ID A0A1E3NSS9_9ASCO Unreviewed; 899 AA.
AC A0A1E3NSS9;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=Clp R domain-containing protein {ECO:0000259|PROSITE:PS51903};
GN ORFNames=PICMEDRAFT_14633 {ECO:0000313|EMBL:ODQ49159.1};
OS Pichia membranifaciens NRRL Y-2026.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Pichiaceae; Pichia.
OX NCBI_TaxID=763406 {ECO:0000313|EMBL:ODQ49159.1, ECO:0000313|Proteomes:UP000094455};
RN [1] {ECO:0000313|EMBL:ODQ49159.1, ECO:0000313|Proteomes:UP000094455}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL Y-2026 {ECO:0000313|EMBL:ODQ49159.1,
RC ECO:0000313|Proteomes:UP000094455};
RX PubMed=27535936; DOI=10.1073/pnas.1603941113;
RA Riley R., Haridas S., Wolfe K.H., Lopes M.R., Hittinger C.T., Goeker M.,
RA Salamov A.A., Wisecaver J.H., Long T.M., Calvey C.H., Aerts A.L.,
RA Barry K.W., Choi C., Clum A., Coughlan A.Y., Deshpande S., Douglass A.P.,
RA Hanson S.J., Klenk H.-P., LaButti K.M., Lapidus A., Lindquist E.A.,
RA Lipzen A.M., Meier-Kolthoff J.P., Ohm R.A., Otillar R.P., Pangilinan J.L.,
RA Peng Y., Rokas A., Rosa C.A., Scheuner C., Sibirny A.A., Slot J.C.,
RA Stielow J.B., Sun H., Kurtzman C.P., Blackwell M., Grigoriev I.V.,
RA Jeffries T.W.;
RT "Comparative genomics of biotechnologically important yeasts.";
RL Proc. Natl. Acad. Sci. U.S.A. 113:9882-9887(2016).
CC -!- SIMILARITY: Belongs to the ClpA/ClpB family.
CC {ECO:0000256|RuleBase:RU004432}.
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DR EMBL; KV454001; ODQ49159.1; -; Genomic_DNA.
DR RefSeq; XP_019020272.1; XM_019160461.1.
DR AlphaFoldDB; A0A1E3NSS9; -.
DR STRING; 763406.A0A1E3NSS9; -.
DR GeneID; 30177148; -.
DR OrthoDB; 35211at2759; -.
DR Proteomes; UP000094455; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR CDD; cd19499; RecA-like_ClpB_Hsp104-like; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 1.10.1780.10; Clp, N-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR019489; Clp_ATPase_C.
DR InterPro; IPR036628; Clp_N_dom_sf.
DR InterPro; IPR004176; Clp_R_dom.
DR InterPro; IPR001270; ClpA/B.
DR InterPro; IPR018368; ClpA/B_CS1.
DR InterPro; IPR028299; ClpA/B_CS2.
DR InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11638; ATP-DEPENDENT CLP PROTEASE; 1.
DR PANTHER; PTHR11638:SF194; HEAT SHOCK PROTEIN 104; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF07724; AAA_2; 1.
DR Pfam; PF17871; AAA_lid_9; 1.
DR Pfam; PF02861; Clp_N; 2.
DR Pfam; PF10431; ClpB_D2-small; 1.
DR PRINTS; PR00300; CLPPROTEASEA.
DR SMART; SM00382; AAA; 2.
DR SMART; SM01086; ClpB_D2-small; 1.
DR SUPFAM; SSF81923; Double Clp-N motif; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51903; CLP_R; 1.
DR PROSITE; PS00870; CLPAB_1; 1.
DR PROSITE; PS00871; CLPAB_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004432};
KW Chaperone {ECO:0000256|RuleBase:RU004432};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004432};
KW Reference proteome {ECO:0000313|Proteomes:UP000094455};
KW Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|PROSITE-
KW ProRule:PRU01251}.
FT DOMAIN 1..148
FT /note="Clp R"
FT /evidence="ECO:0000259|PROSITE:PS51903"
FT REGION 433..453
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 871..899
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 874..899
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 899 AA; 100390 MW; BC01EB36CA1FC840 CRC64;
MDSTQFTDRA LEIVTNAQKL CQQNSNPQLL PIHFLAAMIP DNESQAIYLK TIIEGSRYEW
EPVKRSINQH LLKLPSNQGS NMEPGMSASA ASIITNAEKV KQIQKDSYIG QDHILTAMLD
DDSIKRLFKD LSINTESLKK QIIQLRGSQR IDSRQADSSE EYEFLSKYAI DMTEQALQGK
IDPVIGREEE IRRAIRVLSR RAKSNPCLIG DPGVGKTSIV EGVAQRIVDN DVPSVLQNCK
LYGLDLGALK AGAKYQGEFE ERIKGVLNDI EKSKTMIILF IDEIHMLMGD GKSDAANLLK
PALARGHFHC IGATTISEYR KYIEKDGAFE RRFQRIDVKE PTVRETVAIL RGLQPRYEIH
HGVRILDSAL VTAAQLASRY LTYRKMPDSA VDLIDESAAG VAVARDSKPE ELDSKERQLE
LLEVEINALE RDKDADASTK DRLKQAHKKK QELEEELQPL REQYSQEKAG HQELTAAKKK
LDELDIKAQD AERRHDTATV ADIRMFAIPD VKKRIEELER EVEEEEHSAE FLVKNVVGPD
QVAETAARLT GIPVSKLTQA ENAKLINMER ELSSAVVGQG EAVKAVSNAI RLSRSGLANP
NQPASFLFLG LSGSGKTELA KKLAGFLFAD ERAMIRIDCS ELMEKHSVSK LIGTTAGYIG
FEEGGLLTNQ LMRKPYSVIL FDEVEKAAPE VLNILLQLLD DGRITAANGT LVNCSNAILI
LTSNLGAQFI NQSKVTKITP EVKEEVMTVV RQHFRPELLN RISATVVFNR LSRHAISKIV
KIRLEEIEKR FEENGRHLKL KLDDLAMEYL CKHGYSMDLG ARPLNRLIQN GVLNPLAVMI
LNGQVLDKED VKVSVNGKGL YVIPNHESSG EGMDVDAIED WTDDADEDDD YADNDVELD
//
