ID A0A1E3ITC0_9TREE Unreviewed; 2506 AA.
AC A0A1E3ITC0;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 08-NOV-2023, entry version 30.
DE RecName: Full=Beige/BEACH domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=L203_01081 {ECO:0000313|EMBL:ODN91829.1};
OS Cryptococcus depauperatus CBS 7841.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cryptococcaceae; Cryptococcus.
OX NCBI_TaxID=1295531 {ECO:0000313|EMBL:ODN91829.1, ECO:0000313|Proteomes:UP000094043};
RN [1] {ECO:0000313|EMBL:ODN91829.1, ECO:0000313|Proteomes:UP000094043}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 7841 {ECO:0000313|EMBL:ODN91829.1,
RC ECO:0000313|Proteomes:UP000094043};
RA Cuomo C., Litvintseva A., Heitman J., Chen Y., Sun S., Springer D.,
RA Dromer F., Young S., Zeng Q., Chapman S., Gujja S., Saif S., Birren B.;
RT "Evolution of pathogenesis and genome organization in the Tremellales.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ODN91829.1}.
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DR EMBL; AWGK01000004; ODN91829.1; -; Genomic_DNA.
DR STRING; 1295531.A0A1E3ITC0; -.
DR VEuPathDB; FungiDB:L203_01081; -.
DR OrthoDB; 5478899at2759; -.
DR Proteomes; UP000094043; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR CDD; cd06071; Beach; 1.
DR CDD; cd01201; PH_BEACH; 1.
DR Gene3D; 1.10.1540.10; BEACH domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR000409; BEACH_dom.
DR InterPro; IPR036372; BEACH_dom_sf.
DR InterPro; IPR023362; PH-BEACH_dom.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR InterPro; IPR000306; Znf_FYVE.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR46108; BLUE CHEESE; 1.
DR PANTHER; PTHR46108:SF4; BLUE CHEESE; 1.
DR Pfam; PF02138; Beach; 1.
DR Pfam; PF14844; PH_BEACH; 1.
DR SMART; SM01026; Beach; 1.
DR SMART; SM00064; FYVE; 1.
DR SMART; SM00320; WD40; 1.
DR SUPFAM; SSF81837; BEACH domain; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50197; BEACH; 1.
DR PROSITE; PS51783; PH_BEACH; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 1.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000094043};
KW WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT DOMAIN 1612..1736
FT /note="BEACH-type PH"
FT /evidence="ECO:0000259|PROSITE:PS51783"
FT DOMAIN 1761..2049
FT /note="BEACH"
FT /evidence="ECO:0000259|PROSITE:PS50197"
FT REPEAT 2187..2228
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 1..74
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 431..458
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1325..1367
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2476..2506
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 29..63
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 432..458
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2506 AA; 280270 MW; A7BE8E4A35326197 CRC64;
