ID A0A1E3PHE6_9ASCO Unreviewed; 644 AA.
AC A0A1E3PHE6;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=WD40 repeat-like protein {ECO:0000313|EMBL:ODQ64634.1};
GN ORFNames=NADFUDRAFT_52265 {ECO:0000313|EMBL:ODQ64634.1};
OS Nadsonia fulvescens var. elongata DSM 6958.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetales incertae sedis; Nadsonia.
OX NCBI_TaxID=857566 {ECO:0000313|EMBL:ODQ64634.1, ECO:0000313|Proteomes:UP000095009};
RN [1] {ECO:0000313|EMBL:ODQ64634.1, ECO:0000313|Proteomes:UP000095009}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 6958 {ECO:0000313|EMBL:ODQ64634.1,
RC ECO:0000313|Proteomes:UP000095009};
RX PubMed=27535936; DOI=10.1073/pnas.1603941113;
RA Riley R., Haridas S., Wolfe K.H., Lopes M.R., Hittinger C.T., Goeker M.,
RA Salamov A.A., Wisecaver J.H., Long T.M., Calvey C.H., Aerts A.L.,
RA Barry K.W., Choi C., Clum A., Coughlan A.Y., Deshpande S., Douglass A.P.,
RA Hanson S.J., Klenk H.-P., LaButti K.M., Lapidus A., Lindquist E.A.,
RA Lipzen A.M., Meier-Kolthoff J.P., Ohm R.A., Otillar R.P., Pangilinan J.L.,
RA Peng Y., Rokas A., Rosa C.A., Scheuner C., Sibirny A.A., Slot J.C.,
RA Stielow J.B., Sun H., Kurtzman C.P., Blackwell M., Grigoriev I.V.,
RA Jeffries T.W.;
RT "Comparative genomics of biotechnologically important yeasts.";
RL Proc. Natl. Acad. Sci. U.S.A. 113:9882-9887(2016).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; KV454411; ODQ64634.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1E3PHE6; -.
DR STRING; 857566.A0A1E3PHE6; -.
DR OrthoDB; 5481136at2759; -.
DR Proteomes; UP000095009; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0003714; F:transcription corepressor activity; IEA:InterPro.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 1.20.960.30; -; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR024977; Apc4-like_WD40_dom.
DR InterPro; IPR045183; Ebi-like.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR006594; LisH.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR22846:SF2; F-BOX-LIKE_WD REPEAT-CONTAINING PROTEIN EBI; 1.
DR PANTHER; PTHR22846; WD40 REPEAT PROTEIN; 1.
DR Pfam; PF12894; ANAPC4_WD40; 1.
DR Pfam; PF08513; LisH; 1.
DR Pfam; PF00400; WD40; 4.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00667; LisH; 1.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50896; LISH; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 4.
DR PROSITE; PS50294; WD_REPEATS_REGION; 4.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000095009};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 273..328
FT /note="Anaphase-promoting complex subunit 4-like WD40"
FT /evidence="ECO:0000259|Pfam:PF12894"
FT REPEAT 273..307
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 314..355
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 418..459
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 518..559
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 137..159
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 137..158
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 644 AA; 70881 MW; 44C4E0AD9F99EE5A CRC64;
MSITSRELNY LIWRYLQENG FENSTFAMQQ EAKADELEED FGSKIPAGTL VRIVQKGLLY
SEIESSIRED GTIDKENTPK PTLFGDLRNT SNNDEDFKDN LMDVDDDDEA LIKELMKHAN
VLTRGNNIQK SIKEIEQQKT DDHKNNETLN DDRDDNSSNL QRTCAIQGEP GNKSKTNSQD
LLMKSTIVSS LNTDVSRVDS EVQVNLSREF RPMGVLPLLV SLPPYQECAW NPQDTTKFAV
GSADSKVLIS TLIKESNDDR YSVSSIQLSH PVTENIDKDI TQVVWNNTGT LLVTAGYDGQ
MRLWTVDGKL RHILSLHRAP VLCVRWNKSG SLILSVDCTN TVVVWDVFSG DVRQNFTHAS
IPKYEDTLIV PDSMNSLSTD ISIGTSADWI DGVTYATTSD PSIITIYKLG EKMPMLRFRG
HSQGINSLRF DPVSLLLASA SDDHTVRIWH GKSTSSFAVL TGHSAPVQHV RWLVSKDCTA
PPISTDLVAP TSKLITVSLD GTLHIWDVSR GGICLCILIL HKKAILSCEV SPDGKYIASG
GLDGVVVVWD VHDFSLLETP AHAIDGESME KGSNRAVGKY DLLDLIDKRA SSDSSISGSE
VTIDSHSNPV ITALSWSSDS SKILVGSSIG AAIIDWKHVS NTLA
//
