ID A0A1E2WTA7_9NOSO Unreviewed; 627 AA.
AC A0A1E2WTA7;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=protein-glutamate O-methyltransferase {ECO:0000256|ARBA:ARBA00012534};
DE EC=2.1.1.80 {ECO:0000256|ARBA:ARBA00012534};
GN ORFNames=A4S05_28205 {ECO:0000313|EMBL:ODH01610.1};
OS Nostoc sp. KVJ20.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Nostocaceae; Nostoc.
OX NCBI_TaxID=457944 {ECO:0000313|EMBL:ODH01610.1, ECO:0000313|Proteomes:UP000094607};
RN [1] {ECO:0000313|EMBL:ODH01610.1, ECO:0000313|Proteomes:UP000094607}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KVJ20 {ECO:0000313|EMBL:ODH01610.1,
RC ECO:0000313|Proteomes:UP000094607};
RA Wen L., He K., Yang H.;
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=L-glutamyl-[protein] + S-adenosyl-L-methionine = [protein]-L-
CC glutamate 5-O-methyl ester + S-adenosyl-L-homocysteine;
CC Xref=Rhea:RHEA:24452, Rhea:RHEA-COMP:10208, Rhea:RHEA-COMP:10311,
CC ChEBI:CHEBI:29973, ChEBI:CHEBI:57856, ChEBI:CHEBI:59789,
CC ChEBI:CHEBI:82795; EC=2.1.1.80;
CC Evidence={ECO:0000256|ARBA:ARBA00001541};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ODH01610.1}.
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DR EMBL; LSSA01000064; ODH01610.1; -; Genomic_DNA.
DR RefSeq; WP_069073093.1; NZ_KV757681.1.
DR AlphaFoldDB; A0A1E2WTA7; -.
DR OrthoDB; 9799157at2; -.
DR Proteomes; UP000094607; Unassembled WGS sequence.
DR GO; GO:0008757; F:S-adenosylmethionine-dependent methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd02440; AdoMet_MTases; 1.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 1.10.155.10; Chemotaxis receptor methyltransferase CheR, N-terminal domain; 1.
DR Gene3D; 1.10.287.620; Helix Hairpins; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR022642; CheR_C.
DR InterPro; IPR000780; CheR_MeTrfase.
DR InterPro; IPR022641; CheR_N.
DR InterPro; IPR036804; CheR_N_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR NCBIfam; TIGR00229; sensory_box; 2.
DR PANTHER; PTHR24422; CHEMOTAXIS PROTEIN METHYLTRANSFERASE; 1.
DR PANTHER; PTHR24422:SF25; CHEMOTAXIS PROTEIN METHYLTRANSFERASE; 1.
DR Pfam; PF01739; CheR; 1.
DR Pfam; PF03705; CheR_N; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF13596; PAS_10; 1.
DR PRINTS; PR00996; CHERMTFRASE.
DR SMART; SM00138; MeTrc; 1.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF47757; Chemotaxis receptor methyltransferase CheR, N-terminal domain; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS50123; CHER; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 1..250
FT /note="CheR-type methyltransferase"
FT /evidence="ECO:0000259|PROSITE:PS50123"
FT DOMAIN 500..570
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT REGION 424..455
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 627 AA; 72662 MW; D49D4BE5EC28882D CRC64;
MTSAERDPKF ENLLIYLRQS RGFDFTGYKR STLIRRVCKR MQSLTIENFE EYQDYLEVYP
DEFNYLFNTI LINVTAFFRD SSAWEYIAEQ ILPKLIKNKK TSDQIRIWSA GCASGEEAYT
LAMLMAEILG AEEFRQRVKI YATDVDEDAL NQARQAVYSA KDVQTIPDEL RQKYFEIAGN
RYVFRQDLRR SVIFGRHDLL QDAPISRLDL LVSRNTLMYF NSETQGRILA RFHFALNDNG
YLFLGKAEML LMHSALFTPL DLKNRIFTKV SAVNLRDRLL VMANSVDEES SSRLSRNLRL
REMGFDTAPI AQVIIDINGT LVMVNEQARV LFALSPKDLA RPFQDLELSY RPVELRSLIE
RAYTERRPVS LTNVERYLSN TETQYLDVRI TPLQETDNSF LGVSISFHDV TRYIQLQDAL
QRSQQELETT NEELQSTNEE LETTNEELQS TNEELETTNE ELQSTNEELE TMNEELQSTN
EELQTINNEL SERTTELNRT NIFLISILRS LQTGIVVIDS SFNISIWNYM VEDLWGLRND
EVIGKSIFSL DIGLPVEQLR SPIRDSLSGK KQFQEMILDA TNRRGRQIKC YLAITPLLGM
EMQGAVLMMA DVERVSSMIS SQEMEER
//
