIFDGKPDR PWKASETPKN
ELVFIGRNLD AAQLKQDFLA CLA
//
