ID A0A1E3SNS2_9MYCO Unreviewed; 433 AA.
AC A0A1E3SNS2;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=ATP-binding protein {ECO:0000313|EMBL:ODR03801.1};
GN ORFNames=AWC25_17060 {ECO:0000313|EMBL:ORW73988.1}, BHQ21_20050
GN {ECO:0000313|EMBL:ODR03801.1};
OS Mycobacterium sherrisii.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium simiae complex.
OX NCBI_TaxID=243061 {ECO:0000313|EMBL:ODR03801.1, ECO:0000313|Proteomes:UP000094224};
RN [1] {ECO:0000313|EMBL:ORW73988.1, ECO:0000313|Proteomes:UP000193024}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-832 {ECO:0000313|EMBL:ORW73988.1,
RC ECO:0000313|Proteomes:UP000193024};
RA Tarcisio F., Conor M., Antonella G., Elisabetta G., Giulia F.S., Sara T.,
RA Anna F., Clotilde B., Roberto B., Veronica D.S., Fabio R., Monica P.,
RA Olivier J., Enrico T., Nicola S.;
RT "The new phylogeny of the genus Mycobacterium.";
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000094224}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BC1_M4 {ECO:0000313|Proteomes:UP000094224};
RA Greninger A.L., Jerome K.R., Mcnair B., Wallis C., Fang F.;
RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:ODR03801.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BC1_M4 {ECO:0000313|EMBL:ODR03801.1};
RA Capua I., De Benedictis P., Joannis T., Lombin L.H., Cattoli G.;
RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the PINc/VapC protein family.
CC {ECO:0000256|ARBA:ARBA00038093}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ODR03801.1}.
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DR EMBL; MIHC01000040; ODR03801.1; -; Genomic_DNA.
DR EMBL; LQPT01000108; ORW73988.1; -; Genomic_DNA.
DR RefSeq; WP_069402041.1; NZ_MIHC01000040.1.
DR STRING; 243061.AWC25_17060; -.
DR OrthoDB; 9766527at2; -.
DR Proteomes; UP000094224; Unassembled WGS sequence.
DR Proteomes; UP000193024; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR CDD; cd09883; PIN_VapC_PhoHL-ATPase; 1.
DR Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003714; PhoH.
DR InterPro; IPR029060; PIN-like_dom_sf.
DR InterPro; IPR002716; PIN_dom.
DR PANTHER; PTHR30473:SF2; PIN DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR30473; PROTEIN PHOH; 1.
DR Pfam; PF02562; PhoH; 1.
DR Pfam; PF13638; PIN_4; 1.
DR SMART; SM00670; PINc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF88723; PIN domain-like; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000313|EMBL:ODR03801.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Nucleotide-binding {ECO:0000313|EMBL:ODR03801.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000094224};
KW Toxin-antitoxin system {ECO:0000256|ARBA:ARBA00022649}.
FT DOMAIN 5..132
FT /note="PIN"
FT /evidence="ECO:0000259|SMART:SM00670"
SQ SEQUENCE 433 AA; 46824 MW; B5A3C41C8D4F27D4 CRC64;
MTDIRTYVID TSVLLSDPWA CSRFAEHEVV VPLVVISELE AKRHHHELGW FARQALRLFD
DLRLEHGRLD QPIPVGTQGG SLHVELNHTD PAVLPAGFRT DSNDSRILSC AANLAAEGKR
VTLVSKDIPL RVKAAAVGLA ADEYHAQDVV ASGWSGMQEI ETAAEDIDAL FADGEIDLAE
ARDLPCHTGI RLLGGSSHAL GRVTAAKRVQ LVRGDREVFG LRGRSAEQRV ALDLLLDESV
GIVSLGGKAG TGKSALALCA GLEAVLERRT QRKVVVFRPL YAVGGQELGY LPGSESEKMG
PWAQAVFDTL EGLASPAVLE EVLSRGMLEV LPLTHIRGRS LHDSFVIVDE AQSLERNVLL
TVLSRLGTGS RVVLTHDIAQ RDNLRVGRHD GVAAVIEKLK GHPLFAHITL LRSERSPIAA
LVTEMLEEIA GPH
//
