ID   A0A1E3QZZ6_9ASCO        Unreviewed;       600 AA.
AC   A0A1E3QZZ6;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   24-JAN-2024, entry version 28.
DE   RecName: Full=VLRF1 domain-containing protein {ECO:0000259|Pfam:PF18826};
GN   ORFNames=BABINDRAFT_159641 {ECO:0000313|EMBL:ODQ83201.1};
OS   Babjeviella inositovora NRRL Y-12698.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; CUG-Ser1 clade incertae sedis; Babjeviella.
OX   NCBI_TaxID=984486 {ECO:0000313|EMBL:ODQ83201.1, ECO:0000313|Proteomes:UP000094336};
RN   [1] {ECO:0000313|Proteomes:UP000094336}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL Y-12698 {ECO:0000313|Proteomes:UP000094336};
RG   DOE Joint Genome Institute;
RA   Riley R., Haridas S., Wolfe K.H., Lopes M.R., Hittinger C.T., Goker M.,
RA   Salamov A., Wisecaver J., Long T.M., Aerts A.L., Barry K., Choi C.,
RA   Clum A., Coughlan A.Y., Deshpande S., Douglass A.P., Hanson S.J.,
RA   Klenk H.-P., Labutti K., Lapidus A., Lindquist E., Lipzen A.,
RA   Meier-Kolthoff J.P., Ohm R.A., Otillar R.P., Pangilinan J., Peng Y.,
RA   Rokas A., Rosa C.A., Scheuner C., Sibirny A.A., Slot J.C., Stielow J.B.,
RA   Sun H., Kurtzman C.P., Blackwell M., Grigoriev I.V., Jeffries T.W.;
RT   "Comparative genomics of biotechnologically important yeasts.";
RL   Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC   -!- SIMILARITY: Belongs to the ANKZF1/VMS1 family.
CC       {ECO:0000256|ARBA:ARBA00009262}.
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DR   EMBL; KV454426; ODQ83201.1; -; Genomic_DNA.
DR   RefSeq; XP_018988529.1; XM_019127792.1.
DR   AlphaFoldDB; A0A1E3QZZ6; -.
DR   STRING; 984486.A0A1E3QZZ6; -.
DR   GeneID; 30145645; -.
DR   OrthoDB; 8371at2759; -.
DR   Proteomes; UP000094336; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   InterPro; IPR047139; ANKZ1/VMS1.
DR   InterPro; IPR041175; VLRF1/Vms1.
DR   PANTHER; PTHR16036; ANKYRIN REPEAT AND ZINC FINGER DOMAIN-CONTAINING PROTEIN 1; 1.
DR   PANTHER; PTHR16036:SF2; ANKYRIN REPEAT AND ZINC FINGER DOMAIN-CONTAINING PROTEIN 1; 1.
DR   Pfam; PF18826; bVLRF1; 1.
DR   SUPFAM; SSF48403; Ankyrin repeat; 1.
PE   3: Inferred from homology;
KW   ANK repeat {ECO:0000256|ARBA:ARBA00023043};
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Endonuclease {ECO:0000256|ARBA:ARBA00022759};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW   Reference proteome {ECO:0000313|Proteomes:UP000094336};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          199..359
FT                   /note="VLRF1"
FT                   /evidence="ECO:0000259|Pfam:PF18826"
FT   REGION          249..272
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          539..572
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        250..272
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        539..559
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   600 AA;  67190 MW;  AD60A9DC13D25776 CRC64;
     MSLPQFKYKT EDLCVYNLPT EILQSMSLMY FDFSTTEVET PQLTEDALST SLAAMEVEAN
     ASLNTCTTCL VSFEGLDLTD KKEHYRTDLH RFNLKRKVNG LPPVQELEFA GLLETLEESI
     SGSEGSDDDR LDAIMETSAA EEPAGPISFT NTKSPFVFFK SPLVQEKCFG VYKVCFLPQQ
     MENPLESMLQ WKQQPGKSAL IMIGGGHFAG AIISHQRKST KGNTATAQMS LVDQLVDVIA
     HKTFHRYTVR KKQGGSQSAS DGSRGKASSA GSTIRRQMEV LLMTEVRELL QSWKSHLDQC
     DNIYVRSTGQ YNRSVLIGYE GAVLKVLDPR VRNFPFTTKR ATTSELRKAW VQLTTLALTD
     MPKSDAAAQE RAKRQEAILA QSRQSKQKEM KELTPEEVHT VEICLLVKKS RVPPLVAYFR
     KHGLSLDFVL EPGLENVLTP TVLHYASAAG QPHVVQALLT TLKADPTVAN VFGKTAWDVA
     AGDSRRAFQT ARHVLGEDYA DWSRAHVGAA KSREEFEQAA EAVQQEEKRL KAEAMAKARE
     VSEEEREREA REMKRKHMLG QGRSVGVLTQ VQNMSDLSEE QKMKLMREQR ARAAEARFKK
//