ID   A0A1E3QU00_9ASCO        Unreviewed;       557 AA.
AC   A0A1E3QU00;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   RecName: Full=PNPLA domain-containing protein {ECO:0000259|PROSITE:PS51635};
DE   Flags: Fragment;
GN   ORFNames=BABINDRAFT_20442 {ECO:0000313|EMBL:ODQ81034.1};
OS   Babjeviella inositovora NRRL Y-12698.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; CUG-Ser1 clade incertae sedis; Babjeviella.
OX   NCBI_TaxID=984486 {ECO:0000313|EMBL:ODQ81034.1, ECO:0000313|Proteomes:UP000094336};
RN   [1] {ECO:0000313|Proteomes:UP000094336}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL Y-12698 {ECO:0000313|Proteomes:UP000094336};
RG   DOE Joint Genome Institute;
RA   Riley R., Haridas S., Wolfe K.H., Lopes M.R., Hittinger C.T., Goker M.,
RA   Salamov A., Wisecaver J., Long T.M., Aerts A.L., Barry K., Choi C.,
RA   Clum A., Coughlan A.Y., Deshpande S., Douglass A.P., Hanson S.J.,
RA   Klenk H.-P., Labutti K., Lapidus A., Lindquist E., Lipzen A.,
RA   Meier-Kolthoff J.P., Ohm R.A., Otillar R.P., Pangilinan J., Peng Y.,
RA   Rokas A., Rosa C.A., Scheuner C., Sibirny A.A., Slot J.C., Stielow J.B.,
RA   Sun H., Kurtzman C.P., Blackwell M., Grigoriev I.V., Jeffries T.W.;
RT   "Comparative genomics of biotechnologically important yeasts.";
RL   Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KV454428; ODQ81034.1; -; Genomic_DNA.
DR   RefSeq; XP_018986362.1; XM_019131246.1.
DR   AlphaFoldDB; A0A1E3QU00; -.
DR   STRING; 984486.A0A1E3QU00; -.
DR   GeneID; 30149099; -.
DR   OrthoDB; 154387at2759; -.
DR   Proteomes; UP000094336; Unassembled WGS sequence.
DR   GO; GO:0004806; F:triglyceride lipase activity; IEA:InterPro.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-UniRule.
DR   GO; GO:0006641; P:triglyceride metabolic process; IEA:UniProt.
DR   CDD; cd07230; Pat_TGL4-5_like; 1.
DR   Gene3D; 3.40.1090.10; Cytosolic phospholipase A2 catalytic domain; 2.
DR   InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR   InterPro; IPR002641; PNPLA_dom.
DR   InterPro; IPR021771; Triacylglycerol_lipase_N.
DR   PANTHER; PTHR14226; NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER; 1.
DR   PANTHER; PTHR14226:SF10; TRIACYLGLYCEROL LIPASE 4-RELATED; 1.
DR   Pfam; PF11815; DUF3336; 1.
DR   Pfam; PF01734; Patatin; 1.
DR   SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR   PROSITE; PS51635; PNPLA; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Lipid degradation {ECO:0000256|ARBA:ARBA00022963};
KW   Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW   Reference proteome {ECO:0000313|Proteomes:UP000094336}.
FT   DOMAIN          210..406
FT                   /note="PNPLA"
FT                   /evidence="ECO:0000259|PROSITE:PS51635"
FT   NON_TER         557
FT                   /evidence="ECO:0000313|EMBL:ODQ81034.1"
SQ   SEQUENCE   557 AA;  62049 MW;  57E1297FA188C0E0 CRC64;
     MSYPTLEFDP ADQYDSLTEI LFKRHSLLTE EEDGLFTNPF YRAAETAISF LRKVPLVGSF
     VPAASEADTQ VRALLAQQRA TTNYANWLDI STTLDRLLGN DAWKEAAESD YYDHGLVAAR
     LAQLRDARES GDYKRLLYLV RTTFVRNAGN IGNVNLYRHS YVGTKRLIEE YIDESERCLE
     LLTSGHTGLD PSYVLQMFIQ TRKNIGRTAL VLSGGGCFGL IHIGVLSTLM ESDLLPKIVS
     GLSAGSIVAS ILCSNTNDEI RTILSEIGEQ SINIFDDAGE TVWIKLSRFL KYGTWFDSGH
     LQLTMYEFLG DLTFRESYNR TGRILNITVS PASIHEQPRL LNYLTAPSVL IWSAVCASCS
     LPGVFASSTI YEKVPRTRVV QEWNGASSVK YVDGSVDNDV PITRLSEMFN VGHIIACQVN
     PHVAPLLKMS ISCVGGDVET EYSAWLKQSL SNLYGLMASE VIHYLDVAKE IGIARNLCTK
     ATSILSQKYS GDITILPELH LTELHKILQN PNPAFFLECT VRGARATWPK MTIIRNHCAL
     EFALDRGISQ LRSRLIS
//