ID A0A1E3PHE4_9ASCO Unreviewed; 646 AA.
AC A0A1E3PHE4;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=p-loop containing nucleoside triphosphate hydrolase protein {ECO:0000313|EMBL:ODQ64846.1};
DE Flags: Fragment;
GN ORFNames=NADFUDRAFT_83024 {ECO:0000313|EMBL:ODQ64846.1};
OS Nadsonia fulvescens var. elongata DSM 6958.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetales incertae sedis; Nadsonia.
OX NCBI_TaxID=857566 {ECO:0000313|EMBL:ODQ64846.1, ECO:0000313|Proteomes:UP000095009};
RN [1] {ECO:0000313|EMBL:ODQ64846.1, ECO:0000313|Proteomes:UP000095009}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 6958 {ECO:0000313|EMBL:ODQ64846.1,
RC ECO:0000313|Proteomes:UP000095009};
RX PubMed=27535936; DOI=10.1073/pnas.1603941113;
RA Riley R., Haridas S., Wolfe K.H., Lopes M.R., Hittinger C.T., Goeker M.,
RA Salamov A.A., Wisecaver J.H., Long T.M., Calvey C.H., Aerts A.L.,
RA Barry K.W., Choi C., Clum A., Coughlan A.Y., Deshpande S., Douglass A.P.,
RA Hanson S.J., Klenk H.-P., LaButti K.M., Lapidus A., Lindquist E.A.,
RA Lipzen A.M., Meier-Kolthoff J.P., Ohm R.A., Otillar R.P., Pangilinan J.L.,
RA Peng Y., Rokas A., Rosa C.A., Scheuner C., Sibirny A.A., Slot J.C.,
RA Stielow J.B., Sun H., Kurtzman C.P., Blackwell M., Grigoriev I.V.,
RA Jeffries T.W.;
RT "Comparative genomics of biotechnologically important yeasts.";
RL Proc. Natl. Acad. Sci. U.S.A. 113:9882-9887(2016).
CC -!- SIMILARITY: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1
CC subfamily. {ECO:0000256|ARBA:ARBA00008959}.
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DR EMBL; KV454410; ODQ64846.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1E3PHE4; -.
DR STRING; 857566.A0A1E3PHE4; -.
DR OrthoDB; 206891at2759; -.
DR Proteomes; UP000095009; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0006271; P:DNA strand elongation involved in DNA replication; IEA:UniProt.
DR CDD; cd00009; AAA; 1.
DR CDD; cd18139; HLD_clamp_RarA; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 1.20.272.10; -; 1.
DR Gene3D; 1.10.3710.10; DNA polymerase III clamp loader subunits, C-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR008921; DNA_pol3_clamp-load_cplx_C.
DR InterPro; IPR021886; MgsA_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13779:SF7; ATPASE WRNIP1; 1.
DR PANTHER; PTHR13779; WERNER HELICASE-INTERACTING PROTEIN 1 FAMILY MEMBER; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF12002; MgsA_C; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48019; post-AAA+ oligomerization domain-like; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Hydrolase {ECO:0000313|EMBL:ODQ64846.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000095009}.
FT DOMAIN 276..393
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT REGION 116..155
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 137..155
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 646
FT /evidence="ECO:0000313|EMBL:ODQ64846.1"
SQ SEQUENCE 646 AA; 72322 MW; 022016531E0792C0 CRC64;
MIMKELKEDS SNEPENKIVQ LLTDSENEIS RNLSTSAFDI ISDSDNDDDD IIKIQGSIIV
QQDSPGKSIK EGHQSALNLN TLPLREDTYL TKEIDIELSQ DRKDIETRCT LGITPSKFPS
KIESDDRKDE NLTIPPPQLL VHSNDETCEK SPNMKTSNYD INRSCLLKCP GTPTKSRNSS
SRISEANSDQ VDIYLTDFTE QKTLSRSNSV TPDISQPSVE KKKCELTNIS KILSENITGT
IPLAEQTRPT ELDDFIGQDQ LMGRGGILRS LIEQDEIPSM ILWGPCGVGK TTLARIIAQK
TKSRFIELSA THLTMNGCHR VFDQARKEKI TNCRETILFL DEIHSFSKTQ QDVLLPAVEN
GDIILIGATT ENPSLKVANA LTSRCKVFTL NTLTESEIYT VLQRALSVFN EKRRKGNLRE
IKFDEDSLKY FLEFSNGDGR FIISTLEMTI KHFLYLESKS QKKAVLEYPN ISECVINIKT
TKVLLASLRV KKRKANLPEF LSAIRNSIRG SNADAALYYL NTLILSEQDP TDIADCFIRI
AMEDIGNADE SCLSFASSTQ QVVYMLGMPE AEMALANCCV KLAQAPKGKM VYQVKEKVKN
FLIENDGASS ASVPLHLKNA PNELMKRQGH GKGYKYNPDY IDGKVK
//
