ID A0A1E3QEX7_LIPST Unreviewed; 909 AA.
AC A0A1E3QEX7;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ODQ76253.1};
GN ORFNames=LIPSTDRAFT_67134 {ECO:0000313|EMBL:ODQ76253.1};
OS Lipomyces starkeyi NRRL Y-11557.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Lipomycetaceae; Lipomyces.
OX NCBI_TaxID=675824 {ECO:0000313|EMBL:ODQ76253.1, ECO:0000313|Proteomes:UP000094385};
RN [1] {ECO:0000313|EMBL:ODQ76253.1, ECO:0000313|Proteomes:UP000094385}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL Y-11557 {ECO:0000313|EMBL:ODQ76253.1,
RC ECO:0000313|Proteomes:UP000094385};
RX PubMed=27535936; DOI=10.1073/pnas.1603941113;
RA Riley R., Haridas S., Wolfe K.H., Lopes M.R., Hittinger C.T., Goeker M.,
RA Salamov A.A., Wisecaver J.H., Long T.M., Calvey C.H., Aerts A.L.,
RA Barry K.W., Choi C., Clum A., Coughlan A.Y., Deshpande S., Douglass A.P.,
RA Hanson S.J., Klenk H.-P., LaButti K.M., Lapidus A., Lindquist E.A.,
RA Lipzen A.M., Meier-Kolthoff J.P., Ohm R.A., Otillar R.P., Pangilinan J.L.,
RA Peng Y., Rokas A., Rosa C.A., Scheuner C., Sibirny A.A., Slot J.C.,
RA Stielow J.B., Sun H., Kurtzman C.P., Blackwell M., Grigoriev I.V.,
RA Jeffries T.W.;
RT "Comparative genomics of biotechnologically important yeasts.";
RL Proc. Natl. Acad. Sci. U.S.A. 113:9882-9887(2016).
CC -!- SIMILARITY: Belongs to the peptidase M28 family. M28B subfamily.
CC {ECO:0000256|ARBA:ARBA00005634}.
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DR EMBL; KV454289; ODQ76253.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1E3QEX7; -.
DR STRING; 675824.A0A1E3QEX7; -.
DR OrthoDB; 67337at2759; -.
DR Proteomes; UP000094385; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd08022; M28_PSMA_like; 1.
DR CDD; cd02121; PA_GCPII_like; 1.
DR Gene3D; 3.50.30.30; -; 1.
DR Gene3D; 1.20.930.40; Transferrin receptor-like, dimerisation domain; 1.
DR Gene3D; 3.40.630.10; Zn peptidases; 1.
DR InterPro; IPR046450; PA_dom_sf.
DR InterPro; IPR003137; PA_domain.
DR InterPro; IPR007484; Peptidase_M28.
DR InterPro; IPR039373; Peptidase_M28B.
DR InterPro; IPR007365; TFR-like_dimer_dom.
DR InterPro; IPR036757; TFR-like_dimer_dom_sf.
DR PANTHER; PTHR10404:SF46; GLUTAMATE CARBOXYPEPTIDASE 2 HOMOLOG; 1.
DR PANTHER; PTHR10404; N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE; 1.
DR Pfam; PF02225; PA; 1.
DR Pfam; PF04389; Peptidase_M28; 1.
DR Pfam; PF04253; TFR_dimer; 1.
DR SUPFAM; SSF52025; PA domain; 1.
DR SUPFAM; SSF47672; Transferrin receptor-like dimerisation domain; 1.
DR SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000094385};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 141..162
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 296..365
FT /note="PA"
FT /evidence="ECO:0000259|Pfam:PF02225"
FT DOMAIN 483..673
FT /note="Peptidase M28"
FT /evidence="ECO:0000259|Pfam:PF04389"
FT DOMAIN 781..906
FT /note="Transferrin receptor-like dimerisation"
FT /evidence="ECO:0000259|Pfam:PF04253"
FT REGION 1..32
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 388..414
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 909 AA; 101625 MW; CA35F5D5EAA4B7D8 CRC64;
MPVPTDSHPL QSSDSPDEPH ENLELSDAPG SPIIADFHDA LGANNNEISG AESSAAIDLL
EYDEDGDENQ SLLHPQPRLA HGRHLFRNSI LTNSKHSTER ASSPTYTEDS LDSATEADLL
LPSPSSASSI REYFKKRWGT FFTRLLAYAL FGIVFIIGWK LVFLPRTTLR RDLARLRHFQ
VSLSDLERTL FGVPETSKVR EWSHYYTSGA HLAGTNYSQV QWTADKFKEY GFTAEIVSYE
TYLNYPRDHS LKLLDVHGTI RYEAPLKEDM LTQDPTTNDP NSVPTFHGYS ANGNVTAAYV
YVNYGRQEDY DLLEERGIDI SGKIVIARYG GLFRGLIVKG AQERGAVGAL LYTDPGDDGD
ITLVNKYRAY PDGPARNPSS VQRGSVLFLS SAPGDPTTPG FASKPGAERV DPHERIPSIP
SLPISYRDVL PLLIELNGMG LNPNDLGESW RGGLREYDYS TGPSTMDVNL YNAQDYKTTP
IWNAIGRIDG VIKDEVVILG NHRDAWIVGG AGDPNSGSAV LIELARAFGE LKSHGWKPLR
SIVLASWDGE EYGLLGSTEW GEDMARYLDA NALVYLNVDG AVTGSHFHAA ASPLLNTVLQ
EVMKRVPDPK GGYVYDHWLE ETEGRIGNLG SGSDYTVFQD HLGIPSIDFG FSEGSNAVYQ
YHSNYDSFHW MDKYGDPTWE YHVAMVKIWG LVALQLSEIE VISFDVVEYA RSLLSYFNDV
KTKISHIVSE DELSVDIYDG FYDCPEIPGS LIRECRYIDA SAIVDVDLPD LKLGWWYISS
SLRNCSDALD KLLSTATTFD AKSSYINKQY LTDYPWFKGY KKMRVYFQIQ GLNSQYRQFE
RKFLYEGGLD GREWFKHVVF APGVWTGYAG VTFPGLNEAL DARNISNTKR WLDIITERIS
QAVDLLSAN
//
