ID   A0A1E3HLV5_9TREE        Unreviewed;       567 AA.
AC   A0A1E3HLV5;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   13-SEP-2023, entry version 19.
DE   RecName: Full=Magnesium transporter NIPA-domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=L203_06277 {ECO:0000313|EMBL:ODN77337.1};
OS   Cryptococcus depauperatus CBS 7841.
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC   Tremellales; Cryptococcaceae; Cryptococcus.
OX   NCBI_TaxID=1295531 {ECO:0000313|EMBL:ODN77337.1, ECO:0000313|Proteomes:UP000094043};
RN   [1] {ECO:0000313|EMBL:ODN77337.1, ECO:0000313|Proteomes:UP000094043}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 7841 {ECO:0000313|EMBL:ODN77337.1,
RC   ECO:0000313|Proteomes:UP000094043};
RA   Cuomo C., Litvintseva A., Heitman J., Chen Y., Sun S., Springer D.,
RA   Dromer F., Young S., Zeng Q., Chapman S., Gujja S., Saif S., Birren B.;
RT   "Evolution of pathogenesis and genome organization in the Tremellales.";
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ODN77337.1}.
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DR   EMBL; AWGK01000035; ODN77337.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1E3HLV5; -.
DR   VEuPathDB; FungiDB:L203_06277; -.
DR   OrthoDB; 1367316at2759; -.
DR   Proteomes; UP000094043; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 1.10.3730.20; -; 1.
DR   InterPro; IPR008521; Mg_trans_NIPA.
DR   PANTHER; PTHR12570:SF82; EXPRESSED PROTEIN; 1.
DR   PANTHER; PTHR12570; UNCHARACTERIZED; 1.
DR   Pfam; PF05653; Mg_trans_NIPA; 1.
DR   SUPFAM; SSF103481; Multidrug resistance efflux transporter EmrE; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000094043};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        72..96
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        116..135
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        147..167
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        179..197
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        217..242
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        311..334
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        340..361
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        373..395
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        401..425
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          455..567
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        467..486
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        493..507
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        519..548
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   567 AA;  61158 MW;  3E6F47B82590B5D0 CRC64;
     MENVQNSSSA YNDIIAATST SSLVSAITSS LISVTSGSSF SFEGLGSIDN NSAVFDGGGM
     ATPDAELDDG NYILNTLVGL LIVLTASVFN ALGLNLTKLD HVQQQAIPKR QRKKEYMRLL
     WLSGMGMYIA SQVLGSPLAL KYLRPDWVAP LGSSSLVFNF MFAYWLVGTP VTTTDIRGTA
     IIILGVILII VFSSINHGLI QGLSIHRLNG LWSRPAWIAY LILIVAFTSV TYLTSSFLGA
     LVSSRASFSP LPSPSLELPA SRPSSPGKVV SVYRTIRSIW ARFRKLALDR MEILFSRTGD
     ERLTWLQGIG WAVAGGSLAG LCLVFTKAVV KIFWLPGHPL VHPSALISLL SVIITAILQI
     ICLNKALVCA DTVVVVPLFY AGYTVLGFIN SLIFYDEVGQ YARWVLIAVF LSIAILISGV
     VLLSLKSSTK TAADPYTIST EPSSINMRLR PTQTKTKLGQ DAEAGQADSL GNDNRTGLST
     SRENVLWEVG SVGDDSDTEH EAEGKGKGVG GIRGGSGERR GLLGEEERDI HEEDDGHAMS
     RPESATQDDD FGEYEDVTTD DPEKHSK
//