ID   A0A1E3IEW8_9TREE        Unreviewed;       673 AA.
AC   A0A1E3IEW8;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Nuclear protein {ECO:0000313|EMBL:ODN87058.1};
GN   ORFNames=L203_03832 {ECO:0000313|EMBL:ODN87058.1};
OS   Cryptococcus depauperatus CBS 7841.
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC   Tremellales; Cryptococcaceae; Cryptococcus.
OX   NCBI_TaxID=1295531 {ECO:0000313|EMBL:ODN87058.1, ECO:0000313|Proteomes:UP000094043};
RN   [1] {ECO:0000313|EMBL:ODN87058.1, ECO:0000313|Proteomes:UP000094043}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 7841 {ECO:0000313|EMBL:ODN87058.1,
RC   ECO:0000313|Proteomes:UP000094043};
RA   Cuomo C., Litvintseva A., Heitman J., Chen Y., Sun S., Springer D.,
RA   Dromer F., Young S., Zeng Q., Chapman S., Gujja S., Saif S., Birren B.;
RT   "Evolution of pathogenesis and genome organization in the Tremellales.";
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=L-ascorbate; Xref=ChEBI:CHEBI:38290;
CC         Evidence={ECO:0000256|ARBA:ARBA00001961};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ODN87058.1}.
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DR   EMBL; AWGK01000015; ODN87058.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1E3IEW8; -.
DR   STRING; 1295531.A0A1E3IEW8; -.
DR   VEuPathDB; FungiDB:L203_03832; -.
DR   OrthoDB; 100633at2759; -.
DR   Proteomes; UP000094043; Unassembled WGS sequence.
DR   GO; GO:0016706; F:2-oxoglutarate-dependent dioxygenase activity; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0031418; F:L-ascorbic acid binding; IEA:UniProtKB-KW.
DR   GO; GO:0071704; P:organic substance metabolic process; IEA:UniProt.
DR   Gene3D; 3.60.130.20; Oxoglutarate/iron-dependent oxygenase, C-terminal degradation domain; 1.
DR   Gene3D; 2.60.120.620; q2cbj1_9rhob like domain; 1.
DR   InterPro; IPR019601; Oxoglutarate/Fe-dep_Oase_C.
DR   InterPro; IPR006620; Pro_4_hyd_alph.
DR   InterPro; IPR043044; TPA1/Ofd1_C.
DR   InterPro; IPR039558; TPA1/OFD1_N.
DR   PANTHER; PTHR12117; HISTONE ACETYLTRANSFERASE COMPLEX; 1.
DR   PANTHER; PTHR12117:SF0; PROLYL 3-HYDROXYLASE OGFOD1; 1.
DR   Pfam; PF13661; 2OG-FeII_Oxy_4; 1.
DR   Pfam; PF10637; Ofd1_CTDD; 1.
DR   SMART; SM00702; P4Hc; 1.
PE   4: Predicted;
KW   Dioxygenase {ECO:0000256|ARBA:ARBA00022964};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000094043};
KW   Vitamin C {ECO:0000256|ARBA:ARBA00022896}.
FT   DOMAIN          54..284
FT                   /note="Prolyl 4-hydroxylase alpha subunit"
FT                   /evidence="ECO:0000259|SMART:SM00702"
FT   REGION          1..37
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          523..611
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        539..566
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        567..597
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   673 AA;  73624 MW;  65A901DAD280280D CRC64;
     MPAAARERSP SSAAGRSAKK HKNSPDQSAT ASINHPSVDQ VTAYREEYVN ASPFKHAVIS
     GVLSDEMLEG VVQECKKFGI RGEEGSLPGW GWEQKETDIY KIQQTPDLSS LSPEHLPDVT
     LEALPQLTRL KEALYSQEFR NLVRQVTGCG ALSGKKTDLS AALYTKGSHL LLHDDSISSR
     LVSYILYLPY SSADAAKGDV ELVPSANGDF FKGWDPAWGG SLELFPVETG EEVGPPSVKR
     HKKVSATWGQ IIIFEVQPGR SYHAVEEVVV DEGRRRFSVS GWFHRPVEDE EGYQVFDQEK
     AKKDLSSLAQ ITAAPSISFL SYPTPPPPGL KPSDIAFLAN YLASSYLTST TLERLSGQFV
     EASEIVLHNF LLPELAAKLK AETESADKKD YGSYKGLLTP QDLGEDDGWV IQGPSSKHRY
     LSLTSLSTST PIIQSIHNVL FPSDAFRAWL SVVSSLAPVG HRNEARRFRK GLDYTLANGE
     GKDGDARLDV SLGATWWADV PAGSDEEDTL AEHGGWEAYL AAPDEDEDPA VYQSSLAKKA
     AKADRDHDAH HANGNKERKV ETSEHKANGN GTDGPSISTG NQELEFDPNQ FSPSDFDSDS
     EANEEDDGPL LTQPVAFNKL LLVLRDPGVM KFVKYLGASA PGSRWDVQGE YEVGVLEEEE
     EEEREEGSGE VRT
//