ID A0A1E3NEQ8_9ASCO Unreviewed; 606 AA.
AC A0A1E3NEQ8;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=ABC transporter domain-containing protein {ECO:0000259|PROSITE:PS50893};
GN ORFNames=PICMEDRAFT_74993 {ECO:0000313|EMBL:ODQ44048.1};
OS Pichia membranifaciens NRRL Y-2026.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Pichiaceae; Pichia.
OX NCBI_TaxID=763406 {ECO:0000313|EMBL:ODQ44048.1, ECO:0000313|Proteomes:UP000094455};
RN [1] {ECO:0000313|EMBL:ODQ44048.1, ECO:0000313|Proteomes:UP000094455}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL Y-2026 {ECO:0000313|EMBL:ODQ44048.1,
RC ECO:0000313|Proteomes:UP000094455};
RX PubMed=27535936; DOI=10.1073/pnas.1603941113;
RA Riley R., Haridas S., Wolfe K.H., Lopes M.R., Hittinger C.T., Goeker M.,
RA Salamov A.A., Wisecaver J.H., Long T.M., Calvey C.H., Aerts A.L.,
RA Barry K.W., Choi C., Clum A., Coughlan A.Y., Deshpande S., Douglass A.P.,
RA Hanson S.J., Klenk H.-P., LaButti K.M., Lapidus A., Lindquist E.A.,
RA Lipzen A.M., Meier-Kolthoff J.P., Ohm R.A., Otillar R.P., Pangilinan J.L.,
RA Peng Y., Rokas A., Rosa C.A., Scheuner C., Sibirny A.A., Slot J.C.,
RA Stielow J.B., Sun H., Kurtzman C.P., Blackwell M., Grigoriev I.V.,
RA Jeffries T.W.;
RT "Comparative genomics of biotechnologically important yeasts.";
RL Proc. Natl. Acad. Sci. U.S.A. 113:9882-9887(2016).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; KV454010; ODQ44048.1; -; Genomic_DNA.
DR RefSeq; XP_019015161.1; XM_019164933.1.
DR AlphaFoldDB; A0A1E3NEQ8; -.
DR STRING; 763406.A0A1E3NEQ8; -.
DR GeneID; 30181620; -.
DR OrthoDB; 1709033at2759; -.
DR Proteomes; UP000094455; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03233; ABCG_PDR_domain1; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR029481; ABC_trans_N.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR034001; ABCG_PDR_1.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR19241:SF620; ABC TRANSPORTER ATP-BINDING PROTEIN_PERMEASE PDR18-RELATED; 1.
DR PANTHER; PTHR19241; ATP-BINDING CASSETTE TRANSPORTER; 1.
DR Pfam; PF01061; ABC2_membrane; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR Pfam; PF14510; ABC_trans_N; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000094455};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 268..292
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 517..541
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 553..574
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 132..409
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT REGION 1..38
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..18
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 19..38
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 606 AA; 68899 MW; A435488DC2B70B93 CRC64;
MEKPAENHSN DTDSIDSDNQ DVQKFNPLND PEDQGNAENL SHHVSRILST QEGMERVATL
ARVLSTKTKK DMDHFEINKE NFDLELLLKY LRDRSAEQGI ESANAGVSFR DLTCWGVDAS
AAHGPSVTEM SINYLSFWKM FQKDNRKQRM IIQNFVGVLE PGEMVLCLGK PGAGCSSLLK
AVAGEIENFT KVEGSFSYDG LDQAEMMQKY KGYVVYNPEL DFHFPYITVK ETIQLALRCK
TPQKRIDNMS RSEYVDNMLR VSFLQTTFFF SHSILTFVFD FLLQLWCTVF GLTHTYATRV
GNDFVRGVSG GERKRVSIVE ALALNASVYC FDNATRGLDA STALEFTQCL RTATNMLGCS
AFVAIYQAGQ NIYELFDKVS VLYKGRQIYW GPADQGVSYF EKMGYLKPSR MTAPEFLTAV
TSPSSRQVQP GFEGKVPESS EEFAEYWVNS PEYANLMTEM DEFDANHNGD ETRQRLDFVN
QQRKQKGNRQ KSQFMVTYWS QLYYLMLRGF QRTKGNITYT IVYISSFVTK GFVVGSMYYH
IPKSTNGAYS RGGILFYVLL FCSVTSLAEI ANSFSTRNIL VKQKSYSMYH LSAEALQEII
TEFPRS
//
