ID A0A1E3T3J7_9MYCO Unreviewed; 1134 AA.
AC A0A1E3T3J7;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Nuclease {ECO:0000313|EMBL:ODR08990.1};
GN ORFNames=BHQ21_05225 {ECO:0000313|EMBL:ODR08990.1};
OS Mycobacterium sherrisii.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium simiae complex.
OX NCBI_TaxID=243061 {ECO:0000313|EMBL:ODR08990.1, ECO:0000313|Proteomes:UP000094224};
RN [1] {ECO:0000313|Proteomes:UP000094224}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BC1_M4 {ECO:0000313|Proteomes:UP000094224};
RA Greninger A.L., Jerome K.R., Mcnair B., Wallis C., Fang F.;
RL Submitted (SEP-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ODR08990.1}.
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DR EMBL; MIHC01000006; ODR08990.1; -; Genomic_DNA.
DR RefSeq; WP_069399242.1; NZ_MIHC01000006.1.
DR AlphaFoldDB; A0A1E3T3J7; -.
DR STRING; 243061.AWC25_10050; -.
DR Proteomes; UP000094224; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd17934; DEXXQc_Upf1-like; 1.
DR CDD; cd18808; SF1_C_Upf1; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR041679; DNA2/NAM7-like_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR019993; RecB_nuclease_TM0106_put.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR047187; SF1_C_Upf1.
DR InterPro; IPR038720; YprB_RNase_H-like_dom.
DR NCBIfam; TIGR03491; TM0106 family RecB-like putative nuclease; 1.
DR PANTHER; PTHR43788; DNA2/NAM7 HELICASE FAMILY MEMBER; 1.
DR PANTHER; PTHR43788:SF6; RECBCD ENZYME SUBUNIT RECD; 1.
DR Pfam; PF13087; AAA_12; 1.
DR Pfam; PF13604; AAA_30; 1.
DR Pfam; PF13482; RNase_H_2; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000094224}.
FT DOMAIN 312..499
FT /note="YprB ribonuclease H-like"
FT /evidence="ECO:0000259|Pfam:PF13482"
FT DOMAIN 916..1105
FT /note="DNA2/NAM7 helicase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13087"
SQ SEQUENCE 1134 AA; 123499 MW; 2EDAB8E82B6A4368 CRC64;
MFVTGDSVVY SASDLAAAAR CEYALLRDFD AKLGRGPAVT VEDELLARTA ALGDEHEHRE
LDRLRQEFPD GVAVIGRPAY TLAGLTAAAQ ATRRAIAERA PVVYQAAMFD GRFVGFADFL
VRDGDQYRLV DTKLARTPKV TALLQLAAYA DTLTGLGVSV ADEAELRLGD GSVMRYRVGD
LIPVFRSQRA LLQRLLDGHY AGGTAVSWDD MAVRACFRCP LCTEQVRASD DLLLVAGMRI
SQRNKIIDAG ISTVADLAEH RGPVPDLAAS ALEKLIAQAK IQVLQRDTAT AQFEVVDPRP
LALLPEPDPG DLFFDFEGDP LWTADGQDWG LEYLFGVLHA GGKFQPLWAH DRADERRALI
DFLALVAKRR KRHPNMHIYH YAPYEKTALL RLAGRYGVGE DQVDELLRCG VLVDLYPLVR
KSIRVGAESF SLKALEPLYM GAQLREGDVT TAADSITSYA RYCELRDAGR IDEAQTVLKD
IEDYNHYDCR STQELRNWLL VRAWESGVTP IGAQPVSDGN TVDDQDQLAA RLAAFAGDPA
VNPRTPAQVA VALVSAARGY HRREDKPFWW AHFDRLNFPV DEWADNTDVF VAETASVSVD
WHIPPRARKR QRRVTMRGEL ARGDLMTEVF ALYDPPAPAS MSDNPDRRAA GRATVVEVND
PAVPSEVVIA ERVGNDGNTF DQLPFALTPG PPIATTAMRE SIESTAAAVA AGLPQLPRTA
IIDVLLRRAP RTRGGGPLPR GSDAIADITE ATLALDSSYL AVHGPPGTGK TYTAAQVITR
LVTERNWRVG VVAQSHATVE NLLTAVIDAG LESGRVAKKK YDNRAARWQQ IDSSEYAAFI
STTVGCVIGG TAWDFANANR VTPGSLDLLV IDEAGQFCLA NTIAVAPAAA NLLLLGDPQQ
LPQVSQGTHP EPVDTSALEW LVDGQRTLPD ERGYFLDRSY RMHPAVCAAV SELAYEGRLH
SHDERTAARR LDGCRPGVRT LSVVHRSNSI ESPEEADAIV DQIRQLLGSC WTDEHGTRPL
AATDVLVLAP YNAQVSLIRR RLAAAGLDAV RVGTVDKFQG GQAAVVFISM TASSIEEVPR
GISFLLNRNR LNVAVSRAQY AAIIVRSELL TEYLPTTPAG LLELGAFLAL TASD
//
