ID   A0A1E3PEL1_9ASCO        Unreviewed;      1124 AA.
AC   A0A1E3PEL1;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=RING-type domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=NADFUDRAFT_53304 {ECO:0000313|EMBL:ODQ63644.1};
OS   Nadsonia fulvescens var. elongata DSM 6958.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetales incertae sedis; Nadsonia.
OX   NCBI_TaxID=857566 {ECO:0000313|EMBL:ODQ63644.1, ECO:0000313|Proteomes:UP000095009};
RN   [1] {ECO:0000313|EMBL:ODQ63644.1, ECO:0000313|Proteomes:UP000095009}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 6958 {ECO:0000313|EMBL:ODQ63644.1,
RC   ECO:0000313|Proteomes:UP000095009};
RX   PubMed=27535936; DOI=10.1073/pnas.1603941113;
RA   Riley R., Haridas S., Wolfe K.H., Lopes M.R., Hittinger C.T., Goeker M.,
RA   Salamov A.A., Wisecaver J.H., Long T.M., Calvey C.H., Aerts A.L.,
RA   Barry K.W., Choi C., Clum A., Coughlan A.Y., Deshpande S., Douglass A.P.,
RA   Hanson S.J., Klenk H.-P., LaButti K.M., Lapidus A., Lindquist E.A.,
RA   Lipzen A.M., Meier-Kolthoff J.P., Ohm R.A., Otillar R.P., Pangilinan J.L.,
RA   Peng Y., Rokas A., Rosa C.A., Scheuner C., Sibirny A.A., Slot J.C.,
RA   Stielow J.B., Sun H., Kurtzman C.P., Blackwell M., Grigoriev I.V.,
RA   Jeffries T.W.;
RT   "Comparative genomics of biotechnologically important yeasts.";
RL   Proc. Natl. Acad. Sci. U.S.A. 113:9882-9887(2016).
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DR   EMBL; KV454414; ODQ63644.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1E3PEL1; -.
DR   STRING; 857566.A0A1E3PEL1; -.
DR   OrthoDB; 2056454at2759; -.
DR   Proteomes; UP000095009; Unassembled WGS sequence.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR002035; VWF_A.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   PANTHER; PTHR10579; CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR; 1.
DR   PANTHER; PTHR10579:SF43; LOW QUALITY PROTEIN: EPITHELIAL CHLORIDE CHANNEL PROTEIN-LIKE ISOFORM X1-RELATED; 1.
DR   Pfam; PF15411; PH_10; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   SUPFAM; SSF57850; RING/U-box; 1.
DR   SUPFAM; SSF53300; vWA-like; 1.
DR   PROSITE; PS50234; VWFA; 1.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00175};
KW   Reference proteome {ECO:0000313|Proteomes:UP000095009};
KW   Zinc {ECO:0000256|PROSITE-ProRule:PRU00175};
KW   Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00175}.
FT   DOMAIN          157..212
FT                   /note="RING-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50089"
FT   DOMAIN          576..754
FT                   /note="VWFA"
FT                   /evidence="ECO:0000259|PROSITE:PS50234"
FT   REGION          1..131
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          544..571
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        14..37
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        49..73
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1124 AA;  125136 MW;  4ED4D65F5DA15BD9 CRC64;
     MSPILPKLEM PSGPSTPLSI STTSSSLHSA SLGSHNPYFT PPSPPSLSPR SIFKRTFSSP
     TKIRKSSWTA ATSPPPKPHE KENSFPFLLN PRTAYPRSLS VNDIPPVPQP PSSPGDHSST
     SHANTPPKIE PYIMSSNHRL ATPSTNHDLR KRDPHCCVFC QESLIYTFCG ERILTLQCSH
     VAHQECFSQL ISIAGLAASD PRLSLPTCPI CTTKSELTNE KMWQDMYDKK LIEWVLSPPS
     PPPIINIPKK NEASKHAEQI RYTAQNKYFT QLEHEPVDNL PLTPPRSISP LIEKPQAPEP
     EYLYSPTPYI PPPAETAGVD FHLIFSPLAL EKTPASSVGA SPDSSSVELP EIQTQNNRTA
     KLASPTVTVT PEYTKVFTPF VTCVVEVRVP IDYYSSPQVT FPTEKSKLKK MQTQASDLFK
     GMHDWHGLDP TQFGDLILVD EFQVSKNLDT WQSLKCYLFE LILICATPAS DDGNSEKERS
     NCYRLKGSMV LHRHLNSVFP ATSSSNVLSI LLDTPSLPQL HLSHHDMKVL DKWYHKLIEV
     KQEKSPIKSK RESELKPASL SPPISPSHLP TRPPLDLVVA APIYGTSKGN MKFKHIRASL
     RYLISKLSSQ DRLGVIMYGN DAQTSFAIGM ASPAWPGWTH TIQHIKPATS TSAGMDHNDV
     FEGAVGALKL LRARHTKNPV AGCMLLSDSA LTRSDQTRMR KLLREGDDDI SIHTFGIDIS
     HSEDALVDIA RATRGRYVYV RDWPDLAPCL ANALKYQQSY THKNVKINLA AGSQFRFAYL
     MGTDNDHEGP IVGDHESKFQ SINLGNLAAG QKRSFLVQVI KDQPSSRHNS NEWSSLIHSL
     DKALGDENDT TTVNLFDTTV NYGSFSNFNS SSELNSVAVD CGPTKIELAS NLHDIDFYKR
     HSQSDSASDY EINLSPIQKQ NESVFKIDDH RLSTYSFIQH EHVRLLKSPL SPRSALSPLS
     PLSPLSPLSP LFAENMCFLG SNLTDPHTPL FLLNDHYQGQ PRASDGRVVA RRVELIFVHT
     LNEIIYGFEN NNGEDERCRI VAGARHLIAG HRRCLSDNHN QTTDSGALKT IKKIDAELAW
     IVDDSRNKSS VVFNHDVKKW LKQVRLNVWL YNGATSISRT KPQS
//