ID A0A1E3GUU1_9GAMM Unreviewed; 774 AA.
AC A0A1E3GUU1;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=Aminomethyltransferase {ECO:0000313|EMBL:ODN67813.1};
DE EC=2.1.2.10 {ECO:0000313|EMBL:ODN67813.1};
GN Name=gcvT_1 {ECO:0000313|EMBL:ODN67813.1};
GN ORFNames=A9E74_00649 {ECO:0000313|EMBL:ODN67813.1};
OS Methylophaga muralis.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Thiotrichales;
OC Piscirickettsiaceae; Methylophaga.
OX NCBI_TaxID=291169 {ECO:0000313|EMBL:ODN67813.1, ECO:0000313|Proteomes:UP000094379};
RN [1] {ECO:0000313|EMBL:ODN67813.1, ECO:0000313|Proteomes:UP000094379}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bur 1 {ECO:0000313|EMBL:ODN67813.1,
RC ECO:0000313|Proteomes:UP000094379};
RA Vasilenko O.V., Doronina N.V., Shmareva M.N., Tarlachkov S.V.,
RA Mustakhimov I., Trotsenko Y.A.;
RT "Draft Genome Sequence of Methylophaga muralis Bur 1.";
RL Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ODN67813.1}.
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DR EMBL; MCRI01000003; ODN67813.1; -; Genomic_DNA.
DR RefSeq; WP_069295185.1; NZ_MCRI01000003.1.
DR AlphaFoldDB; A0A1E3GUU1; -.
DR STRING; 291169.A9E74_00649; -.
DR PATRIC; fig|291169.3.peg.651; -.
DR Proteomes; UP000094379; Unassembled WGS sequence.
DR GO; GO:0004047; F:aminomethyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR InterPro; IPR018959; DUF1989.
DR InterPro; IPR028896; GCST/YgfZ/DmdA.
DR InterPro; IPR013977; GCV_T_C.
DR InterPro; IPR006222; GCV_T_N.
DR InterPro; IPR029043; GcvT/YgfZ_C.
DR InterPro; IPR027266; TrmE/GcvT_dom1.
DR PANTHER; PTHR43757; AMINOMETHYLTRANSFERASE; 1.
DR PANTHER; PTHR43757:SF2; AMINOMETHYLTRANSFERASE, MITOCHONDRIAL; 1.
DR Pfam; PF09347; DUF1989; 1.
DR Pfam; PF01571; GCV_T; 1.
DR Pfam; PF08669; GCV_T_C; 1.
DR SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR SUPFAM; SSF103025; Folate-binding domain; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000313|EMBL:ODN67813.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000094379};
KW Transferase {ECO:0000313|EMBL:ODN67813.1}.
FT DOMAIN 178..346
FT /note="DUF1989"
FT /evidence="ECO:0000259|Pfam:PF09347"
FT DOMAIN 401..659
FT /note="Aminomethyltransferase folate-binding"
FT /evidence="ECO:0000259|Pfam:PF01571"
FT DOMAIN 686..766
FT /note="Glycine cleavage T-protein C-terminal barrel"
FT /evidence="ECO:0000259|Pfam:PF08669"
SQ SEQUENCE 774 AA; 85325 MW; E33F68553E102C88 CRC64;
MLEMKNQSWG EDYFFESSPS EPVRRFRLAG QQAIKLRLKA GDKLCIVSQD KVQNCELIVL
DSQGKSAPEL LDPRKPVAAL AIQQQLQQNG SAADKLRNQL ASWQLDATHL EQVLSVSGSE
AANFKAISDL TVVVAAAGAK MAVDEQNPVT EVDITITYAD QTECPLPEPL GPIKTELRIP
RASARTYEVK KGEWIQIIDV SGKQCSDFVA FDKQALDQGI EIPLDATSTR TVIGLSNPVP
GLHSRFLGTD LLSMVEVVQD TVGRHDSFLL ACTPKYYDDS GYFGHISCTE NFNRVLAPFG
IKPRAGWPAI NLFFNTAIDA SGAVFMDEPW SRAGDYVLFR ADRDLVCASS ACPDDIDPAN
GWHPTDIHVR IYGAEQQFPR AIAHRTTSEE LPRMTKASGF HSRTSELTKK FIDYAGYWVA
TEYNGWGANA EYLACRERVA VLDLSALRKF EVVGPDAVAF LQYVLTQNVS RMAIGEIAHS
AICLETGGMI DDGTIFRMGE QAYRWICGAE YTGVWMREKA QQKGFKVSIR NATEQLDNLA
VQGPKSRELL SEIVWTSDSQ PSVEKLKWFH FTIGRLGGPT GIPVMISRTG YTGELGYEVW
CHPDDSPTVW DAVWQAGQAY DIAPMGFDAL DILRIEAGLS MADHEFSHDI TPFEAGTGFS
VPLNSKQEDF IGRAALARQT PESRDKLVGM ILEGGDAAAH GDHVYNGRFP VGIVTSATYS
PLMGKQIAMV RIAPDFAHIG TRLEVGKLDG QQKRLAGQVV KLPFYDPKRE KLLS
//
