ID A0A1E3HIW4_9TREE Unreviewed; 784 AA.
AC A0A1E3HIW4;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=Ras-GAP domain-containing protein {ECO:0000259|PROSITE:PS50018};
GN ORFNames=L202_06212 {ECO:0000313|EMBL:ODN76283.1};
OS Cryptococcus amylolentus CBS 6039.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cryptococcaceae; Cryptococcus.
OX NCBI_TaxID=1295533 {ECO:0000313|EMBL:ODN76283.1, ECO:0000313|Proteomes:UP000094065};
RN [1] {ECO:0000313|EMBL:ODN76283.1, ECO:0000313|Proteomes:UP000094065}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 6039 {ECO:0000313|EMBL:ODN76283.1,
RC ECO:0000313|Proteomes:UP000094065};
RA Cuomo C., Litvintseva A., Heitman J., Chen Y., Sun S., Springer D.,
RA Dromer F., Young S., Zeng Q., Chapman S., Gujja S., Saif S., Birren B.;
RT "Evolution of pathogenesis and genome organization in the Tremellales.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ODN76283.1}.
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DR EMBL; AWGJ01000009; ODN76283.1; -; Genomic_DNA.
DR RefSeq; XP_018991814.1; XM_019140663.1.
DR AlphaFoldDB; A0A1E3HIW4; -.
DR STRING; 1295533.A0A1E3HIW4; -.
DR GeneID; 30157521; -.
DR OrthoDB; 24454at2759; -.
DR Proteomes; UP000094065; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProt.
DR CDD; cd05132; RasGAP_GAPA; 1.
DR InterPro; IPR000593; RasGAP_C.
DR InterPro; IPR023152; RasGAP_CS.
DR InterPro; IPR001936; RasGAP_dom.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR PANTHER; PTHR14149:SF17; GTPASE-ACTIVATING PROTEIN; 1.
DR PANTHER; PTHR14149; RAS GTPASE-ACTIVATING PROTEIN WITH IQ MOTIF; 1.
DR Pfam; PF00616; RasGAP; 1.
DR Pfam; PF03836; RasGAP_C; 1.
DR SMART; SM00323; RasGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF143885; RGC domain-like; 1.
DR PROSITE; PS00509; RAS_GTPASE_ACTIV_1; 1.
DR PROSITE; PS50018; RAS_GTPASE_ACTIV_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000094065}.
FT DOMAIN 178..394
FT /note="Ras-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50018"
FT REGION 1..31
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 52..79
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 784 AA; 89209 MW; F1A59925335FAE53 CRC64;
MTTMTMATPA TPSTSTHSPS ASVHSHLSRR LTNRMTNRYS VNAMYSLAAE QDIELEDELS
RAQKKLRDLK SRISSQSKKN FVLERDVRYL DSRIALLIQN RMAADEKRQV AETLEDVDED
SGLWPDEKKM GQYANLFFLL QSEPRHIASL CRLVSLSEID TLLQTVMFTL YGNQYEQREE
HLLLTMFQSV LSAQFETTTE FGSLLRANTP VSRMMTTYTR RGPGQSYLKG VLADRINSLI
EHKDLNLEIN PLKVYEQMIQ QIEEDTGSLP PSLPRGVPPE VAAANSDVQA IIIPRITMLM
EIANSFLSTI IDSLDSVPYG IRWICKQIRS LTRRKYPDAT DASICSLIGG FFFLRFINPA
IVTPQAYMLV DGVPAKHPRR TLTLIAKMLQ NLANKPSYAK EQYMMSLNPF VENNKTRMNQ
FLNALCEVGD FYESLELDQY MALSKKDLQI NITLNELYNT HSLLMQHMDV LSPNDKHHLR
ILLDELGAAP AQVPRKENRS IELPLYSRWE TPIQDLSTSL MSDSVTQNDI NYMETKSIFV
QLLRSMPTVA DKRPVNLGAL AEKAATSKDP VLVRRGIKVQ ALLAELDAAG VIDRADEYKL
MQDEVSAEMV HLGNAKEKVV LEARSLESVY KTICDHNNYL RGQLEQYKAY LQNVRLTSSK
DKGATGVGVV TVNGKEKKQV DKKVLGPYMF KHREFEKEGI IMESNVPENR RMNIYFMITS
PAPGTFIIAL HFKGRDKPIL EMDLKIDDLL EKQKDQQAML DLEYVQLNVP KVLALFNKLF
SKKR
//
