ID A0A1E3QN24_9ASCO Unreviewed; 2274 AA.
AC A0A1E3QN24;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=EF-hand domain-containing protein {ECO:0000259|PROSITE:PS50222};
GN ORFNames=BABINDRAFT_162700 {ECO:0000313|EMBL:ODQ78492.1};
OS Babjeviella inositovora NRRL Y-12698.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; CUG-Ser1 clade incertae sedis; Babjeviella.
OX NCBI_TaxID=984486 {ECO:0000313|EMBL:ODQ78492.1, ECO:0000313|Proteomes:UP000094336};
RN [1] {ECO:0000313|Proteomes:UP000094336}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL Y-12698 {ECO:0000313|Proteomes:UP000094336};
RG DOE Joint Genome Institute;
RA Riley R., Haridas S., Wolfe K.H., Lopes M.R., Hittinger C.T., Goker M.,
RA Salamov A., Wisecaver J., Long T.M., Aerts A.L., Barry K., Choi C.,
RA Clum A., Coughlan A.Y., Deshpande S., Douglass A.P., Hanson S.J.,
RA Klenk H.-P., Labutti K., Lapidus A., Lindquist E., Lipzen A.,
RA Meier-Kolthoff J.P., Ohm R.A., Otillar R.P., Pangilinan J., Peng Y.,
RA Rokas A., Rosa C.A., Scheuner C., Sibirny A.A., Slot J.C., Stielow J.B.,
RA Sun H., Kurtzman C.P., Blackwell M., Grigoriev I.V., Jeffries T.W.;
RT "Comparative genomics of biotechnologically important yeasts.";
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KV454435; ODQ78492.1; -; Genomic_DNA.
DR RefSeq; XP_018983820.1; XM_019129490.1.
DR STRING; 984486.A0A1E3QN24; -.
DR GeneID; 30147343; -.
DR OrthoDB; 1386981at2759; -.
DR Proteomes; UP000094336; Unassembled WGS sequence.
DR GO; GO:0034702; C:monoatomic ion channel complex; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0005216; F:monoatomic ion channel activity; IEA:InterPro.
DR GO; GO:0050896; P:response to stimulus; IEA:UniProt.
DR Gene3D; 1.10.287.70; -; 4.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR Gene3D; 1.20.120.350; Voltage-gated potassium channels. Chain C; 3.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR027359; Volt_channel_dom_sf.
DR PANTHER; PTHR45628; VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1; 1.
DR PANTHER; PTHR45628:SF7; VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1; 1.
DR Pfam; PF00520; Ion_trans; 4.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 4.
DR PROSITE; PS50222; EF_HAND_2; 1.
PE 4: Predicted;
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000094336};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448};
KW Voltage-gated channel {ECO:0000256|ARBA:ARBA00022882}.
FT TRANSMEM 586..605
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 649..668
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 759..777
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 783..813
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 886..909
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 921..940
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 946..963
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 975..1001
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1061..1087
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1325..1343
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1355..1375
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1395..1416
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1457..1474
