ID   A0A1E3HT34_9TREE        Unreviewed;       377 AA.
AC   A0A1E3HT34;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   SubName: Full=Isocitrate dehydrogenase, NAD-dependent {ECO:0000313|EMBL:ODN79504.1};
GN   ORFNames=L202_03472 {ECO:0000313|EMBL:ODN79504.1};
OS   Cryptococcus amylolentus CBS 6039.
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC   Tremellales; Cryptococcaceae; Cryptococcus.
OX   NCBI_TaxID=1295533 {ECO:0000313|EMBL:ODN79504.1, ECO:0000313|Proteomes:UP000094065};
RN   [1] {ECO:0000313|EMBL:ODN79504.1, ECO:0000313|Proteomes:UP000094065}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 6039 {ECO:0000313|EMBL:ODN79504.1,
RC   ECO:0000313|Proteomes:UP000094065};
RA   Cuomo C., Litvintseva A., Heitman J., Chen Y., Sun S., Springer D.,
RA   Dromer F., Young S., Zeng Q., Chapman S., Gujja S., Saif S., Birren B.;
RT   "Evolution of pathogenesis and genome organization in the Tremellales.";
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the isocitrate and isopropylmalate
CC       dehydrogenases family. {ECO:0000256|ARBA:ARBA00007769}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ODN79504.1}.
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DR   EMBL; AWGJ01000005; ODN79504.1; -; Genomic_DNA.
DR   RefSeq; XP_018994351.1; XM_019137325.1.
DR   AlphaFoldDB; A0A1E3HT34; -.
DR   STRING; 1295533.A0A1E3HT34; -.
DR   GeneID; 30154781; -.
DR   OrthoDB; 143577at2759; -.
DR   Proteomes; UP000094065; Unassembled WGS sequence.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR   Gene3D; 3.40.718.10; Isopropylmalate Dehydrogenase; 1.
DR   InterPro; IPR004434; Isocitrate_DH_NAD.
DR   InterPro; IPR024084; IsoPropMal-DH-like_dom.
DR   NCBIfam; TIGR00175; mito_nad_idh; 1.
DR   PANTHER; PTHR11835; DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE; 1.
DR   PANTHER; PTHR11835:SF42; ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT GAMMA, MITOCHONDRIAL; 1.
DR   Pfam; PF00180; Iso_dh; 1.
DR   SMART; SM01329; Iso_dh; 1.
DR   SUPFAM; SSF53659; Isocitrate/Isopropylmalate dehydrogenase-like; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000094065};
KW   Transit peptide {ECO:0000256|ARBA:ARBA00022946}.
FT   DOMAIN          45..372
FT                   /note="Isopropylmalate dehydrogenase-like"
FT                   /evidence="ECO:0000259|SMART:SM01329"
SQ   SEQUENCE   377 AA;  40976 MW;  4AD337AE7BF397BF CRC64;
     MLAHSLRSSA TTAIRANAAR VPAVRSMATL VDEKRLPSKF GGKYTVTLVP GDGIGREVAD
     SVKEIFEAIK APVQWEQYDV SGETTGGEAL FQEAMDSLKR NKVGLKGILY TPIDQTGHNS
     WNVAMRQQLD IYASVVVCKS LPGFPTRHAD VDLALIRENT EGEYSGLEHQ SFPGVVESLK
     VSTRAKAERI ARFAFDFAIK NNRKKVTCVH KANIMKLGDG LFLNTCKRIA EQEYGHTGIK
     FESMIVDNTA MQLVSRPQQF DVMVMPNLYG AICSNIASAL VGGPGITPGC NFGREYALFE
     PGCRHVGKDI MGANKANPVA LILSATMMLR HLGLETQANL IAGATYDLVR EGKVRTADLG
     GNASTTDVTK DIINRIL
//