ID A0A1E3QRU4_9ASCO Unreviewed; 685 AA.
AC A0A1E3QRU4;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=VPS10 domain-containing protein {ECO:0000259|SMART:SM00602};
DE Flags: Fragment;
GN ORFNames=BABINDRAFT_20654 {ECO:0000313|EMBL:ODQ80423.1};
OS Babjeviella inositovora NRRL Y-12698.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; CUG-Ser1 clade incertae sedis; Babjeviella.
OX NCBI_TaxID=984486 {ECO:0000313|EMBL:ODQ80423.1, ECO:0000313|Proteomes:UP000094336};
RN [1] {ECO:0000313|Proteomes:UP000094336}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL Y-12698 {ECO:0000313|Proteomes:UP000094336};
RG DOE Joint Genome Institute;
RA Riley R., Haridas S., Wolfe K.H., Lopes M.R., Hittinger C.T., Goker M.,
RA Salamov A., Wisecaver J., Long T.M., Aerts A.L., Barry K., Choi C.,
RA Clum A., Coughlan A.Y., Deshpande S., Douglass A.P., Hanson S.J.,
RA Klenk H.-P., Labutti K., Lapidus A., Lindquist E., Lipzen A.,
RA Meier-Kolthoff J.P., Ohm R.A., Otillar R.P., Pangilinan J., Peng Y.,
RA Rokas A., Rosa C.A., Scheuner C., Sibirny A.A., Slot J.C., Stielow J.B.,
RA Sun H., Kurtzman C.P., Blackwell M., Grigoriev I.V., Jeffries T.W.;
RT "Comparative genomics of biotechnologically important yeasts.";
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KV454430; ODQ80423.1; -; Genomic_DNA.
DR RefSeq; XP_018985751.1; XM_019131251.1.
DR AlphaFoldDB; A0A1E3QRU4; -.
DR STRING; 984486.A0A1E3QRU4; -.
DR GeneID; 30149104; -.
DR OrthoDB; 5840at2759; -.
DR Proteomes; UP000094336; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0007034; P:vacuolar transport; IEA:UniProt.
DR CDD; cd15482; Sialidase_non-viral; 1.
DR Gene3D; 2.10.70.80; -; 1.
DR Gene3D; 3.30.60.270; -; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR031777; Sortilin_C.
DR InterPro; IPR031778; Sortilin_N.
DR InterPro; IPR006581; VPS10.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR12106; SORTILIN RELATED; 1.
DR PANTHER; PTHR12106:SF27; VPS10 HOMOLOG 1-RELATED; 1.
DR Pfam; PF15902; Sortilin-Vps10; 1.
DR Pfam; PF15901; Sortilin_C; 1.
DR SMART; SM00602; VPS10; 1.
DR SUPFAM; SSF110296; Oligoxyloglucan reducing end-specific cellobiohydrolase; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000094336};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 656..678
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 2..643
FT /note="VPS10"
FT /evidence="ECO:0000259|SMART:SM00602"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ODQ80423.1"
FT NON_TER 685
FT /evidence="ECO:0000313|EMBL:ODQ80423.1"
SQ SEQUENCE 685 AA; 78065 MW; E86366077193FD95 CRC64;
DETILALTTQ NTCYVTHDQG YSWEIVAPGE EILSIHVNPY NSDHVYLIAA NQKVVYSRDR
ADNWKSFRTP SLPSPNTQPI RFHPRRDSWL IWLGQEGCTH PGSLSCRTVA YVSKSFGKRW
LEMQENVNMC SFIVKLHENT FNPLVLCDRP ATKSNNFRSE LMYSEDFFKT REVVLTNVVD
FETSGEYFFT TVEKGDSGVV EAYVSTNGKN WHKTSLPAGL ELSKHQAYTI ISATEYSVWM
HITTNDRSST EFGNILKSNS NGTYYNQIVS NVNRDLRGYV DFEKMEGIEG ISVINTVLNP
NEARAGARKK VKSQITHNDG GNWEYIHPPA IDSNGVKTPC YGNPLEKCSL NLHGYTERAD
YRDTFSSQGA LGMMVATGNV GETLQSLYDG NTYLTRDGGI TWKEVRKGVY MWEYGDQGSI
IVLVNSLDQT NEILYSLNEG DTWETFRFSE EKVWVEDIST VPSDNSKKFL LFTKLAMRHG
DRSRVFQIDF STLYKRKCNL DVQNLESTTD DFEIWSPQHP LSPDNCLFGR ETRYLRKIPG
RDCFIGTQVV QPHLIVKDCA CTRQDFECDF NYIRDKDDTC RLIAGYSPPN HLQDMCFDRK
GNRNKDQVEY WVSTGYRKIP LSTCKGGFEM DKKEVKACPG SNARFNEMYG ITKMGVFKAF
VSMLGVVGIS LVVGRYVVKN YGDKL
//
