ID A0A1E3NQP4_9ASCO Unreviewed; 926 AA.
AC A0A1E3NQP4;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=LIM zinc-binding domain-containing protein {ECO:0000259|PROSITE:PS50023};
GN ORFNames=PICMEDRAFT_10946 {ECO:0000313|EMBL:ODQ48018.1};
OS Pichia membranifaciens NRRL Y-2026.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Pichiaceae; Pichia.
OX NCBI_TaxID=763406 {ECO:0000313|EMBL:ODQ48018.1, ECO:0000313|Proteomes:UP000094455};
RN [1] {ECO:0000313|EMBL:ODQ48018.1, ECO:0000313|Proteomes:UP000094455}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL Y-2026 {ECO:0000313|EMBL:ODQ48018.1,
RC ECO:0000313|Proteomes:UP000094455};
RX PubMed=27535936; DOI=10.1073/pnas.1603941113;
RA Riley R., Haridas S., Wolfe K.H., Lopes M.R., Hittinger C.T., Goeker M.,
RA Salamov A.A., Wisecaver J.H., Long T.M., Calvey C.H., Aerts A.L.,
RA Barry K.W., Choi C., Clum A., Coughlan A.Y., Deshpande S., Douglass A.P.,
RA Hanson S.J., Klenk H.-P., LaButti K.M., Lapidus A., Lindquist E.A.,
RA Lipzen A.M., Meier-Kolthoff J.P., Ohm R.A., Otillar R.P., Pangilinan J.L.,
RA Peng Y., Rokas A., Rosa C.A., Scheuner C., Sibirny A.A., Slot J.C.,
RA Stielow J.B., Sun H., Kurtzman C.P., Blackwell M., Grigoriev I.V.,
RA Jeffries T.W.;
RT "Comparative genomics of biotechnologically important yeasts.";
RL Proc. Natl. Acad. Sci. U.S.A. 113:9882-9887(2016).
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DR EMBL; KV454002; ODQ48018.1; -; Genomic_DNA.
DR RefSeq; XP_019019131.1; XM_019159734.1.
DR AlphaFoldDB; A0A1E3NQP4; -.
DR STRING; 763406.A0A1E3NQP4; -.
DR GeneID; 30176421; -.
DR OrthoDB; 1422336at2759; -.
DR Proteomes; UP000094455; Unassembled WGS sequence.
DR GO; GO:0030695; F:GTPase regulator activity; IEA:UniProt.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd08368; LIM; 1.
DR CDD; cd09397; LIM1_UF1; 1.
DR Gene3D; 2.10.110.10; Cysteine Rich Protein; 2.
DR InterPro; IPR001781; Znf_LIM.
DR PANTHER; PTHR24205; FOUR AND A HALF LIM DOMAINS PROTEIN; 1.
DR PANTHER; PTHR24205:SF4; LIM DOMAIN FAMILY; 1.
DR Pfam; PF00412; LIM; 2.
DR SMART; SM00132; LIM; 2.
DR SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 1.
DR PROSITE; PS00478; LIM_DOMAIN_1; 2.
DR PROSITE; PS50023; LIM_DOMAIN_2; 1.
PE 4: Predicted;
KW LIM domain {ECO:0000256|PROSITE-ProRule:PRU00125};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00125};
KW Reference proteome {ECO:0000313|Proteomes:UP000094455};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00125}.
FT DOMAIN 775..841
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 59..194
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 211..257
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 312..335
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 382..410
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 612..633
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 647..678
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 691..746
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 88..135
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 149..194
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 211..233
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 382..407
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 691..715
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 722..746
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 926 AA; 103203 MW; C11B3B7274D8B938 CRC64;
MSSSSNFFKP AATPLDLDSL PDFMQSPNQQ VKFHSAFPPL TTKVRVRGVM ERAGFDVYKP
EKDRSISSGT RSPRLNDLYH GDNGQFHPPN RLHSNRSSSS SQKSPNRVPL RSYSHNQMRT
ENTSSRSTTE YRSNASDNHE AGERFKNPSG KTRNFTTNPS NNSTPNLAHG FDKSTSSTHS
PVDSSSSPSS EIKKKNSILS YARQRLNLHT AKQNQTVPTA SPLQQNNYSS KEKTYPEPVV
PNLTLSDTPR HTIDSDLEYN PTDRVKLEPT ATLAYKSEAE GDFMSPPEDI WVEGSKRVHH
GAADELYSRQ VPQVNGPRPY YDSESDPNME EHTDIPLNFG NNQHPGGVPS ASQYAFTNPD
IVVSQPDGQN IDVYADDSRS YTKLSAPEQS NSRSLVPGSP AKSFKSESSV ESFDEKFMLH
GNDKEEDYTG DLSQETLGGL GGLRKTIQST ESEGMLPVVP NMKNIYNQDN KRISTLGTND
MKIYNLQSFD SEDTDDQQEL QVVNDNVVDF NQINEMSVIQ EGESEDRKSS LDMNDPYRSN
VPSEISKVLP DSSVARIPIL TINRDSSSED HDIASFKDAE QGDYDHEDGL FEAGKPSVAG
FTGHSANIVD TPSSSLNPFL PDSETPQPKA LNANGISDLI NDIDNFGLAS GGPNEEAEDY
RDADVSGEHY DTSQQTMGSF EIPPRHFEIQ QLQPHQHQHP HSHSSAASTS DTEAAHASHH
PYASLSHNSN TPSFGSTPLQ MSSGFTTPDK DINFEESKAS FITAHKELYY PPGEGPCRKC
GDIILDSEKK IWSKDNQLSG QWHRSCFGCH KCGSKFNKGS SCYVYGDQPY CERHFHELNG
SLCWICNKGV EGECLQNEIN EVFHIDCLKC VICGLNVEGD YFIFRDEVMC ETDAKELMYQ
IEEAEKEYQG KDVEKMIKRR TRVLYL
//
