ID A0A1E3QEV0_LIPST Unreviewed; 530 AA.
AC A0A1E3QEV0;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=ENTH domain-containing protein {ECO:0000259|PROSITE:PS50942};
GN ORFNames=LIPSTDRAFT_101524 {ECO:0000313|EMBL:ODQ76223.1};
OS Lipomyces starkeyi NRRL Y-11557.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Lipomycetaceae; Lipomyces.
OX NCBI_TaxID=675824 {ECO:0000313|EMBL:ODQ76223.1, ECO:0000313|Proteomes:UP000094385};
RN [1] {ECO:0000313|EMBL:ODQ76223.1, ECO:0000313|Proteomes:UP000094385}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL Y-11557 {ECO:0000313|EMBL:ODQ76223.1,
RC ECO:0000313|Proteomes:UP000094385};
RX PubMed=27535936; DOI=10.1073/pnas.1603941113;
RA Riley R., Haridas S., Wolfe K.H., Lopes M.R., Hittinger C.T., Goeker M.,
RA Salamov A.A., Wisecaver J.H., Long T.M., Calvey C.H., Aerts A.L.,
RA Barry K.W., Choi C., Clum A., Coughlan A.Y., Deshpande S., Douglass A.P.,
RA Hanson S.J., Klenk H.-P., LaButti K.M., Lapidus A., Lindquist E.A.,
RA Lipzen A.M., Meier-Kolthoff J.P., Ohm R.A., Otillar R.P., Pangilinan J.L.,
RA Peng Y., Rokas A., Rosa C.A., Scheuner C., Sibirny A.A., Slot J.C.,
RA Stielow J.B., Sun H., Kurtzman C.P., Blackwell M., Grigoriev I.V.,
RA Jeffries T.W.;
RT "Comparative genomics of biotechnologically important yeasts.";
RL Proc. Natl. Acad. Sci. U.S.A. 113:9882-9887(2016).
CC -!- SIMILARITY: Belongs to the epsin family.
CC {ECO:0000256|ARBA:ARBA00010130}.
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DR EMBL; KV454289; ODQ76223.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1E3QEV0; -.
DR STRING; 675824.A0A1E3QEV0; -.
DR OrthoDB; 1532at2759; -.
DR Proteomes; UP000094385; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR GO; GO:0051179; P:localization; IEA:UniProt.
DR CDD; cd16991; ENTH_Ent1_Ent2; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR InterPro; IPR013809; ENTH.
DR InterPro; IPR008942; ENTH_VHS.
DR InterPro; IPR003903; UIM_dom.
DR PANTHER; PTHR12276; EPSIN/ENT-RELATED; 1.
DR PANTHER; PTHR12276:SF110; FI19443P1; 1.
DR Pfam; PF01417; ENTH; 1.
DR SMART; SM00273; ENTH; 1.
DR SMART; SM00726; UIM; 2.
DR SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR PROSITE; PS50942; ENTH; 1.
PE 3: Inferred from homology;
KW Lipid-binding {ECO:0000256|ARBA:ARBA00023121};
KW Reference proteome {ECO:0000313|Proteomes:UP000094385}.
FT DOMAIN 11..143
FT /note="ENTH"
FT /evidence="ECO:0000259|PROSITE:PS50942"
FT REGION 146..186
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 261..292
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 364..386
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 498..530
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 167..186
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 530 AA; 58989 MW; 8E9DD0FB3B1B3904 CRC64;
MSKSLMRSIK NVTNGYSSNQ IKVRNATSND PWGPVSTDMN EIAQCTFDPG SFMEIMDMIE
RRLNDKGKNW RHVMKALVVL DYCIHVGSED VVRWAKDNTY IIKTLREFQY IDEEGRDQGA
NVRAKAKDLT LLLLDDERIR TERVNRDNMR NKMGQPGDSM FNGESHASRP YEHRAPRRMP
VQSDFDNDED FRKALEESKL TAAEEDARRR ERHTFDNVVD EDMARAIKLS EQEAMKEQQR
AYFDTQNSNL LFDEYAPRET ASQQFAQSTG YPQSTSPFQV QSHSTGYQQS SSPFQTKYAN
CNNADLLLDV FAPSQSASQQ VHQATGQNPY SQQLFPQNTA QQVYPQKASP SAFSQNTSQL
LPFSSQSPFT TTATSQSPFS FSQATAPSTS RELSHSAFLF SQPTALQPVQ PVQSHLTEFS
ASSPPRPLQQ QSPANVFGQN SVFDPAAQHP VSTGFLQNAY SSSPFQGSGV TGNGGSTGQF
NAFGQSSYGP QSYLNSEFGG HAVHEDSAAK RSNNPFAKPA AANSNETSLL
//