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1567..1590
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1677..1698
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1710..1731
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1737..1756
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1776..1798
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1862..1887
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1906..1941
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT REGION 2154..2189
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2154..2168
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2274 AA; 258668 MW; D60E7791A2F67E36 CRC64;
MNFTNPSKKP KIWVTQDGVE LPEVDLNLSD EFVFSTPKTH MSQLSSNNDV TDYQSIHLSV
ASKSDTSLPA TRANLDASTG IRPHSQTSIH SDSLNSVHLT TQRNTSQMSN LSNLHSNSRA
SGLEDNMTAA LSGANAPTSW LPLRRGLTTS QTSPAPSIVN GKTLRAAPDF SEAYSMDFEE
YDSDPDAIKL HNITSASPRH RRAFRDSYDV EGLAPPSPTK VSLQTPKTKL AEAFQNFSAR
VSGRDDDVLL DHSDDGYFHD ATQSFDDIRP QVTADDASYL PASLRTDDFR SKTSVFAPSI
ITAPDNTSYA ASSIFPAPLR PMSAPNVPAS RLRLFGKSLG IFPPDSPLRL WCSVFLGRRY
VKHIPVMLLL LMTGMLSVQQ WSPLTHHSYY FDGYGWIDTV ILILNCLFMV EMGLKIVTFG
LWDDRQMFAE LHFLRTKSKL HKCVEKILSD MKVTDVVNKG KQMFGSRTGR RMKADKRGMF
PQPDNITYEP RGQSTYDPCP EASYGSSTKS PGYFYNQSEI KGYDSPNGNT EGGYPTNIED
YDVSDDLPLH NASILLPTST QLTSFALRNG DFRKLMLERA FLRSNWNILD LFSTLCYIVS
LFLSIDRYDV KHNIFLFRAL ACVRIFRLTA LTRGTHSILK AIRKAAPQLA NVALFVLCFW
IFFSILGVQS FKSSFDRMCT WTNPSDSTDT FVNTVNLQFC GSWLSGSGEI MEYIYEDGTV
SGRYKGFRCP INSKCISYSS SPNSWNYLSF DNIIDSMKMV AVIMTANTFS NIMYYTMDLD
LMPAALFFIA CIFFLTVWLL NVFAAVVVKS FILTLEEKQK RKKLLRIAMP DMARFMFADN
LARCGRPIAV RLYRVFERFC VLIISSGLVV QCLRSSGLDP ATLNTLIVYE SVVTLILLVE
IVLRFFAHFP LWRHFFRARQ NIVDLVLAVV TSIIIIPPLR VRMHHAYYWL TIFQIVRLYR
VAISLPYTRK LWTKVLGNIL TVFDLALFYL ILTFLYSIIV ARFFEGFVTA EENEAILEEN
LFSLSSLPNT ILAMFVITST ENWTQILYEM DQQSNNMSSR IFGDILLIGW FFASYVVIFN
IFVAIIAQNF DISEEDKRRY QLKKFVDESA QELEQLSRKN KVGNLDRLKT TLFKPKPNQV
NHGGFMQLLR NGQLMDTFLE KGNFRAIDED VYDHKKVRAG TSNNNHWMSE AQSSDGAAAV
DATEHAAASS ATRSSSFWAA FSPVHLRARL RGLRNYHHSP KPTSLDAEIS IDPRMLARKI
IQQQEAIAAE TQRMLRDKPN YNRVLGYFQP GHPLRRFCQS IMPLSFGERI RGVYPATLTR
DVVNVLFFCM TVSMVIIACY VTPLYRKEHN LDTGAWNWTV YTDFIFVVTF TLEFLVKVLA
DGLYFTPNGY FRSLWNSIDC VVLVTMWINV ISFLRYDDQL SRTIRGFKAL RALRLLTISK
RAQAYFHNTM IAGFRNIVGA AIVSLHLIVP YAVWGVNIFN GRLGLCVDGS SDRASCVNEY
TNNVGKWNVL SPNVYQEPRL NLNNFPRGLM SLYEILSLEG WLELLQSVTF TTGIGTVPSP
FASPFNAVFV VAYIFTGMIF ILTLFLSVII SKYAEVTGVA YYTTEQITWY DIAKFLKNVR
PSKRPDRNSM GRVRRVCYDL VLEHNVIWDR VVDCVLFIHL IMLMVEKYPS PYNYDFVRMV
LYTITTSVML QHYVMYAHAV GLRVFLRDKW NLFSSFVLIG ALCMSSLSFY VVDEGRATIY
GNFNKLFLMA ILLFAIPRSN RLSQLLKFAS SSLPSLGAVV FTWLVTFLVF AIAMNQIFGL
TKIGPNGTGN INFRTVTKSI IVLFRMSFGE GWNDIMDDFA VTSPDCYSGV GVNNTDCGNW
GYAYVLFTLW NIISMYIFVN MFISIVLDNF SYVYHSDSKT DLISRVEVRK FKRCWQRFDP
RGTGFIEPYD LHDMLHELGG VIKFKIYEGQ YTVPNLTQQW FTRKSSNPYD VELRPEAMQT
SLGRIDVAKV RFRRRVYERF LAEVYTVADE KHGGQINFTD LLLQLTLYTH FEEGECLNLP
DFLERNRTMT VVEEKLRTKK LAETMATVIC RWKYLQRKSA YDIRATNDNI SEIQKRLSAY
SEGLAWSSEG LADGMGDQNP AEFSHQRTLS RNDANVFDLP SMLISEYNES SVNQQTGAFG
QSGDNRPQSP KPRPRPLSLS PKPGSPVLIS GKNPFQSVMD GSPTYTGPMR APFDNPANET
NRHTLEHYME TDENPFVRDD ERVMNMLTDL GGAIEHSPWG AALKRVEDED EVKL
//
