ID A0A1E3HQ48_9TREE Unreviewed; 581 AA.
AC A0A1E3HQ48;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=CobW C-terminal domain-containing protein {ECO:0000259|SMART:SM00833};
GN ORFNames=L202_04104 {ECO:0000313|EMBL:ODN78468.1};
OS Cryptococcus amylolentus CBS 6039.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cryptococcaceae; Cryptococcus.
OX NCBI_TaxID=1295533 {ECO:0000313|EMBL:ODN78468.1, ECO:0000313|Proteomes:UP000094065};
RN [1] {ECO:0000313|EMBL:ODN78468.1, ECO:0000313|Proteomes:UP000094065}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 6039 {ECO:0000313|EMBL:ODN78468.1,
RC ECO:0000313|Proteomes:UP000094065};
RA Cuomo C., Litvintseva A., Heitman J., Chen Y., Sun S., Springer D.,
RA Dromer F., Young S., Zeng Q., Chapman S., Gujja S., Saif S., Birren B.;
RT "Evolution of pathogenesis and genome organization in the Tremellales.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. ZNG1
CC subfamily. {ECO:0000256|ARBA:ARBA00034320}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ODN78468.1}.
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DR EMBL; AWGJ01000006; ODN78468.1; -; Genomic_DNA.
DR RefSeq; XP_018993514.1; XM_019138078.1.
DR AlphaFoldDB; A0A1E3HQ48; -.
DR STRING; 1295533.A0A1E3HQ48; -.
DR GeneID; 30155413; -.
DR OrthoDB; 50694at2759; -.
DR Proteomes; UP000094065; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd03112; CobW-like; 1.
DR Gene3D; 3.30.1220.10; CobW-like, C-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR036627; CobW-likC_sf.
DR InterPro; IPR011629; CobW-like_C.
DR InterPro; IPR003495; CobW/HypB/UreG_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR43603; COBW DOMAIN-CONTAINING PROTEIN DDB_G0274527; 1.
DR PANTHER; PTHR43603:SF1; COBW DOMAIN-CONTAINING PROTEIN DDB_G0274527; 1.
DR Pfam; PF02492; cobW; 2.
DR Pfam; PF07683; CobW_C; 1.
DR SMART; SM00833; CobW_C; 1.
DR SUPFAM; SSF90002; Hypothetical protein YjiA, C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000094065};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..581
FT /note="CobW C-terminal domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5009129287"
FT DOMAIN 334..512
FT /note="CobW C-terminal"
FT /evidence="ECO:0000259|SMART:SM00833"
FT REGION 364..394
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 557..581
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 365..384
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 581 AA; 64581 MW; 480B7C52BBD16355 CRC64;
MRVVSFLISI SCLIQPPRAP VANMPVATDA DTRLPVTLLS GFLGSGKTTL LSYILKSKDH
GLRCAVVVND MGSLNIDAAL ISNHKLTQKE EKVVQMQNGC ICCTLRADLL EEIAALADAG
HYDYLIIESS GISEPIQVAE TFTSEFANTM GGGTLDEIIE SLPEDASATP ESRKKLAELI
HQGGLSKVAR LDCCVSMVDC TTFLDDFDTT DFLTDRHGKE VDPEDEKNIT DLLTDQIEFA
NVILLNKTDI IHKSQVAQIE QIVKTLNPGA KIIPTSYSKV DLHEILNTRL FDFGKAAMGA
GWLQSLRENT LMEITDQHGN TKMVPKPETL EYGIGSFVYT ARRPFHPHRL WDLVSEPFCV
LQTTVEDDDS DDSDDDDEST PDELSEEEAK QANFDAMQKE KAELDLPGRA RAKRASPVWK
GLLRSKGFVW LATRPGVHGE WSQAGIMFTL NGGGPWMCRV PESEWPGSDD QEVIDAIKLD
FMGPWGDRRQ ELVFIGQNLD QELISKTLDE ALLDDKEWAK WEKIMKSRCS DDKKTGRLLD
EFDDGWEAWL DPGMMEEGTH DAHAGHHHDH TPLAKKAKLS G
//
