ID A0A1E3P4L4_WICAA Unreviewed; 507 AA.
AC A0A1E3P4L4;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE RecName: Full=Cdc23 domain-containing protein {ECO:0000259|Pfam:PF04049};
GN ORFNames=WICANDRAFT_53346 {ECO:0000313|EMBL:ODQ59822.1};
OS Wickerhamomyces anomalus (strain ATCC 58044 / CBS 1984 / NCYC 433 / NRRL
OS Y-366-8) (Yeast) (Hansenula anomala).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Phaffomycetaceae; Wickerhamomyces.
OX NCBI_TaxID=683960 {ECO:0000313|EMBL:ODQ59822.1, ECO:0000313|Proteomes:UP000094112};
RN [1] {ECO:0000313|EMBL:ODQ59822.1, ECO:0000313|Proteomes:UP000094112}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 58044 / CBS 1984 / NCYC 433 / NRRL Y-366-8
RC {ECO:0000313|Proteomes:UP000094112};
RX PubMed=27535936; DOI=10.1073/pnas.1603941113;
RA Riley R., Haridas S., Wolfe K.H., Lopes M.R., Hittinger C.T., Goeker M.,
RA Salamov A.A., Wisecaver J.H., Long T.M., Calvey C.H., Aerts A.L.,
RA Barry K.W., Choi C., Clum A., Coughlan A.Y., Deshpande S., Douglass A.P.,
RA Hanson S.J., Klenk H.-P., LaButti K.M., Lapidus A., Lindquist E.A.,
RA Lipzen A.M., Meier-Kolthoff J.P., Ohm R.A., Otillar R.P., Pangilinan J.L.,
RA Peng Y., Rokas A., Rosa C.A., Scheuner C., Sibirny A.A., Slot J.C.,
RA Stielow J.B., Sun H., Kurtzman C.P., Blackwell M., Grigoriev I.V.,
RA Jeffries T.W.;
RT "Comparative genomics of biotechnologically important yeasts.";
RL Proc. Natl. Acad. Sci. U.S.A. 113:9882-9887(2016).
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DR EMBL; KV454210; ODQ59822.1; -; Genomic_DNA.
DR RefSeq; XP_019039029.1; XM_019182711.1.
DR AlphaFoldDB; A0A1E3P4L4; -.
DR STRING; 683960.A0A1E3P4L4; -.
DR GeneID; 30199957; -.
DR OrthoDB; 3131281at2759; -.
DR Proteomes; UP000094112; Unassembled WGS sequence.
DR GO; GO:0005680; C:anaphase-promoting complex; IEA:InterPro.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR InterPro; IPR007192; APC8.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR12558; CELL DIVISION CYCLE 16,23,27; 1.
DR PANTHER; PTHR12558:SF10; CELL DIVISION CYCLE PROTEIN 23 HOMOLOG; 1.
DR Pfam; PF04049; ANAPC8; 1.
DR Pfam; PF13432; TPR_16; 1.
DR Pfam; PF13181; TPR_8; 2.
DR SMART; SM00028; TPR; 5.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50005; TPR; 3.
PE 4: Predicted;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Mitosis {ECO:0000256|ARBA:ARBA00022776};
KW Reference proteome {ECO:0000313|Proteomes:UP000094112};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT DOMAIN 12..217
FT /note="Cdc23"
FT /evidence="ECO:0000259|Pfam:PF04049"
FT REPEAT 312..345
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 346..379
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 380..413
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
SQ SEQUENCE 507 AA; 59183 MW; 5899515C7EA2B976 CRC64;
MISIDHIPKY KLQVSKSEQD VFALAKTYFD CKEFDRCAHV LKNCKSQDVL FIRLYAMFLS
GEKKKEEESE GVLGLHDHSS VNTSVSLILK ELESILEQEP NGLKSPFLNW LHGVVLVKHK
SMAAAKDAFI RSLAQYPYNW SCWAELLFCL PTFGEGMDVL SSLELQFQDN FAELIMLKFA
KVVINQQCFQ QTAELKTMLD SLIVKFPKFS FLKTQHALIC YHALKYNIAE ELFDEILVND
PLRLDEMDIY SNILYVMDKR SKLAFLAQFA CAIDKFRPET CCIVANYYSM KFEHEKAIMY
YRRALTLNRN SLSAWTLMGH EFVELKNTHA AIESYRRAVD TNYKDFKAWY GLGQAYEILD
MHLYSLYYYQ KAASLNPLDQ RVWEALGNCY EKLDKIRDSI TCYQKAINLN EVKNVSHLYK
LALLYEKLQD PAKTYDYMFQ CYQEEINEGV RNDETAKARL WLAKYETRNQ NWEAAHKYAV
DLTHGTGQEI EEARAVARET RNRINLQ
//