MFKLIKDLTR PPESLTPPVI PVASSPTPYA VRHKTQSRSR SGSATNRDPN ETLPLSSQRA
KSPRAFASGR EAVGATGDAE DSAWSFALDF DIDEDEVEQS AKRVVEIIRD LRSGGTLDVM
RYVEGFSQLL TIPGDYYSLR AWRRHNGIQI LLLALSKGLC WKPRGENMGE EQYQVLEVQR
MEGIRLAFEV LGWALGDRLG EAYFKQQGGY RLFLPILYPL APPTTPPNSP DRQILAHLFA
HICSNSYAFL TLFQSPPLSL SDISSRLGDV LVRPSTSDAL GLIWLYLLGE SLQAKDEEKV
WMNAVEGEEG SERNKLFQLT FQLFLVIGQA SSLNLFILVS QLHDLANFLV TKLYGPKEKR
EYEITFLSRD DWLVEREEEE EKKEELVWRQ PTNRLRSTYL LLLKKILEAG VDHKTTWRLF
ELVKIQGKKI STPPTEVDSN NSSSEKTTAS PDSIGSPTSS AVFVPKNSTF RGKPNLYINT
IKTGEDDEER LQPEVLDLIR HALKSKWPDV FVFNGGSADS LGGLNLRETG RDWMNAHKGL
NFSCWIHITK LNQPLTLLHV SQKSSKDPLF QVRILESSQI AITTSVHSDS SSSAEPSSIN
EVVCSAPGAL IPHFQWVHFA VGCHKLRGHE SGEVKIFLNG SRVGVMRMPF PVPKCPSAPL
PILPPGVQRD EGSSRATRIA IGKEYRGDEE ESVRATERLG KEEENQWMLG RALLLEEAIP
EDLVLLLHHL GPRYTGNLQE PLGKFLTYEG ATSINIYLHG LAQLSKDKKL FTQQHSSSIL
VRAIRSGYVI PEESIVLSIS AKDYDPLQDI CINSSIPHPY RAKQFKCGIV KLTGNVRPFK
TIGLDESVQA VGGGLVLLNI VSMSQTREEL FSALSILKDA IRDNWSASEE MERIQGFDLL
AAILRPKAAK LLDETCTKVV LAMLGINMDK PNTATVHNSV AYRSIGLEFE LWSYASDKVI
RYYLQHFEYL LSISKHKRFN NLRTFQKLAT VRKMLYALRS GLFNSDVMPD VVDTLGKVLE
VRWSSQDGIK PIFSYLVSAL CQNNTTVSST ISGEPPTYQL PAVLILRKIS QLCHSSSRLV
KLIRSIALHR LLIIFLSSNS SYYVVLPCLN LLEHCFNTSG LEHFQKSFES EGGFALLARI
LPPIWNSDIQ NMSIRILLGN DPMKKLHSSS MMATLLAALE LLLQTAGNSE ENRRPSTRAA
MLGAVTSVKY VTTISSPIDS KHTWAPHTRL ESLLTELDRL YRCYPAARKQ INHKKIEAML
PHFADFAAIS SNIKSDIIKD QREAAACWLS SLLVHGQLPQ STVTQIELLI EQLCTLPISP
RNSSSLTISN SSPQSSSHFS QSFSSRLGTS TGVPSSSRRR SSVDAGMIST PAFTRSRSII
ERKSPLKRTI TGESILEGGK DKNSAWKMII IQTVSENTGL TKQPWNRKEH WLKLSQFDWP
QQAAVLRSEN GLWPRKDERI TWRLDGSEGP LRMRQAALLR QLESRLIHCR ARLERIDDVP
EQGLTRKRHK MRDAIPSADE LSSAISQINT SPWEDPFALA LGDTAPIPEE GFAILTAPDD
ENLNVIPSKS KASFAVLQTG EIASEENVDS DSLFEIDDGD NNRMKKIAKS LQPGDAVEEA
HNIVRIVGVD ACPGLLILGR KNLYLVDGLV QRSDGAIIDA KDAEKDVLSI PSGTLAELSA
DNQQSHCWQY NEIIENNRRA FLFRDVALEL YFSDKRNFLI VFRDKRERQA VVQSIHSKND
HRDPISKSII GNFVLDTVAR AMDRSEQQLE AWQRKWQNRE ITNFAYLQLL NQYANRTPND
VTQYPVFPWV LADYTSDRLD LTSESSFRDL NFPMGAITEA RREAATERYA ATESVGEKPF
HYGTHYSSSM IVCGYLIRLS PFTEIFLALQ GGNFDLADRL FSSIPKAWSS ASSDNRGDVR
ELIPEFFYSP AFLYNLAGFR ILKQASGDTV DNVTLPPWAL EDPHLFIHRH REALESEHVS
RHLPSWIDLT FGYKQRDPAS FNCFHPLSYR GTIDLENIED EGEKAASTAI IHNFGQTPLQ
IFKSPHPRRY MTGRSDLPIG VKFGVAEHWQ LMFRSILPIT ESSNPIDGIN LHSSLDTKPR
ISQKHRLLVP GSSHLSIQYG FTDGSIRVYY QETLVLIIEG IYPEHAIFAA PSLFVTVSQG
VIMAWRLTIR GTGHRRGDVT MQREASLRGH THRVTCLCAN TSWSLLVSGS EGGKAMVWDT
NRLRYIRTLQ TGRDEQIHFC TINEADGQIA LASKRHLYLF TLNGHPLAST SSAVCTPLIH
GDAVLSDSEE IFDDDFTGGI SYLTREFLKD GTLFVIGVGK QVILYRCAPG TNEGLDGSQD
VAPWELVALG MMHRSNHHGS GDCCMVKFVG ETLYAAFQPL NRRLKYTLYQ WSLPDGPARH
VAESVSNTCM AGGCTRHFGL LEPKRHCGGC GGAFCGTHAL HVEAFAMRYC DACRAQLSIA
SAQGLLDSRR NAFTVPSNPV SRRGSISHDN LSSHISVAKS QNQPRS
//
