ID   A0A1E3GS41_9GAMM        Unreviewed;       165 AA.
AC   A0A1E3GS41;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=Na(+)/H(+) antiporter subunit E {ECO:0000313|EMBL:ODN66870.1};
GN   Name=mrpE_2 {ECO:0000313|EMBL:ODN66870.1};
GN   ORFNames=A9E74_01420 {ECO:0000313|EMBL:ODN66870.1};
OS   Methylophaga muralis.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Thiotrichales;
OC   Piscirickettsiaceae; Methylophaga.
OX   NCBI_TaxID=291169 {ECO:0000313|EMBL:ODN66870.1, ECO:0000313|Proteomes:UP000094379};
RN   [1] {ECO:0000313|EMBL:ODN66870.1, ECO:0000313|Proteomes:UP000094379}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bur 1 {ECO:0000313|EMBL:ODN66870.1,
RC   ECO:0000313|Proteomes:UP000094379};
RA   Vasilenko O.V., Doronina N.V., Shmareva M.N., Tarlachkov S.V.,
RA   Mustakhimov I., Trotsenko Y.A.;
RT   "Draft Genome Sequence of Methylophaga muralis Bur 1.";
RL   Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E
CC       family. {ECO:0000256|ARBA:ARBA00006228}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ODN66870.1}.
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DR   EMBL; MCRI01000012; ODN66870.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1E3GS41; -.
DR   STRING; 291169.A9E74_01420; -.
DR   PATRIC; fig|291169.3.peg.1426; -.
DR   Proteomes; UP000094379; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR002758; Cation_antiport_E.
DR   PANTHER; PTHR34584; NA(+)/H(+) ANTIPORTER SUBUNIT E1; 1.
DR   PANTHER; PTHR34584:SF1; NA(+)_H(+) ANTIPORTER SUBUNIT E1; 1.
DR   Pfam; PF01899; MNHE; 1.
DR   PIRSF; PIRSF019239; MrpE; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000094379};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        63..85
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   165 AA;  19003 MW;  D63C3E0FA62C2062 CRC64;
     MMFRRIFPHP LLTLILWAIW LLLNNSIDPG HIVLGGALAV FIPWLTSSYW PEQINIRRPW
     KLVHYILYVL WDILIANVIV AKLILGPQKK LNPGFLHYEL QLTSPVGISL LANTISLTPG
     TVSCDLTEDR RYLLIHALHI DDVAEIKAEI YRKFEKPLLE IFVVC
//