ID A0A1E3PHN9_9ASCO Unreviewed; 742 AA.
AC A0A1E3PHN9;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE RecName: Full=Anaphase-promoting complex subunit 2 {ECO:0000256|ARBA:ARBA00016068};
GN ORFNames=NADFUDRAFT_83685 {ECO:0000313|EMBL:ODQ64820.1};
OS Nadsonia fulvescens var. elongata DSM 6958.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetales incertae sedis; Nadsonia.
OX NCBI_TaxID=857566 {ECO:0000313|EMBL:ODQ64820.1, ECO:0000313|Proteomes:UP000095009};
RN [1] {ECO:0000313|EMBL:ODQ64820.1, ECO:0000313|Proteomes:UP000095009}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 6958 {ECO:0000313|EMBL:ODQ64820.1,
RC ECO:0000313|Proteomes:UP000095009};
RX PubMed=27535936; DOI=10.1073/pnas.1603941113;
RA Riley R., Haridas S., Wolfe K.H., Lopes M.R., Hittinger C.T., Goeker M.,
RA Salamov A.A., Wisecaver J.H., Long T.M., Calvey C.H., Aerts A.L.,
RA Barry K.W., Choi C., Clum A., Coughlan A.Y., Deshpande S., Douglass A.P.,
RA Hanson S.J., Klenk H.-P., LaButti K.M., Lapidus A., Lindquist E.A.,
RA Lipzen A.M., Meier-Kolthoff J.P., Ohm R.A., Otillar R.P., Pangilinan J.L.,
RA Peng Y., Rokas A., Rosa C.A., Scheuner C., Sibirny A.A., Slot J.C.,
RA Stielow J.B., Sun H., Kurtzman C.P., Blackwell M., Grigoriev I.V.,
RA Jeffries T.W.;
RT "Comparative genomics of biotechnologically important yeasts.";
RL Proc. Natl. Acad. Sci. U.S.A. 113:9882-9887(2016).
CC -!- SIMILARITY: Belongs to the cullin family. {ECO:0000256|PROSITE-
CC ProRule:PRU00330, ECO:0000256|RuleBase:RU003829}.
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DR EMBL; KV454411; ODQ64820.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1E3PHN9; -.
DR STRING; 857566.A0A1E3PHN9; -.
DR OrthoDB; 2786196at2759; -.
DR Proteomes; UP000095009; Unassembled WGS sequence.
DR GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR Gene3D; 1.20.1310.10; Cullin Repeats; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR044554; APC2-like.
DR InterPro; IPR014786; APC2_C.
DR InterPro; IPR016158; Cullin_homology.
DR InterPro; IPR036317; Cullin_homology_sf.
DR InterPro; IPR001373; Cullin_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR45957; ANAPHASE-PROMOTING COMPLEX SUBUNIT 2; 1.
DR PANTHER; PTHR45957:SF1; ANAPHASE-PROMOTING COMPLEX SUBUNIT 2; 1.
DR Pfam; PF08672; ANAPC2; 1.
DR Pfam; PF00888; Cullin; 1.
DR SMART; SM01013; APC2; 1.
DR SMART; SM00182; CULLIN; 1.
DR SUPFAM; SSF75632; Cullin homology domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50069; CULLIN_2; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Mitosis {ECO:0000256|ARBA:ARBA00022776};
KW Reference proteome {ECO:0000313|Proteomes:UP000095009};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT DOMAIN 424..624
FT /note="Cullin family profile"
FT /evidence="ECO:0000259|PROSITE:PS50069"
SQ SEQUENCE 742 AA; 85084 MW; 20A044DB7E232262 CRC64;
MTAVNRSIFD SVFSSSDLLF DDVEGYLPAV DTVAALEILK RWMAPKDQLY APTDDVLRAA
EYLRFFEDQL MAWYTDEFRL HFNKYAVPML YVNERHADQQ ENARYIAQIS NTLHDAHKHY
FHPLTYLELS DDITDCFQRS FNALVCYSLP TPFFYRSLKD YFRCFPIISD YTTSIPICEG
FYVAGLRDTV ERALAETAVV EMEIHIKEQY TAEWALSVLE HFESWLTHHL TASLEALLGR
KSQFRADLLA IGLGLLGNLR TNELFDIVVD YPDSTPALDD IKRCLRTPTE RAKVVNSFQI
ACVKRLLHPG ANTVDIVVAY LNTIRAFMIL DPRGVLLAKI SRPIRRYLKE REDTVGVIVA
GMLGTDDTDL KVLHEELSQH GNKYAQNSHG EVDDLKDLNW CPDPIDAPLD FKHVGRANDM
IGSLLSLYEN KDVFVREFVV IFANRLLESE DYNIDQAVIH LELLKLRFGE QELLNLDIMI
RDIAESKRVN SSLHGKSMEI NTSSSSRPST LWGGFNAKIL SRLFWPNFND VPFLIPQIIK
DQADKYSQGF EKLKQGRKLR WLNHIGSVKV ELELEDRSLD FVVTPEQASV IELFQHQPRL
SLLEVTNQLQ AKSDLALRAI RFWVSKGVLK DHGTQEDVFI VLERAEEKTN VNGGVVESFS
SAAIQSTEEA SSEEMRVYWS YIVGMLTNLG SMPLDRIQSF LRMLVPQDNP YTRSQDELQL
FLDLMVEEEQ LEVSGDGYRL KK
//
