ID A0A1E3I2J8_9TREE Unreviewed; 563 AA.
AC A0A1E3I2J8;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=Uracil permease {ECO:0008006|Google:ProtNLM};
GN ORFNames=L202_02468 {ECO:0000313|EMBL:ODN82176.1};
OS Cryptococcus amylolentus CBS 6039.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cryptococcaceae; Cryptococcus.
OX NCBI_TaxID=1295533 {ECO:0000313|EMBL:ODN82176.1, ECO:0000313|Proteomes:UP000094065};
RN [1] {ECO:0000313|EMBL:ODN82176.1, ECO:0000313|Proteomes:UP000094065}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 6039 {ECO:0000313|EMBL:ODN82176.1,
RC ECO:0000313|Proteomes:UP000094065};
RA Cuomo C., Litvintseva A., Heitman J., Chen Y., Sun S., Springer D.,
RA Dromer F., Young S., Zeng Q., Chapman S., Gujja S., Saif S., Birren B.;
RT "Evolution of pathogenesis and genome organization in the Tremellales.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the purine-cytosine permease (2.A.39) family.
CC {ECO:0000256|ARBA:ARBA00008974}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ODN82176.1}.
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DR EMBL; AWGJ01000003; ODN82176.1; -; Genomic_DNA.
DR RefSeq; XP_018996495.1; XM_019136092.1.
DR AlphaFoldDB; A0A1E3I2J8; -.
DR GeneID; 30153777; -.
DR OrthoDB; 1218881at2759; -.
DR Proteomes; UP000094065; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd11482; SLC-NCS1sbd_NRT1-like; 1.
DR Gene3D; 1.10.4160.10; Hydantoin permease; 1.
DR InterPro; IPR012681; NCS1.
DR InterPro; IPR001248; Pur-cyt_permease.
DR InterPro; IPR045225; Uracil/uridine/allantoin_perm.
DR NCBIfam; TIGR00800; ncs1; 1.
DR PANTHER; PTHR30618:SF2; ALLANTOIN PERMEASE-RELATED; 1.
DR PANTHER; PTHR30618; NCS1 FAMILY PURINE/PYRIMIDINE TRANSPORTER; 1.
DR Pfam; PF02133; Transp_cyt_pur; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000094065};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 74..94
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 173..192
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 199..218
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 238..258
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 279..301
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 328..348
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 369..387
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 399..418
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 448..467
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 479..502
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 532..563
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 532..557
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 563 AA; 62197 MW; 6A8A13F64FDE18F0 CRC64;
MPLRAGTLLK KLESNHAEGL SRKEMFLATE DLLPVTEDKK TWDSWNFAMF WVADSFNLNT
FTIASSMMSS GLNWWQSLVC VIVGYSLVGP LLVLNARPGA MHGIVFPAAC RTTFGVFGSL
WPVFNRAAMA CIWWGVQSWL GGECMYVLVR AIWPSFARIH NSMPESTETT TAYIVAFILY
WILSLPTIWV PIHKLRWLFL GKAIVGPIVG FTLFGWSITR AGGIGPVFSQ KATLSGSALG
WQMIISISSC FNNMFTLVTN SCDFASRAKK PSAAVWPQII AMPIGFSITS FLGIVIASAS
APQFGEQIWD VVKIMDAMLD DGSSATRAGL VFIAAGFVYV QLLLNVAANS ISAGCDLTAL
FPRYLSIRRG GYVAAIVGIC MNPWLLYKSS ATFSNYLGAY GVLLSCIAGP MVTDYWLVRR
GHIRVNDLYS GEEDGWYWYS MGVNWRGYLA YFVGFAFNAP GFINALRPDI IVPVGFQRVY
YLSWLTGTGI SGAVYFLACY FFPPPGMNMH FEEVDESAGE LRVDQKLEGK MRGEGEWEEG
GVERFEGAEK KKSQDGNVTV LEA
//
