ID   A0A1E3R9I9_9MYCO        Unreviewed;       518 AA.
AC   A0A1E3R9I9;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   RecName: Full=Carboxylic ester hydrolase {ECO:0000256|RuleBase:RU361235};
DE            EC=3.1.1.- {ECO:0000256|RuleBase:RU361235};
GN   ORFNames=BHQ17_20270 {ECO:0000313|EMBL:ODQ86595.1};
OS   Mycolicibacterium holsaticum.
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC   Mycolicibacterium.
OX   NCBI_TaxID=152142 {ECO:0000313|EMBL:ODQ86595.1, ECO:0000313|Proteomes:UP000094243};
RN   [1] {ECO:0000313|Proteomes:UP000094243}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=M7 {ECO:0000313|Proteomes:UP000094243};
RA   Greninger A.L., Jerome K.R., Mcnair B., Wallis C., Fang F.;
RL   Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the type-B carboxylesterase/lipase family.
CC       {ECO:0000256|ARBA:ARBA00005964, ECO:0000256|RuleBase:RU361235}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ODQ86595.1}.
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DR   EMBL; MIGZ01000140; ODQ86595.1; -; Genomic_DNA.
DR   RefSeq; WP_069406907.1; NZ_MIGZ01000140.1.
DR   AlphaFoldDB; A0A1E3R9I9; -.
DR   ESTHER; 9myco-a0a1e3r9i9; Carb_B_Bacteria.
DR   OrthoDB; 3199405at2; -.
DR   Proteomes; UP000094243; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR002018; CarbesteraseB.
DR   InterPro; IPR019826; Carboxylesterase_B_AS.
DR   PANTHER; PTHR11559; CARBOXYLESTERASE; 1.
DR   PANTHER; PTHR11559:SF370; CARBOXYLIC ESTER HYDROLASE-RELATED; 1.
DR   Pfam; PF00135; COesterase; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR   PROSITE; PS00122; CARBOXYLESTERASE_B_1; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361235};
KW   Reference proteome {ECO:0000313|Proteomes:UP000094243}.
FT   DOMAIN          13..497
FT                   /note="Carboxylesterase type B"
FT                   /evidence="ECO:0000259|Pfam:PF00135"
SQ   SEQUENCE   518 AA;  55605 MW;  411FF41BB4E49CF6 CRC64;
     MTADAGRGTD HALVVDTAYG PVRGIDDGTV KFWKGVRYAA APVGELRWRA PEPPPRWTEP
     LDATRVGPVC PQPTDPKIPI DLGAPQGDDC LTLNVWASSD TAAGAAKPVM VWIHGGAYIL
     GSSAQPLYHG RALASAGEAI IVTVNYRLGA LGFLDLSSLD DQFATNIGIR DVLFALQWVR
     DNIAAFGGDP GRVTVFGESA GGGIVTTLLA SPPAAGLFGA AIAQSSPATS VYDRERGSRV
     AEQFLDALGM RTDEAHGLAS VPIAAVNAAA KRVFDAVPAS TPGTLAFAPI IDGDVVPAHP
     VKLAREGRTH PVPLLIGTNR HEAALFRWMK SPLMPITPQA IRDMFATIAA EQPALQLPSE
     AQIRATYRGR PKIIGMRVAR DIGFRMPSIW FAEGHRDVAP VYLYRFDFAT PMLRLLRLGA
     AHATELPYVW GNLVAGPKDP TFKLGGLKAG RVVSARMRTR WLNFAVDAAP AGRPGDPQWR
     PYRADERSTL VIDAEDRLVE DLDADVRTAW GDQVLSFR
//