ID A0A1E3NRB2_9ASCO Unreviewed; 726 AA.
AC A0A1E3NRB2;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=DUF676 domain-containing protein {ECO:0000259|Pfam:PF05057};
DE Flags: Fragment;
GN ORFNames=PICMEDRAFT_25204 {ECO:0000313|EMBL:ODQ48609.1};
OS Pichia membranifaciens NRRL Y-2026.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Pichiaceae; Pichia.
OX NCBI_TaxID=763406 {ECO:0000313|EMBL:ODQ48609.1, ECO:0000313|Proteomes:UP000094455};
RN [1] {ECO:0000313|EMBL:ODQ48609.1, ECO:0000313|Proteomes:UP000094455}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL Y-2026 {ECO:0000313|EMBL:ODQ48609.1,
RC ECO:0000313|Proteomes:UP000094455};
RX PubMed=27535936; DOI=10.1073/pnas.1603941113;
RA Riley R., Haridas S., Wolfe K.H., Lopes M.R., Hittinger C.T., Goeker M.,
RA Salamov A.A., Wisecaver J.H., Long T.M., Calvey C.H., Aerts A.L.,
RA Barry K.W., Choi C., Clum A., Coughlan A.Y., Deshpande S., Douglass A.P.,
RA Hanson S.J., Klenk H.-P., LaButti K.M., Lapidus A., Lindquist E.A.,
RA Lipzen A.M., Meier-Kolthoff J.P., Ohm R.A., Otillar R.P., Pangilinan J.L.,
RA Peng Y., Rokas A., Rosa C.A., Scheuner C., Sibirny A.A., Slot J.C.,
RA Stielow J.B., Sun H., Kurtzman C.P., Blackwell M., Grigoriev I.V.,
RA Jeffries T.W.;
RT "Comparative genomics of biotechnologically important yeasts.";
RL Proc. Natl. Acad. Sci. U.S.A. 113:9882-9887(2016).
CC -!- SIMILARITY: Belongs to the putative lipase ROG1 family.
CC {ECO:0000256|ARBA:ARBA00007920}.
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DR EMBL; KV454001; ODQ48609.1; -; Genomic_DNA.
DR RefSeq; XP_019019722.1; XM_019162385.1.
DR AlphaFoldDB; A0A1E3NRB2; -.
DR STRING; 763406.A0A1E3NRB2; -.
DR GeneID; 30179072; -.
DR OrthoDB; 1749646at2759; -.
DR Proteomes; UP000094455; Unassembled WGS sequence.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR007751; DUF676_lipase-like.
DR InterPro; IPR044294; Lipase-like.
DR InterPro; IPR016445; Rog1_fam.
DR PANTHER; PTHR12482:SF70; LIPASE ROG1-RELATED; 1.
DR PANTHER; PTHR12482; UNCHARACTERIZED; 1.
DR Pfam; PF05057; DUF676; 1.
DR PIRSF; PIRSF005412; UCP005412_abhydr; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000094455}.
FT DOMAIN 177..367
FT /note="DUF676"
FT /evidence="ECO:0000259|Pfam:PF05057"
FT REGION 657..695
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 676..695
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 726
FT /evidence="ECO:0000313|EMBL:ODQ48609.1"
SQ SEQUENCE 726 AA; 81905 MW; C787F53CF16C9F57 CRC64;
MTEEVLYKNT GTLKIGDVHR FVVTYTPTDI NKEIGTHLYV KVKNIENVLM NSVLLTGPYI
MYCDIRSAAY DHNVPCFVSD DQPAYDPNMI PGQSLVQRLT LNRLQAKYVW VVDVVSQIIF
STTASTGFEI LLARDEQSLH RNYSCLRNSN YSPSTLNIQH LTTADIWNRP PRSICDPIHL
VILVHGLHSN STADMFYMKD RLEGMADKTG ENLVIRAYSG NVCKTERGIK YLGRRLAEYI
VKDSLEGLNG MVEKISFISH SLGGPVQTFA ISYINFNYPD FFERIKPENF IAMASPMLGI
SNENPTYVKV FLKFGIVGKT GQDLNLDGAQ PMLLLLPSEP TRKILKAFKR RTVYANVLND
GIVPLRTSAL LYLDWKGLTK VYETLKNNAK KSSSGSSSST GYVADKAAEI PVDMNNDTMD
STDGDRTFVD SIKSRIQSTI GFCLPSIQAS KTTNKYSYFQ TTDMEVSDSE ATNDNTSTGM
DSANEALPSI PKSSALSSIK RVLLPPTPSS KYINDPKSRY DVILHDKIYT PDMIPKRHTT
LSKNVILSQL EQKKKHRYLE ETIARRWHQG MSWRKVLVYL QPDAHNNMVV RRRFANAYGW
QVIDHMVEEH FSKKCCMGED LSSWKIKKSD CNLIDLDEEE SRDLNVKLGQ VMNKEYRKES
KRHHINSPDL SVPERVNIDS DSNTSDLDND SANNGAWLNE EASGYYDGPT GLLNSVNEGV
AAWKES
//
