ID A0A1E3SQZ8_9MYCO Unreviewed; 1204 AA.
AC A0A1E3SQZ8;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 24-JAN-2024, entry version 37.
DE SubName: Full=Murein biosynthesis protein MurJ {ECO:0000313|EMBL:ODR04560.1};
GN ORFNames=AWC25_02800 {ECO:0000313|EMBL:ORW82050.1}, BHQ21_17030
GN {ECO:0000313|EMBL:ODR04560.1};
OS Mycobacterium sherrisii.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium simiae complex.
OX NCBI_TaxID=243061 {ECO:0000313|EMBL:ODR04560.1, ECO:0000313|Proteomes:UP000094224};
RN [1] {ECO:0000313|EMBL:ORW82050.1, ECO:0000313|Proteomes:UP000193024}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-832 {ECO:0000313|EMBL:ORW82050.1,
RC ECO:0000313|Proteomes:UP000193024};
RA Tarcisio F., Conor M., Antonella G., Elisabetta G., Giulia F.S., Sara T.,
RA Anna F., Clotilde B., Roberto B., Veronica D.S., Fabio R., Monica P.,
RA Olivier J., Enrico T., Nicola S.;
RT "The new phylogeny of the genus Mycobacterium.";
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000094224}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BC1_M4 {ECO:0000313|Proteomes:UP000094224};
RA Greninger A.L., Jerome K.R., Mcnair B., Wallis C., Fang F.;
RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:ODR04560.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BC1_M4 {ECO:0000313|EMBL:ODR04560.1};
RA Capua I., De Benedictis P., Joannis T., Lombin L.H., Cattoli G.;
RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ODR04560.1}.
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DR EMBL; MIHC01000030; ODR04560.1; -; Genomic_DNA.
DR EMBL; LQPT01000045; ORW82050.1; -; Genomic_DNA.
DR RefSeq; WP_069401465.1; NZ_MIHC01000030.1.
DR STRING; 243061.AWC25_02800; -.
DR OrthoDB; 9786339at2; -.
DR Proteomes; UP000094224; Unassembled WGS sequence.
DR Proteomes; UP000193024; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0009252; P:peptidoglycan biosynthetic process; IEA:UniProtKB-KW.
DR GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
DR CDD; cd13123; MATE_MurJ_like; 1.
DR CDD; cd13973; PK_MviN-like; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR004268; MurJ.
DR PANTHER; PTHR47019; LIPID II FLIPPASE MURJ; 1.
DR PANTHER; PTHR47019:SF1; LIPID II FLIPPASE MURJ; 1.
DR Pfam; PF03023; MurJ; 1.
DR PRINTS; PR01806; VIRFACTRMVIN.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Cell shape {ECO:0000256|ARBA:ARBA00022960};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Peptidoglycan synthesis {ECO:0000256|ARBA:ARBA00022984};
KW Reference proteome {ECO:0000313|Proteomes:UP000094224};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 65..83
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 89..108
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 120..146
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 166..189
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 201..221
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 233..255
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 275..293
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 313..334
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 355..383
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 395..415
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 427..451
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 457..480
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 500..517
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 537..555
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 997..1019
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..30
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 576..716
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..28
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 585..612
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1204 AA; 125352 MW; A1C41A2703979D4C CRC64;
MNPAYRRPPA HQPPRRHQPP PTGPLPPVTE LPTRRVELSD SALVSRSWAM AFATLVSRIT
GFGRIVVLAA ILGAALSSAF SVANQLPNLV AALVLEATFT AIFVPVLARA EQSDPDGGAA
FVRRLVTVTT TLLLFATVVS VAAAPLLVRL MLGRDPQVNE PLTTAFAYLL LPQVLAYGLT
SVFMAILNTR NVFGPTAWAP VVNNVVALLT LAVYLVVPGQ LSVDPVRMGN AKLLVLGIGT
TLGVFAQTAV LLVALRRERV SLRPLWGIDE RLKRFGTMAA AMVLYVLISQ LGLVVGNQIA
STAAASGPAI YNYTWLVLML PFGMIGVTVL TVVMPRLSRN AAANDTGAVL ADLSLATRLT
LITLIPIVAF MTVGGPAIGS ALFAYGHFGG TDAGYLGAAI ALSAFTLIPY GLVLLQLRVF
YAREQPWTPI VIILVITAVK IAGSVLAPHV IDDPQLVAGF LGLANGIGFL AGAIVGYVLL
RHTLLPAGGH LVGRTEVRTV LVTTVASMLG GLIAHVVDRL LGLAELTAHG GAAGSLLRLL
ILGCLMLPIM ATVMVRAQVP EALAVVAAVR RRVGGGFRTA PPSRATATPR ASSHRRPVTY
PEQRNSSPPG VNAVQEPIRR RPPERAGNAR LMKGPEVTDR PVESAAPGPG AGGDRPRAAA
GDFQPEIPTA REPGPAFPQP PDQRNGGAVG DAGRGSMPAD ASRDRGAESP GDDAHLVPGA
RIAGGRYRLL VFHGGAPPLQ FWQALDTALD RQVALTFVDP DGSLPGDVLQ EILSRTLRLS
RIDKPGIARV LDVVHSQQGG LVVAEWIRGG SLQEVADTAP SPLGAVRAMQ SLAAAADAAH
RAGVALSIDH PSRIRVSIDG DVVLAYPATM PDANPEDDIR GIGASLYALL VNRWPLPESG
VRSGLAPAER DASGLPVEPS TIDRDIPFQV SAVAVRAAQE DGGIRSASTL LNLLQQATAV
ADRTEVLGPV DDSPPPPPAA PVERDEYATL ARRRRNLLIG GAAAIAVIVV ALLVLASIVS
KIFGNVGGGL NKDELGLNGP TSSSASSSAS AAPSGSVVKP IRATVYSPDG EADNPGQAGM
AIDGNSTTGW QTDIYTDAVP FPSFKNGVGL MLQLPSPTVV GAVSVDTPST GTKVEIRSSS
TPTPSRLEDT SLLVPATALK PGHNTIPVRA GAKTSNVLVW ITTLGNTDGK NRSELSNITI
QAAS
//
