ID   A0A1E3QDL5_LIPST        Unreviewed;      1056 AA.
AC   A0A1E3QDL5;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   13-SEP-2023, entry version 20.
DE   RecName: Full=Tuberous sclerosis 1 {ECO:0008006|Google:ProtNLM};
GN   ORFNames=LIPSTDRAFT_110001 {ECO:0000313|EMBL:ODQ75182.1};
OS   Lipomyces starkeyi NRRL Y-11557.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Lipomycetaceae; Lipomyces.
OX   NCBI_TaxID=675824 {ECO:0000313|EMBL:ODQ75182.1, ECO:0000313|Proteomes:UP000094385};
RN   [1] {ECO:0000313|EMBL:ODQ75182.1, ECO:0000313|Proteomes:UP000094385}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL Y-11557 {ECO:0000313|EMBL:ODQ75182.1,
RC   ECO:0000313|Proteomes:UP000094385};
RX   PubMed=27535936; DOI=10.1073/pnas.1603941113;
RA   Riley R., Haridas S., Wolfe K.H., Lopes M.R., Hittinger C.T., Goeker M.,
RA   Salamov A.A., Wisecaver J.H., Long T.M., Calvey C.H., Aerts A.L.,
RA   Barry K.W., Choi C., Clum A., Coughlan A.Y., Deshpande S., Douglass A.P.,
RA   Hanson S.J., Klenk H.-P., LaButti K.M., Lapidus A., Lindquist E.A.,
RA   Lipzen A.M., Meier-Kolthoff J.P., Ohm R.A., Otillar R.P., Pangilinan J.L.,
RA   Peng Y., Rokas A., Rosa C.A., Scheuner C., Sibirny A.A., Slot J.C.,
RA   Stielow J.B., Sun H., Kurtzman C.P., Blackwell M., Grigoriev I.V.,
RA   Jeffries T.W.;
RT   "Comparative genomics of biotechnologically important yeasts.";
RL   Proc. Natl. Acad. Sci. U.S.A. 113:9882-9887(2016).
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DR   EMBL; KV454291; ODQ75182.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1E3QDL5; -.
DR   STRING; 675824.A0A1E3QDL5; -.
DR   OrthoDB; 2048425at2759; -.
DR   Proteomes; UP000094385; Unassembled WGS sequence.
DR   InterPro; IPR007483; Hamartin.
DR   PANTHER; PTHR15154; HAMARTIN; 1.
DR   PANTHER; PTHR15154:SF2; HAMARTIN; 1.
DR   Pfam; PF04388; Hamartin; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000094385}.
FT   REGION          313..342
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          534..553
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          618..668
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          733..779
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          994..1053
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        327..342
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        620..661
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        747..779
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1056 AA;  118416 MW;  7F086DC8DA548997 CRC64;
     MSGSLRDLSK AVTAALSSAD LPLTGDQRVE LPNTLCGSLT AYINKHDKYE ASDAQKLHEE
     LVNAYRTYVV SPDSSQESRF LQIILQLIPN VTPHQDGVKF WIEQFVLPAI DSAGKSRVIV
     EDARAFLFNI MVYDADDESI DLQLREALSD FVADVLVRIY VGKRQLVGVI RTSMTEYAGD
     DVAERQVICM QNAESELRRF GNKRPKAFFN VLDQYFVKKE YRVAILSLLC SFMQAQPPHL
     FETHSSKLVG HLYKCLLHDR SAVAVNLACT VFVMLLPHIC SILGPDLPKV FAVYARMMYW
     DILYKKEFAA PGDDAEEDGR AQKGLDDLGS SKSSDDASSP SSTMSYGGYY YYDDTEGKEL
     GQGSLMKVIK PQAEQETWDI LDGSFDDPAG AGPDSLTVNY SRIFTFIYGL YPIHFLTFLT
     SPRRYFRMRS AEMSDYIKYD IDDIALRSQI MSRRHLLHPN FFRYTFESEI SDRQRWDLAG
     TAEDVAAFCI TLDTKNLEMP EMQEPTVIFR GFHDHREHST EDQLPAYMSL DESAQTHAEN
     VPPDERPSDS GTAEVQDVMH RDEAFSVIDA LDEIPEDSYL FPADDNIGRA SESASIATGS
     DDHSTGVRIS APIVEPLMGK GFQSTSSESE RSKAAASPSF KPQTPIAASV SSISGSGEMS
     PGGSTHRPIM DIESILENHR DINSLVMSRR GSAETASLGM SSPVYRSQQH GSLSESISSL
     KLPAPITNVN TNIGPEIEHT TSHEEGQRHT SVASSIKSLP LSPKTQSSPG VSRQNPKSPI
     SFMQLSHSHF LGSSSIAANT VSNTGPSQDL KAPVQVPVAY LQRQLLVLRN ELNFERYLKQ
     LRLRNLRRLK EQYSILQRDD ANTQGLLLSN RMLQTKIERL QTDAKKQHAT LTTLATDRAK
     YSNQLLQKNR DLKAERDQWK TEEDGVRGAL EASRQEVEML KQGFLEKEAE IERVGRRLKD
     AMTTASEVES LRKKYTVLQS RVLEMYARDE RTSKAPLTDE NEELQNRIAK LELRVKAAES
     ESQQLEKQYS SRVEELEEEL TEIKSRIQTG QKSGVL
//