ID A0A1E3Q2N2_LIPST Unreviewed; 609 AA.
AC A0A1E3Q2N2;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 22-FEB-2023, entry version 21.
DE RecName: Full=NUC153 domain-containing protein {ECO:0000259|Pfam:PF08159};
GN ORFNames=LIPSTDRAFT_4309 {ECO:0000313|EMBL:ODQ71943.1};
OS Lipomyces starkeyi NRRL Y-11557.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Lipomycetaceae; Lipomyces.
OX NCBI_TaxID=675824 {ECO:0000313|EMBL:ODQ71943.1, ECO:0000313|Proteomes:UP000094385};
RN [1] {ECO:0000313|EMBL:ODQ71943.1, ECO:0000313|Proteomes:UP000094385}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL Y-11557 {ECO:0000313|EMBL:ODQ71943.1,
RC ECO:0000313|Proteomes:UP000094385};
RX PubMed=27535936; DOI=10.1073/pnas.1603941113;
RA Riley R., Haridas S., Wolfe K.H., Lopes M.R., Hittinger C.T., Goeker M.,
RA Salamov A.A., Wisecaver J.H., Long T.M., Calvey C.H., Aerts A.L.,
RA Barry K.W., Choi C., Clum A., Coughlan A.Y., Deshpande S., Douglass A.P.,
RA Hanson S.J., Klenk H.-P., LaButti K.M., Lapidus A., Lindquist E.A.,
RA Lipzen A.M., Meier-Kolthoff J.P., Ohm R.A., Otillar R.P., Pangilinan J.L.,
RA Peng Y., Rokas A., Rosa C.A., Scheuner C., Sibirny A.A., Slot J.C.,
RA Stielow J.B., Sun H., Kurtzman C.P., Blackwell M., Grigoriev I.V.,
RA Jeffries T.W.;
RT "Comparative genomics of biotechnologically important yeasts.";
RL Proc. Natl. Acad. Sci. U.S.A. 113:9882-9887(2016).
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}.
CC -!- SIMILARITY: Belongs to the ESF1 family.
CC {ECO:0000256|ARBA:ARBA00009087}.
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DR EMBL; KV454296; ODQ71943.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1E3Q2N2; -.
DR STRING; 675824.A0A1E3Q2N2; -.
DR OrthoDB; 131620at2759; -.
DR Proteomes; UP000094385; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0006364; P:rRNA processing; IEA:InterPro.
DR InterPro; IPR039754; Esf1.
DR InterPro; IPR012580; NUC153.
DR PANTHER; PTHR12202:SF0; ESF1 HOMOLOG; 1.
DR PANTHER; PTHR12202; UNCHARACTERIZED; 1.
DR Pfam; PF08159; NUC153; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000094385}.
FT DOMAIN 560..588
FT /note="NUC153"
FT /evidence="ECO:0000259|Pfam:PF08159"
FT REGION 1..41
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 114..149
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 210..243
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 425..508
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 130..149
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 229..243
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 432..449
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 456..508
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 609 AA; 70872 MW; 64DEE473FF062171 CRC64;
MAKRKSSNVG LSEQSKKPVT TDPRFAIVHS DPRFAPPKKK DSKIVLDRRF KSKLSTDSEF
RQRRVVDRYG RKVEHDAAEK ELKRYYRLHD DHDHYLEDNE EGVEWKEEDE GGLFGKRYDP
ARGEGLIASS SDEEDTEEEV DEDEDGFAPL IQDEVIARGD ETSTFAVVNM DWENVRAADL
MVAFSSFVSA SGKILSISIY PSEFGKEQMA REELEGPPRE IFQKNGPTND EDEEEDEEDE
VNEKTIVRED SGEEFDSSKL RKYQLQRLRY YYAIVKCDSI VTARKIYDGC DGTEYEATSN
FFDLRYVPED MEFDEKPKEV CTRVPAVYRP NEFVTDALQH SKVKLTWDQT PNERLQFARR
AFSRREIEEM DFKAYLASSD SEVDDEEIGD DKEKLREKYR SLLLESQNNT GFDSKEDVDM
EITFTPGLSA DVESKEPEEE TTIEKYKRKE KERKKQRLEQ HRNKTGAGEK SLVDSSFKED
SSKESRGKKG VKKSKEERTE EERKKAELEL LMMGEDENSN LKHFDMRDIV KAEKQKKNKN
LRRKGKASEP VDDFSIDVKD ARFSALYDHH EFAIDPSRPQ FKETTAMTKL LDETRRRRQK
GADHELPES
//
