ID A0A1E3NSY7_9ASCO Unreviewed; 451 AA.
AC A0A1E3NSY7;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=GTP cyclohydrolase N-terminal domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=PICMEDRAFT_14723 {ECO:0000313|EMBL:ODQ49255.1};
OS Pichia membranifaciens NRRL Y-2026.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Pichiaceae; Pichia.
OX NCBI_TaxID=763406 {ECO:0000313|EMBL:ODQ49255.1, ECO:0000313|Proteomes:UP000094455};
RN [1] {ECO:0000313|EMBL:ODQ49255.1, ECO:0000313|Proteomes:UP000094455}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL Y-2026 {ECO:0000313|EMBL:ODQ49255.1,
RC ECO:0000313|Proteomes:UP000094455};
RX PubMed=27535936; DOI=10.1073/pnas.1603941113;
RA Riley R., Haridas S., Wolfe K.H., Lopes M.R., Hittinger C.T., Goeker M.,
RA Salamov A.A., Wisecaver J.H., Long T.M., Calvey C.H., Aerts A.L.,
RA Barry K.W., Choi C., Clum A., Coughlan A.Y., Deshpande S., Douglass A.P.,
RA Hanson S.J., Klenk H.-P., LaButti K.M., Lapidus A., Lindquist E.A.,
RA Lipzen A.M., Meier-Kolthoff J.P., Ohm R.A., Otillar R.P., Pangilinan J.L.,
RA Peng Y., Rokas A., Rosa C.A., Scheuner C., Sibirny A.A., Slot J.C.,
RA Stielow J.B., Sun H., Kurtzman C.P., Blackwell M., Grigoriev I.V.,
RA Jeffries T.W.;
RT "Comparative genomics of biotechnologically important yeasts.";
RL Proc. Natl. Acad. Sci. U.S.A. 113:9882-9887(2016).
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DR EMBL; KV454001; ODQ49255.1; -; Genomic_DNA.
DR RefSeq; XP_019020368.1; XM_019160499.1.
DR AlphaFoldDB; A0A1E3NSY7; -.
DR STRING; 763406.A0A1E3NSY7; -.
DR GeneID; 30177186; -.
DR OrthoDB; 46806at2759; -.
DR Proteomes; UP000094455; Unassembled WGS sequence.
DR Gene3D; 3.40.50.10990; GTP cyclohydrolase II; 1.
DR InterPro; IPR022163; GTP_CH_N.
DR InterPro; IPR032677; GTP_cyclohydro_II.
DR InterPro; IPR036144; RibA-like_sf.
DR PANTHER; PTHR47259; -; 1.
DR PANTHER; PTHR47259:SF2; URACIL-REGULATED PROTEIN 1; 1.
DR Pfam; PF12471; GTP_CH_N; 1.
DR Pfam; PF00925; GTP_cyclohydro2; 1.
DR SUPFAM; SSF142695; RibA-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000094455}.
FT DOMAIN 39..231
FT /note="GTP cyclohydrolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF12471"
FT DOMAIN 257..405
FT /note="GTP cyclohydrolase II"
FT /evidence="ECO:0000259|Pfam:PF00925"
SQ SEQUENCE 451 AA; 50118 MW; EA368735F372BDB7 CRC64;
MTSICNKSCE HQHGNIGIHE VSSTPIAVNS AFVDYFGEKM RLSTFTSDAD INPLPLNWSA
SASTARGPVV VSKYKDGMTK HNAIGAHAGP YSIYHALSIA SKQLDSMHEP DYTNAHPPHN
FPQQPQWSTP GKIVTMDPFG HMAPWIYGDL AKKENVDIKP TMSITKAILS IPEIKEEVKR
GNLVPDGKIV LNDEGEMACT KIAVDPVWHL PGVAERLNIT EDELRKALFQ DTNGMYPELI
SRPDIKVFCP PIGGITAYIF GDPDNLPKED KRLAVRVHDE CSGSDVFLSD ICSCRCYLIF
GLVEAAKEAQ KGGNGLVCYF RKEGRCLGEV TKYLVYNARK RGGDTADEYF HRTECIAGVK
DARFQELMPD ILHWLGITKI DRMLSMSNMK HDAIVDSGIT IDERVEIPDY LLPADSRVEI
DAKIAAGYFT NGHVYTTDEL KKVEGRKWEG L
//
