ID A0A1E3QUA8_9ASCO Unreviewed; 644 AA.
AC A0A1E3QUA8;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE RecName: Full=PX domain-containing protein {ECO:0000259|PROSITE:PS50195};
GN ORFNames=BABINDRAFT_160644 {ECO:0000313|EMBL:ODQ81273.1};
OS Babjeviella inositovora NRRL Y-12698.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; CUG-Ser1 clade incertae sedis; Babjeviella.
OX NCBI_TaxID=984486 {ECO:0000313|EMBL:ODQ81273.1, ECO:0000313|Proteomes:UP000094336};
RN [1] {ECO:0000313|Proteomes:UP000094336}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL Y-12698 {ECO:0000313|Proteomes:UP000094336};
RG DOE Joint Genome Institute;
RA Riley R., Haridas S., Wolfe K.H., Lopes M.R., Hittinger C.T., Goker M.,
RA Salamov A., Wisecaver J., Long T.M., Aerts A.L., Barry K., Choi C.,
RA Clum A., Coughlan A.Y., Deshpande S., Douglass A.P., Hanson S.J.,
RA Klenk H.-P., Labutti K., Lapidus A., Lindquist E., Lipzen A.,
RA Meier-Kolthoff J.P., Ohm R.A., Otillar R.P., Pangilinan J., Peng Y.,
RA Rokas A., Rosa C.A., Scheuner C., Sibirny A.A., Slot J.C., Stielow J.B.,
RA Sun H., Kurtzman C.P., Blackwell M., Grigoriev I.V., Jeffries T.W.;
RT "Comparative genomics of biotechnologically important yeasts.";
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the sorting nexin family.
CC {ECO:0000256|ARBA:ARBA00010883}.
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DR EMBL; KV454428; ODQ81273.1; -; Genomic_DNA.
DR RefSeq; XP_018986601.1; XM_019128356.1.
DR AlphaFoldDB; A0A1E3QUA8; -.
DR STRING; 984486.A0A1E3QUA8; -.
DR GeneID; 30146209; -.
DR OrthoDB; 5475877at2759; -.
DR Proteomes; UP000094336; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:GOC.
DR GO; GO:0005768; C:endosome; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0042147; P:retrograde transport, endosome to Golgi; IEA:InterPro.
DR CDD; cd06867; PX_SNX41_42; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR044106; PX_Snx41/Atg20.
DR PANTHER; PTHR46979; SORTING NEXIN-41; 1.
DR PANTHER; PTHR46979:SF2; SORTING NEXIN-41; 1.
DR Pfam; PF00787; PX; 1.
DR SMART; SM00312; PX; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR PROSITE; PS50195; PX; 1.
PE 3: Inferred from homology;
KW Endosome {ECO:0000256|ARBA:ARBA00022753};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000094336}.
FT DOMAIN 149..274
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT REGION 1..82
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 537..559
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 43..62
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 541..559
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 644 AA; 72807 MW; BDD93398ADC8EF32 CRC64;
MEVLENPFVR STSPYDRPAT PEDSALPPVS HPPPDLYTSF FADEYDNNPQ SGYSIQEDTT
EGFMEESTGE PVGGSSEVGS DYSDEASMLV SHDQQSSHAV NAAGIKPQQT ELVENSMFIS
QNLDISDGLR SLIGQDSVPV QIAHTGRFSA YSQASNPHAP RQSLVSNVIY YTIDLNYGQF
VVQRRYSEFS SLRDALCRLY PTRYVPTIPE KHSFMNYILG GNNTLHSKIN LSIIEYRKRY
LTDFLVEIIG NPVYRPLKHC ELFIKFLDPS ESNWDAVIHS PPMTLIPTSY LLANPINPTE
AEGIRSLLPL PLVSQINAFK FQDTKAKDGE AYNVKFAQLE QRFHQSHRLV RELGTVSGKL
DNLYERLIKN YIELGGNLNN FALTVESSST TFRESVEAED EANHNLSLVI EKFGSTIDKN
FLHMEAFQYQ QQLQLHEHMK ISIGSKTQEL LKLLNFVKLK QIQLMLTQKK YQGYADSKKQ
IESRVEQNER LQDALLRGSE LSPSIAEAIQ RYETSHRRGA NGNGWFTVFG GKRASRPVDS
GVHGDNSSTH SLVSTNSSED QTEAHRKIKL LDDEMDSLKR LIQVIQADVN AVSEHVAVTL
DEECTLIAQD WLRIMMRNSR NIQIMSEENL SAWQELKDEI GELL
//
